Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Matej, Kastelic"'
Publikováno v:
Zdravniški Vestnik, Vol 83, Iss 9 (2014)
AbstractBackground. Approximately 30 % of patients with schizophrenia do not achieve remission upon antipsychotic treatment. The purpose of this article is to present the differences between treatment resistant and treatment responsive patients in Sl
Externí odkaz:
https://doaj.org/article/3cee000a2957427a8d0cd0fe9017a9a3
Publikováno v:
British Journal of Clinical Pharmacology. 82:399-411
Aims This study aimed to develop a population pharmacokinetic model for quantitative evaluation of the influence of genetic variants in metabolic enzymes and transporters on lamotrigine pharmacokinetics while taking into account the influence of vari
Publikováno v:
Journal of Molecular Neuroscience. 56:205-211
This study investigated the associations between single nucleotide polymorphisms in the neurodevelopmental Disrupted In Schizophrenia 1 (DISC1 ), neuregulin 1 (NRG1), brain-derived neurotrophic factor (BDNF) and NOTCH4 genes and the clinical symptoms
Publikováno v:
International Journal of Computer Assisted Radiology and Surgery, 12 (6)
International Journal of Computer Assisted Radiology and Surgery, 12 (6)
ISSN:1861-6410
ISSN:1861-6429
ISSN:1861-6410
ISSN:1861-6429
Publikováno v:
Psychiatria Danubina
Volume 28
Issue 2
Volume 28
Issue 2
Background: Dopaminergic system plays an important role in antipsychotic response. Functional single nucleotide polymorphisms (SNPs) can change dopamine receptor expression or dopamine disposition and thus influence response to antipsychotic treatmen
Autor:
Iztok Grabnar, Igor Locatelli, Aleš Mrhar, Blanka Kores-Plesnicar, Jure Koprivsek, Matej Kastelic, Vita Dolzan
Publikováno v:
European Journal of Pharmaceutical Sciences. 41:289-298
The objective of this prospective study was to characterize the metabolism of risperidone to (+)- and (-)-9-hydroxyrisperidone in vivo and to evaluate the influence of CYP2D6 genotype. A population pharmacokinetic modeling approach was used to estima
Autor:
Vita Dolžan, Alessandro Serretti, Laura Mandelli, Jure Koprivsek, Matej Kastelic, Iztok Grabnar, Igor Locatelli, Blanka Kores Plesničar
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 34:387-392
Polymorphic multidrug resistant protein 1 (MDR1) transports drugs against a concentration gradient across the blood–brain barrier and reduces their accumulation in the brain. MDR1 may therefore influence antipsychotic brain availability contributin
Publikováno v:
Neuropsychiatric Disease and Treatment
Tea TerziÄ,1 Matej Kastelic,2 Vita Dolžan,2 Blanka Kores PlesniÄar11Ljubljana University Psychiatric Hospital, Ljubljana, Slovenia; 2Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljublj
Autor:
Alessandro Serretti, Matej Kastelic, Blanka Kores Plesničar, Stefano Porcelli, Vita Dolžan, Anja Plemenitas
Heritability plays an important role in the development and expression of alcohol dependence. The present genetic association study explored the role of TPH2 polymorphisms and their haplotypes to investigate its role in alcohol dependence and comorbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b732385f4c2df8be3d2e41696200b36
http://hdl.handle.net/11585/542902
http://hdl.handle.net/11585/542902
Autor:
Stefan o Porcelli, Vita Dolžan, Anja Plemenitas, Alessandro Serretti, Blanka Kores Plesničar, Matej Kastelic
Publikováno v:
Neuropsychobiology. 72(1)
Background: Genes involved in the serotonin pathway may determine the susceptibility to alcohol dependence and its severity. The present study explored whether specific polymorphisms in the serotonin pathway could be associated with alcohol dependenc