Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Mateja Manček"'
Autor:
Tjaša Plaper, Jana Aupič, Petra Dekleva, Fabio Lapenta, Mateja Manček Keber, Roman Jerala, Mojca Benčina
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Coiled-coil (CC) dimer-forming peptides are attractive designable modules for mediating protein association. Highly stable CCs are desired for biological activity regulation and assay. Here, we report the design and versatile applications of
Externí odkaz:
https://doaj.org/article/24366d44f44440bd9d30fddabfebcaae
Autor:
Monika Avbelj, Iva Hafner-Bratkovič, Duško Lainšček, Mateja Manček-Keber, Tina Tinkara Peternelj, Gabriela Panter, Steven P. Treon, Boris Gole, Uroš Potočnik, Roman Jerala
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Coordination among multiple signaling pathways ensures an appropriate immune response, where a signaling pathway may impair or augment another signaling pathway. Here, we report a negative feedback regulation of signaling through the key innate immun
Externí odkaz:
https://doaj.org/article/07d262baefe74345bc4d7c340857165b
Autor:
Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno E. Correia, David Peterhoff, Ralf Wagner, Valter Bergant, Alexander Herrmann, Andreas Pichlmair, Roman Jerala
Publikováno v:
Vaccines, Vol 9, Iss 5, p 431 (2021)
The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptiv
Externí odkaz:
https://doaj.org/article/74784734a4764cf7add9be42d5336cc7
Autor:
Peter Pečan, Szabolcs Hambalkó, Van Thai Ha, Csilla T. Nagy, Csilla Pelyhe, Duško Lainšček, Bence Kenyeres, Gábor B. Brenner, Anikó Görbe, Ágnes Kittel, Monika Barteková, Péter Ferdinandy, Mateja Manček-Keber, Zoltán Giricz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7687 (2020)
Cardioprotection against ischemia/reperfusion injury is still an unmet clinical need. The transient activation of Toll-like receptors (TLRs) has been implicated in cardioprotection, which may be achieved by treatment with blood-derived extracellular
Externí odkaz:
https://doaj.org/article/b260a6f524c04976ab8f320b6f9f2062
Autor:
Mateja Manček-Keber, Rosana Ribić, Fernando Chain, Davy Sinnaeve, José C. Martins, Roman Jerala, Srđanka Tomić, Krisztina Fehér
Publikováno v:
Molecules, Vol 25, Iss 16, p 3707 (2020)
We report the enhancement of the lipopolysaccharide-induced immune response by adamantane containing peptidoglycan fragments in vitro. The immune stimulation was detected by Il-6 (interleukine 6) and RANTES (regulated on activation, normal T cell exp
Externí odkaz:
https://doaj.org/article/6882e42b1cd04aef851763dd6f3c27e5
Autor:
Zsófia Onódi, Csilla Pelyhe, Csilla Terézia Nagy, Gábor B. Brenner, Laura Almási, Ágnes Kittel, Mateja Manček-Keber, Péter Ferdinandy, Edit I. Buzás, Zoltán Giricz
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background: Extracellular vesicles (EVs) (isolated from blood plasma) are currently being extensively researched, both as biomarkers and for their therapeutic possibilities. One challenging aspect to this research is the efficient isolation of high-p
Externí odkaz:
https://doaj.org/article/1af025ed0b564df6a1f9569fd70a7f8d
Autor:
María Yáñez-Mó, Pia R.-M. Siljander, Zoraida Andreu, Apolonija Bedina Zavec, Francesc E. Borràs, Edit I. Buzas, Krisztina Buzas, Enriqueta Casal, Francesco Cappello, Joana Carvalho, Eva Colás, Anabela Cordeiro-da Silva, Stefano Fais, Juan M. Falcon-Perez, Irene M. Ghobrial, Bernd Giebel, Mario Gimona, Michael Graner, Ihsan Gursel, Mayda Gursel, Niels H. H. Heegaard, An Hendrix, Peter Kierulf, Katsutoshi Kokubun, Maja Kosanovic, Veronika Kralj-Iglic, Eva-Maria Krämer-Albers, Saara Laitinen, Cecilia Lässer, Thomas Lener, Erzsébet Ligeti, Aija Linē, Georg Lipps, Alicia Llorente, Jan Lötvall, Mateja Manček-Keber, Antonio Marcilla, Maria Mittelbrunn, Irina Nazarenko, Esther N.M. Nolte-‘t Hoen, Tuula A. Nyman, Lorraine O'Driscoll, Mireia Olivan, Carla Oliveira, Éva Pállinger, Hernando A. del Portillo, Jaume Reventós, Marina Rigau, Eva Rohde, Marei Sammar, Francisco Sánchez-Madrid, N. Santarém, Katharina Schallmoser, Marie Stampe Ostenfeld, Willem Stoorvogel, Roman Stukelj, Susanne G. Van der Grein, M. Helena Vasconcelos, Marca H. M. Wauben, Olivier De Wever
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-60 (2015)
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influen
Externí odkaz:
https://doaj.org/article/81410b260f724df3a5b0ed8e77723836
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92391 (2014)
Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartments but also at the plasma membrane. Overexpression of UNC93B1 promoted localization of TLR3, but not other nucleic acid sensing TLRs, to the plasma me
Externí odkaz:
https://doaj.org/article/efef2f1d87f74ca2aebc1ab5c68df4ea
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99287 (2014)
There is a well-established association between exposure to air pollutants and pulmonary injuries. For example, metals found in ROFA (residual oil fly ash) increase susceptibility of mice as well as humans to microbial infections. In our research, we
Externí odkaz:
https://doaj.org/article/e57c456ef134456f87aec83b9e0b0d1b
Autor:
Raquel Conde-Álvarez, Vilma Arce-Gorvel, Maite Iriarte, Mateja Manček-Keber, Elías Barquero-Calvo, Leyre Palacios-Chaves, Carlos Chacón-Díaz, Esteban Chaves-Olarte, Anna Martirosyan, Kristine von Bargen, María-Jesús Grilló, Roman Jerala, Klaus Brandenburg, Enrique Llobet, José A Bengoechea, Edgardo Moreno, Ignacio Moriyón, Jean-Pierre Gorvel
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002675 (2012)
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the gram-negative bacterium Brucel
Externí odkaz:
https://doaj.org/article/d8b9219f51be403aaa689ddaf9d2b218