Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Massimo BARONI"'
Autor:
Monica Cozzi, Mariacristina Failla, Eleonora Gianquinto, Sandra Kovachka, Valeria Buoli Comani, Carlotta Compari, Omar De Bei, Roberta Giaccari, Francesco Marchesani, Marialaura Marchetti, Luca Ronda, Barbara Rolando, Massimo Baroni, Gabriele Cruciani, Barbara Campanini, Stefano Bettati, Serena Faggiano, Loretta Lazzarato, Francesca Spyrakis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Human hemoglobin (Hb) is the preferred iron source of Staphylococcus aureus. This pathogenic bacterium exploits a sophisticated protein machinery called Iron-regulated surface determinant (Isd) system to bind Hb, extract and internalize heme
Externí odkaz:
https://doaj.org/article/f9ef68fdb4844b4a8556175d108cfb76
Autor:
Angela Criscuolo, Palina Nepachalovich, Diego Fernando Garcia-del Rio, Mike Lange, Zhixu Ni, Massimo Baroni, Gabriele Cruciani, Laura Goracci, Matthias Blüher, Maria Fedorova
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Oxidized lipids are prominent bioactive agents, and yet their molecular repertoire remains largely unknown. Here, the authors apply bioinformatics and LC-MS/MS to uncover the diversity and specificity of modified lipids in human blood plasma of lean
Externí odkaz:
https://doaj.org/article/477817a786f34e5cad8e484c8a825880
Autor:
Matteo Bersani, Mariacristina Failla, Filippo Vascon, Eleonora Gianquinto, Laura Bertarini, Massimo Baroni, Gabriele Cruciani, Federica Verdirosa, Filomena Sannio, Jean-Denis Docquier, Laura Cendron, Francesca Spyrakis, Loretta Lazzarato, Donatella Tondi
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1682 (2023)
The worldwide emergence and dissemination of Gram-negative bacteria expressing metallo-β-lactamases (MBLs) menace the efficacy of all β-lactam antibiotics, including carbapenems, a last-line treatment usually restricted to severe pneumonia and urin
Externí odkaz:
https://doaj.org/article/ee36287cbda04f4cacdbee32b86945c1
Autor:
Teresa Gagliardo, Roberta Ruggeri, Andrea Di Paola, Massimo Baroni, Giunio B. Cherubini, Antonella Gallucci, Cristian Falzone, Stefania Trimboli, Andrey Albul, Gualtiero Gandini
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 372-377 (2021)
Abstract Background Muscle cramps (MCs) are prolonged, involuntary, painful muscle contractions characterized by an acute onset and short duration, caused by peripheral nerve hyperactivity. Objectives To provide a detailed description of the clinical
Externí odkaz:
https://doaj.org/article/4e8a60599dc545699a247f70722e52da
Central nervous system metastasis of an intradural malignant peripheral nerve sheath tumour in a dog
Publikováno v:
Open Veterinary Journal, Vol 9, Iss 1, Pp 49-53 (2019)
An 8-year-old French Bulldog was presented with a nonambulatory tetraparesis. Magnetic Resonance showed an intradurally located mass at the level of the right second cervical nerve root. The mass was surgically removed and the dog was ambulatory with
Externí odkaz:
https://doaj.org/article/8bfde2f34fff4ba1821a8a53c94248c9
Autor:
Marika Menchetti, Luisa De Risio, Greta Galli, Giunio Bruto Cherubini, Daniele Corlazzoli, Massimo Baroni, Gualtiero Gandini
Publikováno v:
Veterinary Quarterly, Vol 39, Iss 1, Pp 57-64 (2019)
Background: Pituitary tumours are common neoplasms of the sellar region in small animals. However, detailed information regarding the spectrum and severity of possible neurological signs are lacking. Objective: To retrospectively describe the neurolo
Externí odkaz:
https://doaj.org/article/bb40a4ab89564bb59204e91dbb5b2ebb
Autor:
Domenico Spinelli, Roberta Budriesi, Barbara Cosimelli, Elda Severi, Matteo Micucci, Massimo Baroni, Fabio Fusi, Pierfranco Ioan, Simon Cross, Maria Frosini, Simona Saponara, Rosanna Matucci, Camillo Rosano, Maurizio Viale, Alberto Chiarini, Emanuele Carosati
Publikováno v:
Molecules, Vol 19, Iss 10, Pp 16543-16572 (2014)
As a result of the ring-into-ring conversion of nitrosoimidazole derivatives, we obtained a molecular scaffold that, when properly decorated, is able to decrease inotropy by blocking L-type calcium channels. Previously, we used this scaffold to devel
Externí odkaz:
https://doaj.org/article/ddf26899b337451bb7cef0ca2fc0bb1d
Autor:
Valerio Ferrario, Lydia Siragusa, Cynthia Ebert, Massimo Baroni, Marco Foscato, Gabriele Cruciani, Lucia Gardossi
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109354 (2014)
A new bioinformatic methodology was developed founded on the Unsupervised Pattern Cognition Analysis of GRID-based BioGPS descriptors (Global Positioning System in Biological Space). The procedure relies entirely on three-dimensional structure analys
Externí odkaz:
https://doaj.org/article/31f1055d668640d79442d8bb28e45ea2
Publikováno v:
Chemical Biology & Drug Design. 101:69-86
Proteolysis-targeting chimeras (PROTACs) are novel therapeutics for the treatment of human disease. They exploit the enormous potential of the E3 ligases, a class of proteins that mark a target protein for degradation via the ubiquitin-proteasome sys
Autor:
Lydia Siragusa, Gabriele Menna, Fabrizio Buratta, Massimo Baroni, Jenny Desantis, Gabriele Cruciani, Laura Goracci
Publikováno v:
Journal of Chemical Information and Modeling. 62:2901-2908