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Autor:
Rosamaria Micheletti, Myrna Gil Quintero, Luciano Maiocchi, Ettore Giraldo, Marco Turconi, Massimo Nicola, Arturo Donetti
Publikováno v:
ChemInform. 22
A series of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid esters and amides containing a basic azacyclo- or azabicycloalkyl moiety has been synthesized and evaluated for 5-HT3 antagonistic activity in a radioligand binding assay ([3H]ICS 20593
Autor:
Arturo Donetti, Antonio Schiavone, Rosella Micheletti, Marco Turconi, Massimo Nicola, Ernesto Montagna, Raffaele Cesana, Angelo Sagrada, C.A. Rizzi
Publikováno v:
European Journal of Pharmacology. 203:203-211
The pharmacological profile of six representative members of a novel class of 5-HT3 receptor antagonists is described. The compounds are esters and amides of benzimidazolone-1-carboxylic acid with a basic azabicycloalkyl moiety (compounds 1-3) and th
Autor:
Rosamaria Micheletti, Massimo Nicola, Marco Turconi, Ettore Giraldo, Myrna Gil Quintero, Arturo Donetti, Luciano Maiocchi
Publikováno v:
Journal of Medicinal Chemistry. 33:2101-2108
A series of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid esters and amides containing a basic azacyclo- or azabicycloalkyl moiety has been synthesized and evaluated for 5-HT3 antagonistic activity in a radioligand binding assay ([3H]ICS 20593
Autor:
Giancarlo, Micheletto, Massimo Nicola, Perrini, Vincenzo, Occhipinti, Boris, Ruggiero, Giuseppe, Fichera, Franco, Di Prisco, Marco Antonio, Zappa, Riccardo, Caccialanza, Santo Bressani, Doldi
Publikováno v:
Annali italiani di chirurgia. 77(4)
Since 1998, we adopted in our clinical practice for obesity treatment the new intragastric balloon (BioEnterics Intragastric Balloon, BIB), it has the characteristics of an "ideal gastric balloon" (Workshop Tarpon Springs, 1987).Since March 1998 we h
Autor:
A. Donetti, A. Sagrada, M. Turconi, Massimo Nicola, E. Montagna, D. R. Algate, Schiantarelli Pierino, R. Micheletti, E. M. Rimoldi, P. Bonali
Publikováno v:
Cancer chemotherapy and pharmacology. 28(6)
The antiemetic activity of DAU 6215, a novel antagonist of 5-HT3 receptors, was investigated in animal models of cytotoxic treatment-evoked emesis and compared with the antiemetic activity of ondansetron and metoclopramide. In dogs, vomiting was indu
Publikováno v:
Journal of Heterocyclic Chemistry. 18:825-828
The synthesis of 4-acyl-2,3-dihydro-4H-1,4-oxazines (6a-h) via acid dehydration of 4-acyl 2- and 3-morpholinols is described. During dehydration of 2-morpholinols 3d,e, N-alkylisoquinolones 7a-e were also isolated.
Autor:
Micheletto G; Dipartimento di Scienze Chirurgiche, Cattedra di Chirurgia Generale dell'Università degli Studi di Milano., Perrini MN, Occhipinti V, Ruggiero B, Fichera G, Di Prisco F, Zappa MA, Caccialanza R, Doldi SB
Publikováno v:
Annali italiani di chirurgia [Ann Ital Chir] 2006 Jul-Aug; Vol. 77 (4), pp. 305-8.