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Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62250 (2013)
Employing DERA (2-deoxyribose-5-phosphate aldolase), we developed the first whole-cell biotransformation process for production of chiral lactol intermediates useful for synthesis of optically pure super-statins such as rosuvastatin and pitavastatin.
Externí odkaz:
https://doaj.org/article/62d7b09ebfa040f883a5332a49783f78
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62250 (2013)
PLoS ONE
PLoS ONE
Employing DERA (2-deoxyribose-5-phosphate aldolase), we developed the first whole-cell biotransformation process for production of chiral lactol intermediates useful for synthesis of optically pure super-statins such as rosuvastatin and pitavastatin.