Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Matúš Miklovič"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The aim of the study was to clarify the role of the interplay between hypertension and the renin-angiotensin system (RAS) in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury. We hypothesized that in the late phase of hypertension w
Externí odkaz:
https://doaj.org/article/dbb7ae5a5b584842a647aa93460a5c97
Autor:
Dagmar Jarkovská, Matúš Miklovič, Jitka Švíglerová, Luděk Červenka, Petra Škaroupková, Vojtěch Melenovský, Milan Štengl
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic volume overload induces multiple cardiac remodeling processes that finally result in eccentric cardiac hypertrophy and heart failure. We have hypothesized that chronic angiotensin-converting enzyme (ACE) inhibition by trandolapril might affec
Externí odkaz:
https://doaj.org/article/4a0b94bb61c44b8cb14f97d32efb81e3
Autor:
Petr Kala, Matúš Miklovič, Šárka Jíchová, Petra Škaroupková, Zdeňka Vaňourková, Hana Maxová, Olga Gawrys, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, John D. Imig, John R. Falck, Josef Veselka, Luděk Červenka, Renáta Aiglová, Marek Vícha, Vít Gloger, Miloš Táborský
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1053 (2021)
This study evaluates the effects of chronic treatment with EET-A, an orally active epoxyeicosatrienoic acid (EETs) analog, on the course of aorto-caval fistula (ACF)-induced heart failure (HF) in Ren-2 transgenic rats (TGR), a model characterized by
Externí odkaz:
https://doaj.org/article/fc2f287a685341ddac7eacebb22f42da
Autor:
Petr Kala, Olga Gawrys, Matúš Miklovič, Zdenka Vaňourková, Petra Škaroupková, Šárka Jíchová, Janusz Sadowski, Elzbieta Kompanowska-Jezierska, Agnieszka Walkowska, Josef Veselka, Miloš Táborský, Hana Maxová, Ivana Vaněčková, Luděk Červenka
Publikováno v:
Journal of Hypertension. 41:99-114
Objective: Evaluation of the effect of endothelin type A (ETA) receptor blockade on the course of volume-overload heart failure in rats with angiotensin II-dependent hypertension. Methods: Ren-2 renin transgenic rats (TGR) were used as a model of hyp
Autor:
Tereza Tykvartova, Matus Miklovic, Martin Kotrc, Petra Skaroupkova, Ludmila Kazdova, Jaroslava Trnovska, Vojtech Skop, Michal Kolar, Jiri Novotny, Vojtech Melenovsky
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract While phosphodiesterase‐5 inhibition (PED5i) may prevent hypertrophy and failure in pressure‐overloaded heart in an experimental model, the impact of PDE5i on volume‐overload (VO)‐induced hypertrophy is unknown. It is also unclear wh
Externí odkaz:
https://doaj.org/article/d062805e3709438687a940351a7af7a8
Autor:
Tereza Havlenova, Petra Skaroupkova, Matus Miklovic, Matej Behounek, Martin Chmel, Dagmar Jarkovska, Jitka Sviglerova, Milan Stengl, Michal Kolar, Jiri Novotny, Jan Benes, Ludek Cervenka, Jiri Petrak, Vojtech Melenovsky
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Mechanisms of right ventricular (RV) dysfunction in heart failure (HF) are poorly understood. RV response to volume overload (VO), a common contributing factor to HF, is rarely studied. The goal was to identify interventricular differences i
Externí odkaz:
https://doaj.org/article/f251e8fd9382404c85c5d930444a3cba