Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Massimo Mabilia"'
Publikováno v:
ARKIVOC, Vol 2006, Iss 8, Pp 74-82 (2006)
Externí odkaz:
https://doaj.org/article/26e1a37f7c0648bbba89fba65eb521a1
Autor:
Francesca Mancini, Marilena Giannangeli, Mario Pinza, Claudio Milanese, Massimo Mabilia, Carola Marani Toro
Publikováno v:
Biochemical Pharmacology. 58:851-859
Suramin, a symmetrical polysulfonated urea derivative, promotes the dissociation of trimeric human tumor necrosis factor-alpha (TNF-alpha) into biologically inactive subunits and prevents the interaction of TNF-alpha with its cellular receptors. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::875ed35fc905d534d4e6e110ef488791
https://doi.org/10.1016/s0006-2952(99)00150-1
https://doi.org/10.1016/s0006-2952(99)00150-1
Autor:
Giuseppe Picconi, Leandro Baiocchi, Maria Rita Luparini, Massimo Mabilia, Maurizio Magnani, Mauro Tomaselli, Nicola Cazzolla, Marilena Giannangeli
Publikováno v:
Journal of Medicinal Chemistry. 42:336-345
A series of triazolopyridine derivatives (compounds 2a-l) were synthesized in order to explore the effect of modifications of the alkylpiperazine moiety of trazodone (fragment A) on binding affinity for 5HT2A and alpha1 receptors. All of the synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39413fda5a00e0bd1ce61f7a4c3621cf
https://doi.org/10.1021/jm970700n
https://doi.org/10.1021/jm970700n
Autor:
Massimo Mabilia
Chemoinformatica”, o informatica chimica, si riferisce all'uso di “metodi informatici per risolvere problemi chimici”: ha come oggetto ”strutture molecolari” e descrizioni, proprietà e dati ad esse collegate. Grazie a questo volume, pensat
Publikováno v:
Journal of Medicinal Chemistry. 39:3385-3393
A series of 17 beta-(hydrazonomethyl)-5 beta-androstane-3, beta,14 beta-diol derivatives was synthesized and evaluated in the displacement of [3H]ouabain binding from Na+,K(+)-ATPase. The data were explored with multiple linear regression and partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4188bb46c043e8a16da909f049e277a4
https://doi.org/10.1021/jm950806n
https://doi.org/10.1021/jm950806n
Autor:
Massimo Mabilia, Magdalena Bacilieri, Arianna Bassan, Lorenza Broccardo, Elena Fioravanzo, Stefano Moro, Luca Sartori, Matteo Stocchero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eea3da80f5ba0fb9e9f5b925fffa404
https://doi.org/10.1007/978-88-470-2409-0
https://doi.org/10.1007/978-88-470-2409-0
Autor:
Stella Tinelli, Alfonso Pozzan, Massimo Mabilia, Manlio Palumbo, Franco Zunino, Giovanni Capranico
Publikováno v:
Journal of Molecular Biology. 235:1218-1230
To gain further knowledge of the molecular features of topoisomerase II inhibitors required for drug-receptor complex formation, we investigated the conformational drug determinants of the sequence specificities of drug-stimulated DNA cleavage by com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5ad83dce6aea6f7f35ac0ddf6b9609
https://doi.org/10.1006/jmbi.1994.1075
https://doi.org/10.1006/jmbi.1994.1075
Publikováno v:
ChemInform. 27
A series of 17β-(hydrazonomethyl)-5β-androstane-3β,14β-diol derivatives was synthesized and evaluated in the displacement of [3H]ouabain binding from Na+,K+-ATPase. The data were explored with multiple linear regression and partial least-squares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78116e7afc9090f97c7f6635767e30fc
https://doi.org/10.1002/chin.199649210
https://doi.org/10.1002/chin.199649210
Autor:
Giorgio Fedrizzi, Paolo Barassi, Massimo Mabilia, Mauro Gobbini, Alberto Cerri, S. De Munari, Piero Melloni
Publikováno v:
ChemInform. 29
A new three-dimensional model for the relative binding mode of cassaine 1 and digitoxigenin 2 at the digitalis receptor site is proposed on the basis of the structural and conformational similarities among 1, 2 and its 14,15-seco analogues 3 and 4. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a453e60f4b2aeda5a750feb821c241e4
https://doi.org/10.1002/chin.199849237
https://doi.org/10.1002/chin.199849237
Autor:
Emanuela Tassoni, S. Muck, Natalina Dell'uomo, Massimo Mabilia, Arduino Arduini, Mauro Marzi, Patrizia Minetti, Paolo Carminati, Francesco De Angelis, Roberto Conti, Fabrizio Giorgi, Tinti Maria Ornella, Pompeo Pessotto, Fabio Giannessi, Piero Chiodi
Publikováno v:
Journal of medicinal chemistry. 44(15)
A series of carnitine related compounds of general formula XCH(2)CHZRCH(2)Y were evaluated as CPT I inhibitors in intact rat liver (L-CPT I) and heart mitochondria (M-CPT I). Derivative 27 (ZR = -HNSO(2)R, R = C(12), X = trimethylammonium, Y = carbox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3944a4b8351d06eb261699e5a1d3b0
https://pubmed.ncbi.nlm.nih.gov/11448219
https://pubmed.ncbi.nlm.nih.gov/11448219