Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Massimo Pietropaolo"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 33, Iss , Pp 101413- (2023)
Autoantibodies targeting epitopes contained within the intracellular domain (IC) of the protein phosphatase-like islet antigen 2 (IA-2) are a common marker of autoimmune type 1 diabetes (T1D), however the isolation of genuine, serum derived anti-IA-2
Externí odkaz:
https://doaj.org/article/2742f9c0031248df92e55b4fe91b0510
Autor:
Rita C. Andersen, Jan H. Schmidt, Joscha Rombach, Matthew D. Lycas, Nikolaj R. Christensen, Viktor K. Lund, Donnie S. Stapleton, Signe S. Pedersen, Mathias A. Olsen, Mikkel Stoklund, Gith Noes-Holt, Tommas T.E. Nielsen, Mark P. Keller, Anna M. Jansen, Rasmus Herlo, Massimo Pietropaolo, Jens B. Simonsen, Ole Kjærulff, Birgitte Holst, Alan D. Attie, Ulrik Gether, Kenneth L. Madsen
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Bin/amphiphysin/Rvs (BAR) domains are positively charged crescent-shaped modules that mediate curvature of negatively charged lipid membranes during remodeling processes. The BAR domain proteins PICK1, ICA69, and the arfaptins have recently been demo
Externí odkaz:
https://doaj.org/article/283f087eadbe4c509ab194ae13855604
Autor:
Angela Subauste, Roberto Gianani, Annette M Chang, Cynthia Plunkett, Susan L Pietropaolo, Ying-Jian Zhang, Emma Barinas-Mitchell, Lewis H Kuller, Andrzej Galecki, Jeffrey B Halter, Massimo Pietropaolo
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106537 (2014)
There is a paucity of literature describing metabolic and histological data in adult-onset autoimmune diabetes. This subgroup of diabetes mellitus affects at least 5% of clinically diagnosed type 2 diabetic patients (T2DM) and it is termed Latent Aut
Externí odkaz:
https://doaj.org/article/acf064debaab47c4acfb1cf4f1bdcab2
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93326 (2014)
Defining the role of T-cell avidity and killing efficacy in forming immunological response(s), leading to relapse-remission and autoantibody release in autoimmune type 1 diabetes (T1D), remains incompletely understood. Using competition-based populat
Externí odkaz:
https://doaj.org/article/94e395de97ef47dab20d80e37b3fa5b3
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e14796 (2011)
During the progression of the clinical onset of Type 1 Diabetes (T1D), high-risk individuals exhibit multiple islet autoantibodies and high-avidity T cells which progressively destroy beta cells causing overt T1D. In particular, novel autoantibodies,
Externí odkaz:
https://doaj.org/article/caff210a6bf9461994c7f8cca5135621
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11501 (2010)
BackgroundDiabetes costs represent a large burden to both patients and the health care system. However, few studies that examine the economic consequences of diabetes have distinguished between the two major forms, type 1 and type 2 diabetes, despite
Externí odkaz:
https://doaj.org/article/57aec89f168b48408ed6aeadd088181d
Autor:
Massimo Pietropaolo
Publikováno v:
PLoS Medicine, Vol 2, Iss 5, p e140 (2005)
Externí odkaz:
https://doaj.org/article/d465db27f3ac47d49688f3a78c05f321
Autor:
Bryan M. Burt, R. Taylor Ripley, Thomas M. Wheeler, Christopher I. Amos, Farrah Kheradmand, Massimo Pietropaolo, Joel M. Sederstrom, Daniel Y. Wang, Ju-Seog Lee, Sung Yun Jung, Jong Min Choi, Taylor Splawn, Daniela Ramos, Cynthia Y. Truong, Maheshwari Ramineni, Wendong Yu, Hyun-Sung Lee, Hee-Jin Jang
Although the majority of patients with advanced lung adenocarcinoma (LUAD) are eligible to receive immune checkpoint blockade, approximately 80% of these tumors are resistant to this therapeutic approach. Insights at the single-cell level into mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e8c2acd085b3f6a175a773cbf54c18
https://doi.org/10.1158/0008-5472.c.6514119
https://doi.org/10.1158/0008-5472.c.6514119
Autor:
Bryan M. Burt, R. Taylor Ripley, Thomas M. Wheeler, Christopher I. Amos, Farrah Kheradmand, Massimo Pietropaolo, Joel M. Sederstrom, Daniel Y. Wang, Ju-Seog Lee, Sung Yun Jung, Jong Min Choi, Taylor Splawn, Daniela Ramos, Cynthia Y. Truong, Maheshwari Ramineni, Wendong Yu, Hyun-Sung Lee, Hee-Jin Jang
Supplementary Data from Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa2d054a5c579393b1b865940109067
https://doi.org/10.1158/0008-5472.22432503.v1
https://doi.org/10.1158/0008-5472.22432503.v1
Autor:
Type I Diabetes TrialNet Study Group, Massimo Pietropaolo, Patrick W. Nelson, Mark A. Atkinson, Desmond A. Schatz, Michael J. Haller, Sandra M. Lord, Carla J. Greenbaum, Jessica L. Dunne, Kevan C. Herold, Jennifer L. Sherr, Siripoom V. McKay, Madhuri M. Vasudevan, Andrea K. Steck, David Scheinker, Destiny Anyaiwe, Shuai Huang, Maria Acevedo-Calado, Susan L. Pietropaolo, Darrell M. Wilson
OBJECTIVE Continuous glucose monitoring (CGM) parameters may identify subjects at risk of progressing to overt type 1 diabetes. We aimed to determine whether CGM metrics provides additional insights into progression to clinical Stage 3 type 1 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecafda4083adf8e03e15b3babc92b74
https://doi.org/10.2337/figshare.21667085
https://doi.org/10.2337/figshare.21667085