Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics

Autor: Carmelo Bellardita, Navneet A. Vasistha, Susmita Malwade, Konstantin Khodosevich, Matej Andelic, Borna Moric, Irina Korshunova, Janina Gasthaus, Ole Kiehn

Publikováno v: Malwade, S, Gasthaus, J, Bellardita, C, Andelic, M, Moric, B, Korshunova, I, Kiehn, O, Vasistha, N A & Khodosevich, K 2022, ' Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics ', Biological Psychiatry, vol. 91, no. 8, pp. 727-739 . https://doi.org/10.1016/j.biopsych.2021.09.012

BACKGROUND: A number of rare copy number variants (CNVs) have been linked to neurodevelopmental disorders. However, because CNVs encompass many genes, it is often difficult to identify the mechanisms that lead to developmental perturbations.METHODS:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30ce498f8e211cbffd65fac9781faae
https://doi.org/10.1016/j.biopsych.2021.09.012