Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Matei A, Banu"'
Autor:
Osama Al-Dalahmah, Michael G. Argenziano, Adithya Kannan, Aayushi Mahajan, Julia Furnari, Fahad Paryani, Deborah Boyett, Akshay Save, Nelson Humala, Fatima Khan, Juncheng Li, Hong Lu, Yu Sun, John F. Tuddenham, Alexander R. Goldberg, Athanassios Dovas, Matei A. Banu, Tejaswi Sudhakar, Erin Bush, Andrew B. Lassman, Guy M. McKhann, Brian J. A. Gill, Brett Youngerman, Michael B. Sisti, Jeffrey N. Bruce, Peter A. Sims, Vilas Menon, Peter Canoll
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain cells, including astrocytes, neurons and microglia/myeloid cells. This complex mixture of cell types forms the biological context for therapeutic r
Externí odkaz:
https://doaj.org/article/84706af8be0f4cffa61c89d018e75e54
Autor:
Michael G. Argenziano, Julia L. Furnari, Michael L. Miller, Yu Sun, Matei A. Banu, Justin A. Neira, Matija Snuderl, Jeffrey N. Bruce, Mary Welch, Paul McCormick, Peter Canoll
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-7 (2022)
Abstract We present the case of a 41-year-old man who developed worsening mid-thoracic back pain and imaging revealed a well-circumscribed intramedullary tumor in the thoracic spinal cord. Subtotal resection was performed, and histopathological analy
Externí odkaz:
https://doaj.org/article/0c25799048174155b51d0a19071a0280
Autor:
Alexander H. C. W. Agopyan-Miu, Matei A. Banu, Michael L. Miller, Christopher Troy, Gunnar Hargus, Peter Canoll, Tony J. C. Wang, Neil Feldstein, Aya Haggiagi, Guy M. McKhann
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-9 (2021)
Abstract Infratentorial oligodendrogliomas, a rare pathological entity, are generally considered metastatic lesions from supratentorial primary tumors. Here, we report the case of a 23-year-old man presenting with a histopathologically confirmed righ
Externí odkaz:
https://doaj.org/article/89faa0c82cd0471e860b8a9928295171
Autor:
Wenting Zhao, Athanassios Dovas, Eleonora Francesca Spinazzi, Hanna Mendes Levitin, Matei Alexandru Banu, Pavan Upadhyayula, Tejaswi Sudhakar, Tamara Marie, Marc L. Otten, Michael B. Sisti, Jeffrey N. Bruce, Peter Canoll, Peter A. Sims
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Preclinical studies require models that recapitulate the cellular diversity of human tumors and provide insight into the drug sensitivities of specific cellular populations. The ideal platform would enable rapid screening of cell
Externí odkaz:
https://doaj.org/article/9e1684ad81844398a6f6ff79f17cddee
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Current standard of care for glioblastoma is surgical resection followed by temozolomide chemotherapy and radiation. Recent studies have demonstrated that >95% extent of resection is associated with better outcomes, including prolonged progression-fr
Externí odkaz:
https://doaj.org/article/5f7c36a621a1470ca48172f639fc8bbe
Autor:
Brian J.A. Gill, Xiaoping Wu, Farhan A. Khan, Alexander A. Sosunov, Jyun-you Liou, Athanassios Dovas, Tahra L. Eissa, Matei A. Banu, Lisa M. Bateman, Guy M. McKhann, II, Peter Canoll, Catherine Schevon
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The purpose of this study is to develop a platform in which the cellular and molecular underpinnings of chronic focal neocortical lesional epilepsy can be explored and use it to characterize seizure-like events (SLEs) in an ex vivo model of infiltrat
Externí odkaz:
https://doaj.org/article/18f51f33fe1e4b86ac52923245678722
Autor:
Georg Karpel-Massler, Chiaki Tsuge Ishida, Elena Bianchetti, Yiru Zhang, Chang Shu, Takashi Tsujiuchi, Matei A. Banu, Franklin Garcia, Kevin A. Roth, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Glioblastoma (GBM) cells are often characterized by the presence of the IDH1 R132H mutation and high expression of anti-apoptotic proteins. Here, the authors show that the inhibition of Bcl-xL is synthetically lethal in IDH1-mutated GBM models and th
Externí odkaz:
https://doaj.org/article/0f3f4c1834e24518860d56a1a35c45d4
Autor:
Matei A. Banu, Athanassios Dovas, Michael G. Argenziano, Wenting Zhao, Henar Cuervo Grajal, Dominique M.O. Higgins, Colin P. Sperring, Brianna Pereira, Ling F. Ye, Aayushi Mahajan, Nelson Humala, Julia L. Furnari, Pavan S. Upadhyayula, Fereshteh Zandkarimi, Trang T. T. Nguyen, Peter B. Wu, Li Hai, Charles Karan, Aida Razavilar, Markus D. Siegelin, Jan Kitajewski, Jeffrey N. Bruce, Brent R. Stockwell, Peter A. Sims, Peter D. Canoll
Publikováno v:
bioRxiv
SUMMARYGlioma cells hijack developmental transcriptional programs to control cell state. During neural development, lineage trajectories rely on specialized metabolic pathways. However, the link between tumor cell state and metabolic programs is poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d307a66d6e7e7bb3360567afe6f972d
https://doi.org/10.1101/2023.02.22.529581
https://doi.org/10.1101/2023.02.22.529581
Autor:
Eleonora F Spinazzi, Michael G Argenziano, Pavan S Upadhyayula, Matei A Banu, Justin A Neira, Dominique M O Higgins, Peter B Wu, Brianna Pereira, Aayushi Mahajan, Nelson Humala, Osama Al-Dalahmah, Wenting Zhao, Akshay V Save, Brian J A Gill, Deborah M Boyett, Tamara Marie, Julia L Furnari, Tejaswi D Sudhakar, Sylwia A Stopka, Michael S Regan, Vanessa Catania, Laura Good, Stergios Zacharoulis, Meenu Behl, Petros Petridis, Sachin Jambawalikar, Akiva Mintz, Angela Lignelli, Nathalie Y R Agar, Peter A Sims, Mary R Welch, Andrew B Lassman, Fabio M Iwamoto, Randy S D’Amico, Jack Grinband, Peter Canoll, Jeffrey N Bruce
Publikováno v:
Lancet Oncol
Topotecan is cytotoxic to glioma cells but is clinically ineffective because of drug delivery limitations. Systemic delivery is limited by toxicity and insufficient brain penetrance, and, to date, convection-enhanced delivery (CED) has been restricte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af660e49bdf2f866c81191a11b49be0
https://pubmed.ncbi.nlm.nih.gov/36243021
https://pubmed.ncbi.nlm.nih.gov/36243021
Autor:
Binsheng Zhao, Peter Canoll, Jonathan Yun, Alexander Romanov, Xiaotao Guo, Timothy H. Ung, Jeffrey N. Bruce, Justin A. Neira, Matei A. Banu, Benjamin C. Kennedy, Nikita G. Alexiades, Randy S. D'Amico, Zachary K. Englander, Adam M. Sonabend, Robert J Rothrock
Publikováno v:
J Neurosurg
OBJECTIVEIntracerebral convection-enhanced delivery (CED) has been limited to short durations due to a reliance on externalized catheters. Preclinical studies investigating topotecan (TPT) CED for glioma have suggested that prolonged infusion improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a82b0b1b49ef376813912ddf282509c
https://doi.org/10.3171/2019.3.jns1963
https://doi.org/10.3171/2019.3.jns1963