Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Massimo Saini"'
Autor:
Ofer Regev, Marina Kizner, Francesco Roncato, Maya Dadiani, Massimo Saini, Francesc Castro-Giner, Olga Yajuk, Stav Kozlovski, Nehora Levi, Yoseph Addadi, Ofra Golani, Shifra Ben-Dor, Zvi Granot, Nicola Aceto, Ronen Alon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Breast tumors and their derived circulating cancer cells express the leukocyte β2 integrin ligand Intercellular adhesion molecule 1 (ICAM-1). We found that elevated ICAM-1 expression in breast cancer cells results in a favorable outcome and prolonge
Externí odkaz:
https://doaj.org/article/d9e88f61fbda4bd2a272841d63826b3e
Autor:
Anna Lorentzen, Paul F. Becker, Jan Kosla, Massimo Saini, Kathrin Weidele, Paolo Ronchi, Corinna Klein, Monika J. Wolf, Felix Geist, Bastian Seubert, Marc Ringelhan, Daniela Mihic-Probst, Knud Esser, Marko Roblek, Felix Kuehne, Gaia Bianco, Tracy O’Connor, Quentin Müller, Kathleen Schuck, Sebastian Lange, Daniel Hartmann, Saskia Spaich, Olaf Groß, Jochen Utikal, Sebastian Haferkamp, Martin R. Sprick, Amruta Damle-Vartak, Alexander Hapfelmeier, Norbert Hüser, Ulrike Protzer, Andreas Trumpp, Dieter Saur, Nachiket Vartak, Christoph A. Klein, Bernhard Polzer, Lubor Borsig, Mathias Heikenwalder
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
Polarisation of metastasising cancer cells in circulation has not been investigated before. Here the authors identify single cell polarity as a distinct polarisation state of single cells in liquid phase, and show that perturbing single cell polarity
Externí odkaz:
https://doaj.org/article/e4d4ca03df544a909e2ed53aef5fd83a
Publikováno v:
Cancer Research
The crosstalk between cancer cells and the immune system is crucial for disease progression and its therapeutic targeting is providing exciting results, in particular with newly developed immune checkpoint inhibitors. Current approaches primarily foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68253bfe60c4018f584e1653f38c5496
https://doi.org/10.1158/0008-5472.can-19-1972
https://doi.org/10.1158/0008-5472.can-19-1972
Autor:
Zoi Diamantopoulou, Francesc Castro-Giner, Fabienne Dominique Schwab, Christiane Foerster, Massimo Saini, Selina Budinjas, Karin Strittmatter, Ilona Krol, Bettina Seifert, Viola Heinzelmann-Schwarz, Christian Kurzeder, Christoph Rochlitz, Marcus Vetter, Walter Paul Weber, Nicola Aceto
Publikováno v:
Nature
Nature, 607 (7917)
Nature, 607 (7917)
The metastatic spread of cancer is achieved by the haematogenous dissemination of circulating tumour cells (CTCs). Generally, however, the temporal dynamics that dictate the generation of metastasis-competent CTCs are largely uncharacterized, and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b158ee86c223a9f30e3625cc1e41cdc
https://pubmed.ncbi.nlm.nih.gov/35963232
https://pubmed.ncbi.nlm.nih.gov/35963232
Autor:
Marica Eoli, Francesca Farina, Bernhard Gentner, Alessia Capotondo, Elena Anghileri, Matteo Barcella, Valentina Brambilla, Maria Grazia Bruzzone, Matteo Carrabba, Valeria Cuccarini, Giorgio d’Alessandris, Francesco Di Meco, Valeria Ferla, Alberto Franzin, Paolo Ferroli, Filippo Gagliardi, Federico Legnani, Stefania Mazzoleni, Pietro Mortini, Matteo Maria Naldini, Alessandro Olivi, Roberto Pallini, Monica Patanè, Rosina Paterra, Bianca Pollo, Massimo Saini, Silvia Snider, Luigi Naldini, Carlo Russo, Gaetano Finocchiaro, Fabio Ciceri
Publikováno v:
Neuro-Oncology Advances. 4:i7-i7
We developed an autologous hematopoietic stem cell-based platform designed to deliver IFNa, by a transcriptional and post-transcriptional control mechanism mediated by miRNA target sequences, specifically into the tumor microenvironment (TME) via Tie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff5c0648ba135a9ee13700d8b7482c24
