Development of a Commercial Manufacturing Process for Vepdegestrant, an Orally Bioavailable PROTAC Estrogen Receptor Degrader for the Treatment of Breast Cancer.

Autor: Avery, Steve, Buske, Jamie M., Chen, Doris, Chen, Herman, Chen, Xin, Davidson, Andrew R., Desrosiers, Jean-Nicolas, Dong, Hanqing, Fellah, Noalle, Fernández, David F., Grosso, John, Han, Lu, Hochdorfer, Teri, Johnson, Amber M., Jones, Brian P., Kalinowski, Maciej, Launer-Felty, Katherine D., Lopez, Jorge, Makowski, Teresa, Mastriano, Carolyn

Publikováno v: Organic Process Research & Development; 11/15/2024, Vol. 28 Issue 11, p4079-4090, 12p

Bis(catecholato-κ ² O , O ')bis-(dimethyl sulfoxide-κ O )titanium(IV).

Autor: Hewage N; Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA., Mastriano C; Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA., Brückner C; Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA., Zeller M; Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN, 47907-2084, USA.

Publikováno v: Acta crystallographica. Section E, Crystallographic communications [Acta Crystallogr E Crystallogr Commun] 2022 Mar 15; Vol. 78 (Pt 4), pp. 385-391. Date of Electronic Publication: 2022 Mar 15 (Print Publication: 2022).