Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Massimo Nichane"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and ar
Externí odkaz:
https://doaj.org/article/8cbd639ed031408ca7c8ee10358e1593
Autor:
Boon-Seng Soh, Shi-Yan Ng, Hao Wu, Kristina Buac, Joo-Hye C. Park, Xiaojun Lian, Jiejia Xu, Kylie S. Foo, Ulrika Felldin, Xiaobing He, Massimo Nichane, Henry Yang, Lei Bu, Ronald A. Li, Bing Lim, Kenneth R. Chien
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Understanding coronary vessels development provides basis for regenerative strategies. Here, Soh et al. identify endothelin-1 as a key molecule driving long-term expansion of ISL1+bipotent vascular progenitors derived from human embryonic stem cells,
Externí odkaz:
https://doaj.org/article/9f548185f9ed4383938465a5168f1c5d
Autor:
Boon-Seng Soh, Shi-Yan Ng, Hao Wu, Kristina Buac, Joo-Hye C. Park, Xiaojun Lian, Jiejia Xu, Kylie S Foo, Ulrika Felldin, Xiaobing He, Massimo Nichane, Henry Yang, Lie Bu, Ronald A Li, Bing Lim, Kenneth R Chien
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7: Article number: 10774 (2016); Published: 8 March 2016; Updated: 19 July 2016. The affiliation details for Boon-Seng Soh, Lei Bu and Ronald A. Li are incorrect in this Article. The correct addresses of these authors are listed
Externí odkaz:
https://doaj.org/article/4e956a7f772741c5afbc122a18d8f823
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and ar
Autor:
Asif Javed, Thomas Lufkin, Massimo Nichane, Sivakamasundari, Petra Kraus, Monisha Ganesan, Lay Teng Ang, Bing Lim, Kyle M. Loh
Publikováno v:
Nature Methods. 14:1205-1212
Multiple adult tissues are maintained by stem cells of restricted developmental potential which can only form a subset of lineages within the tissue. For instance, the two adult lung epithelial compartments (airways and alveoli) are separately mainta
Autor:
Kyle M. Loh, Massimo Nichane
Publikováno v:
Cell Stem Cell
Mbd3, a member of Nucleosome Remodeling and Deacetylase (NuRD) co-repressor complex, was previously identified as an inhibitor for deterministic iPSC reprogramming where up to 100% of donor cells successfully complete the process. NuRD can assume mul
Autor:
Massimo, Nichane, Asif, Javed, V, Sivakamasundari, Monisha, Ganesan, Lay Teng, Ang, Petra, Kraus, Thomas, Lufkin, Kyle M, Loh, Bing, Lim
Publikováno v:
Nature methods. 14(12)
Multiple adult tissues are maintained by stem cells of restricted developmental potential which can only form a subset of lineages within the tissue. For instance, the two adult lung epithelial compartments (airways and alveoli) are separately mainta
Autor:
Elizabeth Ng, Edouard G. Stanley, Vittorio Sebastiano, Bing Lim, Andrew G. Elefanty, Jun Qiang Auyeong, Siew Hua Choo, Kian Leong Lee, Massimo Nichane, Lisa Azzola, Lorenz Poellinger, Jingyao Zhang, Lay Teng Ang, Jens Durruthy-Durruthy, Shyam Prabhakar, Jasmin Ang, Vibhor Kumar, Junru Tan, Kyle M. Loh, Monireh Soroush Noghabi, Christina Ying Yan Lim, Irving L. Weissman, Qingfeng Chen
Publikováno v:
Cell Stem Cell. 14(2):237-252
SummaryHuman pluripotent stem cell (hPSC) differentiation typically yields heterogeneous populations. Knowledge of signals controlling embryonic lineage bifurcations could efficiently yield desired cell types through exclusion of alternate fates. The
Autor:
Lin Lin Su, Sakis Mantalaris, Atasha Asmat, Shi-Yan Ng, Pin Li, Dahai Zheng, Bing Lim, Julie Su Li Yeo, Elaine Hsuen Lim, Boon Seng Soh, Wen Cai Zhang, Jianzhu Chen, Wa Xian, Jia Lu, Frank McKeon, Poo-Sing Wong, Lan Hiong Wong, Massimo Nichane, Henry He Yang, Peng Cheang Wong
Publikováno v:
Molecular Therapy. 20:2335-2346
Previous efforts to derive lung progenitor cells from human embryonic stem (hES) cells using embryoid body formation or stromal feeder cocultures had been limited by low efficiencies. Here, we report a step-wise differentiation method to drive both h
Autor:
Henry Yang, Kenneth R. Chien, Kristina Buac, Hao Wu, Lie Bu, Bing Lim, Shi-Yan Ng, Joo-Hye C. Park, Massimo Nichane, Xiaobing He, Ulrika Felldin, Ronald A. Li, Boon Seng Soh, Jiejia Xu, Kylie S. Foo, Xiaojun Lian
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications
Nature Communications
Coronary arteriogenesis is a central step in cardiogenesis, requiring coordinated generation and integration of endothelial cell and vascular smooth muscle cells. At present, it is unclear whether the cell fate programme of cardiac progenitors to gen