Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Matam Vijay Kumar"'
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Although the liver is the largest metabolic organ in the body, it is not alone in functionality and is assisted by “an organ inside an organ,” the gut microbiota. This review attempts to shed light on the partnership between the liver an
Externí odkaz:
https://doaj.org/article/402ef80d81634393b157ab6d7b0a68f1
Autor:
Rachel M. Golonka, Beng San Yeoh, Piu Saha, Yuan Tian, John Y.L. Chiang, Andrew D. Patterson, Andrew T. Gewirtz, Bina Joe, Matam Vijay-Kumar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 719-735 (2024)
Background & Aims: Hepatocellular carcinoma (HCC) is a male-dominant disease, but targeted sex hormone therapies have not been successful. Bile acids are a potential liver carcinogen and are biomolecules with hormone-like effects. A few studies highl
Externí odkaz:
https://doaj.org/article/856932a29634485980da5951121e4bef
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/5998dfc581264db08bbe6b36e10976b6
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 3, Pp 333-335 (2024)
Studies in rodents suggest that inulin supplements may be carcinogenic. We present a case implicating that this risk extends to humans. A healthy male from a family lacking history of cancer had his first cancer-screening colonoscopy at age 56. No in
Externí odkaz:
https://doaj.org/article/864d89baffcc48bd99b5e9bdbd2d9397
Autor:
Alexis Bretin, Beng San Yeoh, Vu L. Ngo, Lavanya Reddivari, Michael Pellizzon, Matam Vijay-Kumar, Andrew T. Gewirtz
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTImpacts of dietary fiber on intestinal inflammation are complex, but some specific semi-purified fibers, particularly psyllium, can protect humans and rodents against colitis. Mechanisms underlying such protection are not fully understood but
Externí odkaz:
https://doaj.org/article/4dcf7474a67b4c528d91cee5fa06fed1
Autor:
Matam Vijay-Kumar, Venugopal R. Bovilla, Beng San Yeoh, Rachel M. Golonka, Piu Saha, Bina Joe, Andrew T. Gewirtz
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIntestinal contents comprise the largest repository of immunogenic ligands of microbial origin. We undertook this study to assess the predominant microbe-associated molecular patterns (MAMPs) present therein and the receptors) that mediate th
Externí odkaz:
https://doaj.org/article/c3c79b42d05b4519bab0a73d7871363a
Autor:
Alexis Bretin, Jun Zou, Beng San Yeoh, Vu L. Ngo, Shawn Winer, Daniel A. Winer, Lavanya Reddivari, Michael Pellizzon, William A. Walters, Andrew D. Patterson, Ruth Ley, Benoit Chassaing, Matam Vijay-Kumar, Andrew T. Gewirtz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1421-1442 (2023)
Background & Aims: Fiber-rich foods promote health, but mechanisms by which they do so remain poorly defined. Screening fiber types, in mice, revealed psyllium had unique ability to ameliorate 2 chronic inflammatory states, namely, metabolic syndrome
Externí odkaz:
https://doaj.org/article/b450f87359d34bd3a652ed5fa80e4482
Autor:
Sachin Aryal, Ishan Manandhar, Xue Mei, Beng S. Yeoh, Ramakumar Tummala, Piu Saha, Islam Osman, Jasenka Zubcevic, David J. Durgan, Matam Vijay-Kumar, Bina Joe
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 1 (2023)
The single largest contributor to human mortality is cardiovascular disease, the top risk factor for which is hypertension (HTN). The last two decades have placed much emphasis on the identification of genetic factors contributing to HTN. As a result
Externí odkaz:
https://doaj.org/article/92edb91623d54baa88eddd4ada3a4214
Autor:
Hao Q. Tran, Alexis Bretin, Aneseh Adeshirlarijaney, Beng San Yeoh, Matam Vijay-Kumar, Jun Zou, Timothy L. Denning, Benoit Chassaing, Andrew T. Gewirtz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 313-333 (2020)
Background & Aims: Consumption of a low-fiber, high-fat, Western-style diet (WSD) induces adiposity and adipose inflammation characterized by increases in the M1:M2 macrophage ratio and proinflammatory cytokine expression, both of which contribute to
Externí odkaz:
https://doaj.org/article/d5a47e3cffe746f6b56958102173e8d6
Autor:
Connor Campbell, Mrunmayee R. Kandalgaonkar, Rachel M. Golonka, Beng San Yeoh, Matam Vijay-Kumar, Piu Saha
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 294 (2023)
Gut microbes and their metabolites are actively involved in the development and regulation of host immunity, which can influence disease susceptibility. Herein, we review the most recent research advancements in the gut microbiota–immune axis. We d
Externí odkaz:
https://doaj.org/article/f3146a5e6efd4f8896295e2488801b7d