Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Matej, Vizovišek"'
Autor:
Livija Tušar, Jure Loboda, Francis Impens, Piotr Sosnowski, Emmy Van Quickelberghe, Robert Vidmar, Hans Demol, Koen Sedeyn, Xavier Saelens, Matej Vizovišek, Marko Mihelič, Marko Fonović, Jaka Horvat, Gregor Kosec, Boris Turk, Kris Gevaert, Dušan Turk
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Addressing the elusive specificity of cysteine cathepsins, which in contrast to caspases and trypsin-like proteases lack strict specificity determining P1 pocket, calls for innovative approaches. Proteomic analysis of cell lysates with human
Externí odkaz:
https://doaj.org/article/ca692483d89a43aea2681a5be3fe722b
Autor:
Federico Uliana, Matej Vizovišek, Laura Acquasaliente, Rodolfo Ciuffa, Andrea Fossati, Fabian Frommelt, Sandra Goetze, Bernd Wollscheid, Matthias Gstaiger, Vincenzo De Filippis, Ulrich auf dem Keller, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Characterizing proteases in their native environment is still challenging. Here, the authors develop a proteomics workflow for analyzing protease-specific peptides from cell lysates in 96-well format, providing mechanistic insights into blood proteas
Externí odkaz:
https://doaj.org/article/db933c0d43874f78b25c2f9000538975
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 1, Pp 50-57 (2019)
Legumain or asparagine endopeptidase is a unique cysteine endopeptidase with a distinctive specificity for the hydrolysis of peptide bonds after asparagine and to a lesser extent after aspartate. It is ubiquitously expressed in various tissues and be
Externí odkaz:
https://doaj.org/article/4b4c36c181f3416a9823130898149664
Autor:
Katarina Hočevar, Matej Vizovišek, Alicia Wong, Joanna Kozieł, Marko Fonović, Barbara Potempa, Richard J. Lamont, Jan Potempa, Boris Turk
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Porphyromonas gingivalis, the main etiologic agent of periodontitis, secretes cysteine proteases named gingipains. HRgpA and RgpB gingipains have Arg-specificity, while Kgp gingipain is Lys-specific. Together they can cleave an array of proteins and
Externí odkaz:
https://doaj.org/article/b5f84353b5654e30925e7e9b2cbb8b13
Autor:
Pál Tod, Beáta Róka, Tamás Kaucsár, Krisztina Szatmári, Matej Vizovišek, Robert Vidmar, Marko Fonovič, Gábor Szénási, Péter Hamar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5316 (2020)
(1) Background: Lipopolysaccharide (LPS)-induced systemic inflammation is associated with septic acute kidney injury (AKI). We investigated the time-dependent miRNA expression changes in the kidney caused by LPS. (2) Methods: Male outbred NMRI mice w
Externí odkaz:
https://doaj.org/article/a4791a13444045ba81edc2f09a9dbafb
Autor:
Beáta Róka, Pál Tod, Tamás Kaucsár, Matej Vizovišek, Robert Vidmar, Boris Turk, Marko Fonović, Gábor Szénási, Péter Hamar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 200 (2019)
(1) Background: Sepsis-induced acute kidney injury (AKI) is the most common form of acute kidney injury (AKI). We studied the temporal profile of the sepsis-induced renal proteome changes. (2) Methods: Male mice were injected intraperitoneally with b
Externí odkaz:
https://doaj.org/article/1bcc1f14f2714467826ee9fcc05f0b70
Publikováno v:
Cells, Vol 8, Iss 3, p 264 (2019)
For a long time, cysteine cathepsins were considered primarily as proteases crucial for nonspecific bulk proteolysis in the endolysosomal system. However, this view has dramatically changed, and cathepsins are now considered key players in many impor
Externí odkaz:
https://doaj.org/article/beefcf65dda94ff5b84f7abdc6077c6e
Autor:
Wioletta Rut, Marcin Poreba, Matej Vizovišek, Scott J. Snipas, Milind Pore, Guy S. Salvesen, Boris Turk, Katarzyna Groborz, Marcin Drag, Peter Kuhn
Publikováno v:
J Am Chem Soc
The subset of the proteome that contains enzymes in their catalytically active form can be interrogated by using probes targeted toward individual specific enzymes. A subset of such enzymes are proteases that are frequently studied with activity-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cff39ce0e5923250d8a38676155560
https://doi.org/10.1021/jacs.0c06762
https://doi.org/10.1021/jacs.0c06762
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 1, Pp 50-57 (2019)
Acta chimica slovenica
Acta chimica slovenica
Legumain or asparagine endopeptidase is a unique cysteine endopeptidase with a distinctive specificity for the hydrolysis of peptide bonds after asparagine and to a lesser extent after aspartate. It is ubiquitously expressed in various tissues and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f60e1311928bd38076ea34174ab4fdb
https://doi.org/10.17344/acsi.2018.4632
https://doi.org/10.17344/acsi.2018.4632
Autor:
Boris Turk, Marko Šoštar, Lucija Mijanović, Vedrana Filić, Matej Vizovišek, Marko Fonović, Jan Faix, Igor Weber, Alexander Junemann, Maja Marinović
Publikováno v:
Proceedings of the National Academy of Sciences
Macropinocytosis and phagocytosis are evolutionarily conserved forms of bulk endocytosis used by cells to ingest large volumes of fluid and solid particles, respectively. Both processes are regulated by Ras signaling, which is precisely controlled by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8539679044f3df8c16e6afd0d77c0466
https://doi.org/10.1073/pnas.1810268116
https://doi.org/10.1073/pnas.1810268116