Molecular Genetics of Thrombotic Myeloproliferative Neoplasms: Implications in Precision Oncology

Autor: Yuh Cai Chia, Mat Jusoh Siti Asmaa, Marini Ramli, Peng Yeong Woon, Muhammad Farid Johan, Rosline Hassan, Md Asiful Islam

Publikováno v: Diagnostics, Vol 13, Iss 1, p 163 (2023)

Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include polycythaemia vera, essential thrombocythaemia, and primary myelofibrosis. Unlike monogenic disorders, a more complicated series of genetic mutations are believed to be responsible

Externí odkaz: https://doaj.org/article/186a64d3f6c04447a54742722fa9d4b5

Conformation sensitive gel electrophoresis for the detection of calreticulin mutations in BCR‐ABL1‐negative myeloproliferative neoplasms

Autor: Rosline Hassan, Muhammad Farid Johan, Shafini Mohamed Yusoff, Marini Ramli, Mat Jusoh Siti Asmaa, Mohd Yassim Haiyuni, Nur Atikah Zakaria, Sudin Aziee, Azlan Husin, Ibrahim Khidir Ibrahim, Norfifiana Alisa Rosle, Nurul Ameera Samat, Hamid Ali Nagi Al-Jamal

Publikováno v: International Journal of Laboratory Hematology. 43:1451-1457

Introduction Calreticulin (CALR) mutations in myeloproliferative neoplasms (MPN) have been reported to be key markers in the molecular diagnosis, particularly in patients lacking JAK2 V617F mutation. In most current reports, CALR mutations were analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f0ffbafb490674765483f315a8e39d
https://doi.org/10.1111/ijlh.13628

Apoptosis Induction in MV4-11 and K562 Human Leukemic Cells by Pereskia sacharosa (Cactaceae) Leaf Crude Extract

Autor: Cheng Yong Ang, Hamid Ali Nagi Al-Jamal, Azman Seeni, Muhammad Farid Johan, Mat Jusoh Siti Asmaa, Jamaruddin Mat Asan

Publikováno v: Asian Pacific Journal of Cancer Prevention. 15:475-481

Background: Pereskia sacharosa is a genus of cacti widely used in folk medicine for cancer-related treatment. Anti-proliferative effects have been studied in recent years against colon, breast, cervical and lung cancer cell lines, with promising resu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad84129eead52cb15bfc0ad9b56c006a
https://doi.org/10.7314/apjcp.2014.15.1.475

Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells

Autor: Al-Jamal HAN; Diagnostic and Biomedicine, Faculty of Health Science, Universiti Sultan Zainal Abidin, Gong Badak Compus, Kuala Nerus, Terengganu, Malaysia. Email: aljamalhamid@unisza.edu.my, Johan MF, Mat Jusoh SA, Ismail I, Wan Taib WR

Publikováno v: Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2018 Jun 25; Vol. 19 (6), pp. 1585-1590. Date of Electronic Publication: 2018 Jun 25.

Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia.

Autor: Al-Jamal HA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. aljamalhamid08@gmail.com., Mat Jusoh SA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. asma_sof88@yahoo.com., Hassan R; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. roslin@usm.my., Johan MF; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. faridjohan@usm.my.

Publikováno v: BMC cancer [BMC Cancer] 2015 Nov 07; Vol. 15, pp. 869. Date of Electronic Publication: 2015 Nov 07.