Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells

Autor: Al-Jamal HAN; Diagnostic and Biomedicine, Faculty of Health Science, Universiti Sultan Zainal Abidin, Gong Badak Compus, Kuala Nerus, Terengganu, Malaysia. Email: aljamalhamid@unisza.edu.my, Johan MF, Mat Jusoh SA, Ismail I, Wan Taib WR

Publikováno v: Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2018 Jun 25; Vol. 19 (6), pp. 1585-1590. Date of Electronic Publication: 2018 Jun 25.

Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia.

Autor: Al-Jamal HA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. aljamalhamid08@gmail.com., Mat Jusoh SA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. asma_sof88@yahoo.com., Hassan R; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. roslin@usm.my., Johan MF; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. faridjohan@usm.my.

Publikováno v: BMC cancer [BMC Cancer] 2015 Nov 07; Vol. 15, pp. 869. Date of Electronic Publication: 2015 Nov 07.