Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Masunobu Sugimura"'
Publikováno v:
European Journal of Pharmacology. 643:48-57
Bromocriptine, a dopamine D(2) receptor agonist, has widely been used for patients with Parkinson's disease. The aim of the present study was to investigate the effect of bromocriptine on glutamate transporter. Since the astroglial glutamate transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41f0cfefba2e6da21113d02655fdfa9
https://doi.org/10.1016/j.ejphar.2010.06.007
https://doi.org/10.1016/j.ejphar.2010.06.007
Autor:
Ken Osanai, Tetuya Mimura, Fusako Kito, Emi Ota, Shinichi Kawajiri, Masunobu Sugimura, Yoshiyuki Yoneda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2663-2666
We synthesized diaminobutane derivatives as potent Ca 2+ -permeable AMPA receptor antagonists with non-hypotensive activity. Compound 10c showed selective Ca 2+ -permeable AMPA receptor antagonist activity and neuroprotective effects in transient glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ed21fd945eafc5b6b08782f507d025
https://doi.org/10.1016/s0960-894x(01)00530-3
https://doi.org/10.1016/s0960-894x(01)00530-3
Publikováno v:
European Journal of Pharmacology. 370:117-123
Perturbations in Ca2+ homeostasis have been proposed to lead to neuronal damage after cerebral ischemia. DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1- (4-imidazolylethyl)-1H-indazole dihydrochloride 3.5 hydrate) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422d9d50c485974ec96acb26f709163a
https://doi.org/10.1016/s0014-2999(99)00133-8
https://doi.org/10.1016/s0014-2999(99)00133-8
Autor:
Shinichi Kawajiri, Yoshiyuki Yoneda, Ken Osanai, Tetuya Mimura, Fusako Kito, Emi Ota, Masunobu Sugimura
Publikováno v:
ChemInform. 33
We synthesized diaminobutane derivatives as potent Ca 2+ -permeable AMPA receptor antagonists with non-hypotensive activity. Compound 10c showed selective Ca 2+ -permeable AMPA receptor antagonist activity and neuroprotective effects in transient glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93fcb405280ba3fddfb95567e88b9f56
https://doi.org/10.1002/chin.200201246
https://doi.org/10.1002/chin.200201246
Autor:
Masunobu Sugimura, Masaki Saito, Takanori Yasukouchi, Shinichi Kawajiri, Masayuki Ito, Kei-ichi Kawagoe, Tetuya Mimura, Fusako Kito, Toshiaki Tatematu, Yoshiyuki Yoneda
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4e59aada0de31af02b171a3daaee6c
https://doi.org/10.1002/chin.200220046
https://doi.org/10.1002/chin.200220046
Publikováno v:
Journal of Pharmacobio-Dynamics. 15:75-78
Effects of a new thyrotropin-releasing hormone (TRH) analog, N alpha-[[(S)-4-oxo-2-azetidinyl]carbonyl]L-histidyl-L-prolinamide dihydrate (YM-14673), which improves experimentally induced memory dysfunction, on long-term potentiation (LTP) in the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2974a9d230c2c977da8e756a057016e1
https://doi.org/10.1248/bpb1978.15.75
https://doi.org/10.1248/bpb1978.15.75
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 207:119-128
The effects of several cerebroprotective and nootropic drugs on the function of excitatory amino acid (EAA) receptor subtypes expressed in Xenopus oocytes after injection of rodent brain poly(A)+ mRNA were investigated. The oocyte response to N- meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a35160b44d06f109135fb8fdfe787b
https://doi.org/10.1016/0922-4106(91)90086-w
https://doi.org/10.1016/0922-4106(91)90086-w
Publikováno v:
Neuropharmacology. 29:487-492
The susceptibilities to several drugs of long-term potentiations in the three input systems (mossy, commissural/associational and fimbrial fibres) to CA3 pyramidal neurones were investigated in hippocampal slices from the guinea pig. d -2-Amino-5-pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd0eab6e330e1becde2700383f55489
https://doi.org/10.1016/0028-3908(90)90171-m
https://doi.org/10.1016/0028-3908(90)90171-m
Autor:
Hiromichi Fukushi, Hideo Takamori, Yoshito Kanazawa, Yutaka Kitano, Masunobu Sugimura, Yasufumi Shirasaki
Publikováno v:
Biologicalpharmaceutical bulletin. 28(4)
DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate), a calmodulin antagonist, provides protection against Ca(2+) overload-associated cytotoxicity and brain inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028f73334b5a50f8fd1282b155e36cdd
https://pubmed.ncbi.nlm.nih.gov/15802800
https://pubmed.ncbi.nlm.nih.gov/15802800
Autor:
Hiromichi Takano, Yoshiyuki Morishima, Yoshito Kanazawa, Yasufumi Shirasaki, Masunobu Sugimura, Toshihiro Uchida
Publikováno v:
Biologicalpharmaceutical bulletin. 27(11)
An excessive elevation of intracellular Ca(2+) levels is known to play a key role in the pathological events following cerebral ischemia. DY-9760e, 3-[2-[4-(3-chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d35216e1844a7dfd0e75a18c88bfcb
https://pubmed.ncbi.nlm.nih.gov/15516724
https://pubmed.ncbi.nlm.nih.gov/15516724