https://doi.org/10.1093/noajnl/vdac078.028
https://doi.org/10.1093/noajnl/vdac078.028
Autor:
Sarah-Jane Neuberth, Corinna Schumacher, Marteinn Thor Snaebjörnsson, Roberto Würth, Franziska Maria Zickgraf, Ornella Kossi, Felix Geist, Andrea Geist, Vera Thiel, Jonas Schwickert, Mattia Falcone, Massimo Saini, Almut Schulze, Andreas Trumpp, Martin R. Sprick
Publikováno v:
Cancer Research. 82:652-652
Despite advances in the treatment of breast cancer, it is still the second leading cause of cancer-related death in women worldwide. A large number of patients develop recurrence and die of advanced metastatic disease. More than 70% of metastatic bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f07663d76da45e5d31fb3419085a64
https://doi.org/10.1158/1538-7445.am2022-652
https://doi.org/10.1158/1538-7445.am2022-652
Autor:
Massimo Saini, Laura Eichelberger, Gunnar Schotta, Simon Haas, Christina Scheel, Helena Dominguez Moreno, Melanie Koenigshoff, Manuel Reitberger, T. M. Strom, Marc Suetterlin, Corinna Klein, Vanessa Vogel, Martin R. Sprick, Saskia Spaich, Nicole Pfarr, Andreas Trumpp, Thomas Schwarzmayr, Elisabeth Graf, Elisa Espinet, Johanna M Bartsch, Andreas Schneeweiss, Wilko Weichert, Mattia Falcone, Mareike Lehmann, Elisa Donato, Roberto Wuerth
Despite important advances in the treatment of breast cancer, the 5-year survival rate for patients with distant metastasis remains less than 30%. Metastasis is a complex, multi-step process beginning with local invasion and ending with the outgrowth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87c5f506901cbaf1811f0c55058dc0b
Autor:
Sara Y. Brucker, Martin R. Sprick, Massimo Saini, Frederik Marmé, Markus Wallwiener, Florian Schütz, Dirk Jäger, Andreas Trumpp, Andreas Schneeweiss, Sabine Riethdorf, Sarah F. Jauch, TM Deutsch, Peter Sinn, Klaus Pantel, Juliane Nees, Birgitt Schönfisch, Christof Sohn, Barbara Burwinkel, Lisa Becker
Publikováno v:
Breast Cancer Research and Treatment. 173:155-165
Serial longitudinal enumeration of circulating tumor cells (CTCs) has shown its prognostic value on progression-free survival and overall survival (OS) in patients with stage IV breast cancer. This study prospectively evaluated the role of CTCs as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdc18e30ba92e996eb9d06d0643bfd7
https://doi.org/10.1007/s10549-018-4972-y
https://doi.org/10.1007/s10549-018-4972-y
Autor:
Richard M. White, Emily Montal, Maxime Deforet, Julia Newton-Bishop, Magdalena Katarzyna Sznurkowska, Mitchell P. Levesque, Mohita Tagore, Robert A. Cornell, Massimo Saini, Jérémie Nsengimana, Joao B. Xavier, Silja Heilmann, Sarah C. Perlee, Maomao Zhang, David J. Adams, Miranda V. Hunter, Manik Garg, Anjali Rao, Nicola Aceto, Nathaniel R. Campbell, Itai Yanai, Pippa Corrie, Roy Rabbie, Lorenza P. Ferretti, Colin Kenny, Luzia Briker, Mark R. Middleton, Ting-Hsiang Huang, Maayan Baron
Publikováno v:
Dev Cell
Melanomas can have multiple co-existing cell states, including proliferative (PRO) versus invasive (INV) subpopulations that represent a “go or grow” tradeoff; however, how these populations interact is poorly understood. Using a combination of z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93cbdfe908544286b9d78e9cf87d310
https://doi.org/10.1016/j.devcel.2021.08.018
https://doi.org/10.1016/j.devcel.2021.08.018
Autor:
Massimo Saini, Nicola Aceto
Publikováno v:
Clinical Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e53c6d8de312ed040a49c810b04c96