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pro vyhledávání: '"Mateja Salobir"'
Publikováno v:
International Journal of Pharmaceutics. 291:183-188
In this study we compared the effect of two surfactants (laureth-6 and sodium docusate) on the permeability of a model hydrophilic drug across three different epithelia (Caco-2 cells, stripped porcine jejunum and rat ileo-jejunum). Among the tested e
Publikováno v:
Biochemistry. 36:14345-14352
Thermal denaturation of equinatoxin II (EqTxII) in glycine buffer solutions (pH 1.1, 2.0, 3.0, and 3.5) and in triple distilled water (pH 5.5-6.0) was examined by differential scanning calorimetry, UV and CD spectroscopy and fluorescence emission spe
Publikováno v:
Biochemistry. 44(42)
Human erythropoietin (EPO) is a glycoprotein hormone considered to be the principal regulator of red blood cell formation. Although its recombinant version (rEPO) has been widely used for treatment of various anemias and its biological effects are re
Publikováno v:
International journal of pharmaceutics. 308(1-2)
The aim of the present study was to evaluate different pharmaceutically acceptable excipients as permeation enhancers for a low permeability drug, amoxicillin. As a model for the intestinal epithelium excised rat jejunum, mounted in side-by-side diff
Autor:
Đorđe Dmitrašinovič, Mateja Salobir, Miran Gaberšček, Odon Planinšek, Janko Jamnik, Marjan Bele, Stane Srčič
Publikováno v:
International journal of pharmaceutics. 291(1-2)
Pre-crystallized clarithromycin (6-O-methylerythromycin A) particles were coated with silica from the tetraethyl orthosilicate (TEOS)-ethanol-aqueous ammonia system. The coatings had a typical thickness of 100-150 nm and presented about 15 wt.% of th