Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Masthan Thamim"'
Publikováno v:
Molecules, Vol 28, Iss 5, p 2315 (2023)
Mutations in homodimeric isocitrate dehydrogenase (IDH) enzymes at specific arginine residues result in the abnormal activity to overproduce D-2 hydroxyglutarate (D-2HG), which is often projected as solid oncometabolite in cancers and other disorders
Externí odkaz:
https://doaj.org/article/b2b08b9aef0641f89834faab6cbc5651
Autor:
G. Muni Hemalatha, Kandasamy Thirunavukkarasu, C. Ramesh Kumar, Masthan Thamim, Krishnan Thirumoorthy
Publikováno v:
ChemistrySelect. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda2f713f34332bcb59da7447a6a4ddf
https://doi.org/10.1002/slct.202204898
https://doi.org/10.1002/slct.202204898
Publikováno v:
European Biophysics Journal. 49:549-559
Chiral discrimination in biological systems, such as L-amino acids in proteins and d-sugars in nucleic acids, has been proposed to depend on various mechanisms, and chiral discrimination by mutated enzymes mediating cancer cell signaling is important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7160a91cf5ddf1318faf6bbe8a5137
https://doi.org/10.1007/s00249-020-01460-x
https://doi.org/10.1007/s00249-020-01460-x
Publikováno v:
Applied Organometallic Chemistry. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c6c0e3aab5f751f72cc4cc0abfc2ab3
https://doi.org/10.1002/aoc.5537
https://doi.org/10.1002/aoc.5537
Computational studies of selective N-methylation in nicotinamide: Epigenetic reprogramming in cancer
Autor:
Masthan Thamim, Krishnan Thirumoorthy
Publikováno v:
Computational and Theoretical Chemistry. 1194:113058
Methylation is one of the fundamental mechanisms of biotransformation reactions followed in nature that can modify the structure and functions of biomolecules. The nicotinamide N-methyltransferase (NNMT) is a human methyltransferase that produces 1-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc139966932f14701af0df84b015f93
https://doi.org/10.1016/j.comptc.2020.113058
https://doi.org/10.1016/j.comptc.2020.113058