Disposable cartridge concept for the on-demand synthesis of turbo Grignards, Knochel–Hauser amides, and magnesium alkoxides

Autor: Mateo Berton, Kevin Sheehan, Andrea Adamo, D. Tyler McQuade

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1343-1356 (2020)

Magnesium organometallic reagents occupy a central position in organic synthesis. The freshness of these compounds is the key for achieving a high conversion and reproducible results. Common methods for the synthesis of Grignard reagents from metalli

Externí odkaz: https://doaj.org/article/de958a6576fb4e3fa17a15a07e9daf61

A Continuous Flow Sulfuryl Chloride-Based Reaction—Synthesis of a Key Intermediate in a New Route toward Emtricitabine and Lamivudine

Autor: Mateo Berton, D. Tyler McQuade, David R. Snead, Juliana M. de Souza

Publikováno v: Organic Process Research & Development

We demonstrate a continuous two-step sequence in which sulfenyl chloride is formed, trapped by vinyl acetate, and chlorinated further via a Pummerer rearrangement. These reactions produce a key intermediate in our new approach to the oxathiolane core

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deefcc99ed6ad8881fc90e9c4f38b405
http://europepmc.org/articles/PMC7574626

Experimental Investigations on the Effects of Dissolved Gases on the Freezing Dynamics of Ocean Worlds

Autor: Christian Huber, Társilo Girona, James W. Head, Mateo Berton, Paul G. Williard, Hamid Karani, E. Nathan

Publikováno v: Journal of Geophysical Research: Planets. 125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91ddf1d7ca928d955ba8e8cfe6e32c16
https://doi.org/10.1029/2020je006528

A CONTINUOUS FLOW SULFURYL CHLORIDE BASED REACTION – SYNTHESIS OF A KEY INTERMEDIATE IN A NEW ROUTE TOWARD EMTRICITABINE AND LAMIVUDINE

Autor: D. Tyler McQuade, David Snead, Mateo Berton, Juliana de Souza

We demonstrate a continuous two-step sequence where a sulfenyl chloride is formed, trapped by vinyl acetate and chlorinated further via a Pummerer rearrangement. This sequence produces a key intermediate in our new approach to the oxathiolane core us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2c4d1af89301c1ec3ddd9bc2d8b50b5
https://doi.org/10.26434/chemrxiv.12056142

Photolysis of Tertiary Amines in the Presence of CO2: The Paths to Formic Acid, α-Amino Acids, and 1,2-Diamines

Autor: María Elena González Núñez, Rossella Mello, Rafael Acerete, Mateo Berton

Publikováno v: Berton, Mateo Otao Mello, Rossella C. C. Acerete, Rafael González Núñez, María Elena 2018 Photolysis of tertiary amines in the presence of CO2: the paths to formic acid, α-amino acids, and 1,2-diamines Journal of Organic Chemistry 83 1 96 103
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

The photolysis of triethylamine (1a) in the presence of carbon dioxide leads to the hydrogenation of CO2, the α-C-C coupling of triethylamine (1a), and the CO2-insertion into the α-C-H σ-bond of amine 1a. This reaction is proposed to proceed throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d147358675d0b123b5e0c720a2b983
https://doi.org/10.1021/acs.joc.7b02407