Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Massimo Morfini"'
Autor:
Massimo Morfini, Jacopo Agnelli Giacchiello, Erminia Baldacci, Christian Carulli, Giancarlo Castaman, Anna Chiara Giuffrida, Giuseppe Malcangi, Angiola Rocino, Sergio Siragusa, Ezio Zanon
Publikováno v:
Hematology Reports, Vol 15, Iss 2, Pp 384-397 (2023)
The Medical Directors of nine Italian Hemophilia Centers reviewed and discussed the key issues concerning the replacement therapy of hemophilia patients during a one-day consensus conference held in Rome one year ago. Particular attention was paid to
Externí odkaz:
https://doaj.org/article/d24dcae5a7a04163aca7e5a8789dc405
Autor:
Ippazio Cosimo Antonazzo, Paolo Angelo Cortesi, Ezio Zanon, Samantha Pasca, Massimo Morfini, Cristina Santoro, Raimondo De Cristofaro, Giovanni Di Minno, Paolo Cozzolino, Lorenzo Giovanni Mantovani
Publikováno v:
Medicina, Vol 60, Iss 1, p 34 (2023)
Background and Objectives: This study aimed to assess the effectiveness and costs associated with pharmacokinetics-driven (PK) prophylaxis based on the myPKFiT® device in patients affected by hemophilia A (HA) in Italy. Materials and Methods: An obs
Externí odkaz:
https://doaj.org/article/e55fef36b5b948c8b0130db8da8a903b
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106164- (2020)
The pharmacokinetics data of phase I/II clinical trials (EudraCT Number: 2005-006186-14) of the new, triple inactivated plasma-derived Kedrion FIX concentrate was designed according to the recommendations of SSC-ISTH [1,2]: 11 post-infusion FIX/time
Externí odkaz:
https://doaj.org/article/cf091d166f3a4674a121a9faca0fa0d5
Autor:
Dorina Cultrera, Raimondo De Cristofaro, Paola Giordano, Silvia Linari, Silvia Macchi, Renato Marino, Angelo Claudio Molinari, Angiola Rocino, Cristina Santoro, Piercarla Schinco, Sergio Siragusa, Giuseppe Tagariello, Annarita Tagliaferri, Ezio Zanon, Massimo Morfini
Publikováno v:
Reports, Vol 3, Iss 1, p 3 (2020)
This study aimed to identify the characteristics of patients with hemophilia B eligible for once-weekly treatment with Nonacog alfa. Methods: A survey was conducted in 14 Hemophilia (HCs) of Italy. These centers were given a questionnaire consisting
Externí odkaz:
https://doaj.org/article/ef7cafac02824b77a8a6385ee0114fa9
Autor:
Francesco Rodeghiero, Massimo Morfini, Carlo Nozzoli, Cesare Manotti, Francesco Violi, Giuseppe Castaldo, Fabrizio Pane, Bruno Biasioli, Claudio Velati, on behalf of SISET, AICE, FADOI, FCSA, SIBioC, SIE, SIMeL, SIMI, SIMTI
Publikováno v:
Italian Journal of Medicine, Vol 7, Iss 8S, Pp 71-73 (2013)
Hemorrhagic and thrombotic diseases are highly heterogeneous disorders that may affect a large proportion of the population, as in the case of patients taking antithrombotic drugs. The appropriate management of such conditions requires the availabili
Externí odkaz:
https://doaj.org/article/42a0dff6009b443890f4207b687ef49d
Autor:
Maurizio Margaglione, Giancarlo Castaman, Massimo Morfini, Angiola Rocino, Elena Santagostino, Giuseppe Tagariello, Anna Rita Tagliaferri, Ezio Zanon, Maria Patrizia Bicocchi, Giuseppe Castaldo, Flora Peyvandi, Rosa Santacroce, Francesca Torricelli, Elvira Grandone, Pier Mannuccio Mannucci, the AICE-Genetics Study Group
Publikováno v:
Haematologica, Vol 93, Iss 5 (2008)
Background The high mutational heterogeneity of hemophilia A is a challenge for the provision of genetic services. We plan to identify the mutation in patients with hemophilia A in order to create a confidential national database of mutations for the
Externí odkaz:
https://doaj.org/article/d14e7ea774d344888e0628cf91583a2f
Autor:
Augusto B. Federici, Giancarlo Castaman, Massimo Franchini, Massimo Morfini, Ezio Zanon, Antonio Coppola, Annarita Tagliaferri, Elio Boeri, Maria Gabriella Mazzucconi, Gina Rossetti, Pier Mannuccio Mannucci
Publikováno v:
Haematologica, Vol 92, Iss 7 (2007)
Background and Objectives Plasma-derived concentrates containing von Willebrand factor and factor VIII (VWF/FVIII concentrates) are the mainstay of treatment of patients with inherited von Willebrand’s disease (VWD) who are unresponsive or have a c
Externí odkaz:
https://doaj.org/article/464a6b429be6480b92d55fede46e8826
Autor:
Barbara Lunghi, Massimo Morfini, Nicola Martinelli, Alessio Branchini, Silvia Linari, Giancarlo Castaman, Francesco Bernardi
Publikováno v:
Haemophilia. 29:479-487
Gene variation in receptors for circulating factor VIII (FVIII) is candidate to explain the large inter-patient variability of infused FVIII pharmacokinetics (PK) in haemophilia A (HA).To compare in an Italian HA cohort (n = 26) the influence on FVII
Publikováno v:
Biologics : Targets & Therapy
Progress in hemophilia therapy has been remarkable in the first 20 years of the third millennium, but the innovation began with the description the fractionation of plasma in 1946. The first concentrates followed the discovery of FVIII in the cryopre
Autor:
V. Komrska, Viviane Grassmann, Jan Blatny, Shannon Jackson, Derek Stephens, Massimo Morfini, Julie Curtin, Laura Zunino, Victor S. Blanchette, Ester Zapotocka, Manuel Carcao, Liane Khoo, Margaret L. Rand, Chris Barnes, Gabriela Romanova, David Lillicrap
Publikováno v:
Thrombosis and Haemostasis
Standard pharmacokinetic (PK) assessments are demanding for persons with hemophilia A, requiring a 72-hour washout and 5 to 11 timed blood samples. A no-washout, single-clinic visit, sparse sampling population PK (PPK) protocol is an attractive alter