Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Masuo Terashima"'
Autor:
Takatoshi Kakuta, Yoshinobu Sato, Tun Aung, Masuo Terashima, Miho Inagaki, Naoko Kagiwada, Akira Saito
Publikováno v:
Tissue Engineering. 11:1506-1515
To develop a bioartificial renal tubule system using renal tubular cells and porous polymer membrane hollow fibers, long-term maintenance of a confluent monolayer and the functionally differentiated condition of cells is essential. We examined the pr
Evaluation of long-term transport ability of a bioartificial renal tubule device using LLC-PK1 cells
Autor:
Takatoshi Kakuta, Masuo Terashima, Yoshinobu Sato, Nazira Ozgen, Akira Saito, Tun Aung, Chie Isoe
Publikováno v:
Nephrology Dialysis Transplantation. 19:2198-2207
Background. Haemodialysis therapy does not provide renal tubule function, such as active fluid and solute transport, nor metabolic or endocrine action. Moreover, this treatment is usually associated with serious complications and high mortality. We c
Autor:
Dennis Brown, Masuo Terashima, Johbu Itoh, Takayuki Tokimasa, Akira Saito, Yuji Fujita, Takatosi Kakuta
Publikováno v:
Tissue Engineering. 10:711-722
We investigated a portable bioartificial renal tubule device (BRTD) consisting of renal tubule cells and hollow fibers, to improve the quality of life of patients. It is necessary for a BRTD system to be compact. A compact portable BRTB requires tran
Autor:
Masuo Tokoo, Hiroshi Kasahara, Hironobu Saito, Masuo Terashima, Yukinori Kawahara, Hiroaki Shioys, Seiichi Furuta, Makoto Miyasaka, Kiyotaka Sato, Hisao Oguchi
Publikováno v:
Drug Investigation. 7:254-261
The single dose pharmacokinetics of temocapril, a novel prodrug type angiotensin converting enzyme (ACE) inhibitor with preferential biliary excretion, were evaluated in 6 patients maintained on haemodialysis and in 1 patient on continuous ambulatory
Publikováno v:
Drug Investigation. 7:191-199
The single dose pharmacokinetics of temocapril, a prodrug type angiotensin converting enzyme (ACE) inhibitor with a thiazepin ring, were studied in nephrectomised rats and compared with those of enalapril. The nephrectomised rats had much higher seru
Autor:
Tadaaki Maehara, Minoru Kimura, Natsuko Kikuchi, Masahiro Sato, Masuo Terashima, Shingo Nakamura, Akira Saito
Publikováno v:
BMC Nephrology, Vol 5, Iss 1, p 4 (2004)
BMC Nephrology
BMC Nephrology
Background Various animal models of renal failure have been produced and used to investigate mechanisms underlying renal disease and develop therapeutic drugs. Most methods available to produce such models appear to involve subtotal nephrectomy or in
Autor:
Y Sheng, Yuji Fujita, Takatoshi Kakuta, Katsuhiro Sugano, Masuo Terashima, Naoko Kagiwada, Manabu Asano, Shingo Nakamura, Akira Saito, Azusa Hasegawa
Publikováno v:
Artificial organs. 25(3)
Our aim was to develop bioartificial tubules using tubular epithelial cells and artificial membranes and evaluate the function of water and electrolyte transport by various tubular epithelial cells. The cells were cultivated onto extracellular matrix
Autor:
Seiichi Furuta, Shigeyuki Kawa, Mamoru Kobayashi, Hisao Oguchi, Masuo Terashima, Toshihiko Koiwai, Tatsuji Homma
Publikováno v:
Life sciences. 50(10)
We investigated the effects of ketanserin, a S 2 (5-hydroxytryptamine 2; 5-HT 2)-serotonergic receptor antagonist, on cerulein-induced pancreatitis in the rat. Large pharmacological doses of cerulein induced acute pancreatitis in the rat. Ketanserin
Autor:
Masuo Terashima, Hisao Oguchi, Yasutoshi Yanagisawa, Toshihiko Koiwai, Seiichi Furuta, Makoto Higuchi
Publikováno v:
Renal failure. 14(4)
To determine the effect of dibutyryl cyclic AMP (DBcAMP) on ischemic acute renal failure (IARF), that disorder was induced in male Wistar rats. After the animals were anesthetized with sodium pentobarbital (50 mg/kg, i.p.), the right kidney was remov
Publikováno v:
Hemodialysis International. 8:99-99
Introduction: A bioartificial kidney, which consists of a continuous hemofilter and a bioartificial tubule device using proximal tubular epithelial cells (LLC-PK1), is desired to develop for preventing long-term complications in hemodialysis patients