Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Massimo, Levrero"'
Autor:
Alexia Paturel, Francesca Casuscelli di Tocco, Delphine Bousquet, Marie-Laure Plissonnier, Xavier Grand, Hyosun Tak, Françoise Berby, Caroline Scholtès, Barbara Testoni, Fabien Zoulim, Massimo Levrero
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101124- (2024)
Background & Aims: Circulating HBV RNAs have been proposed as a biomarker that reflects the transcriptional activity of covalently closed circular DNA (cccDNA) and may help to evaluate HBV treatment activity. Different research assays have been propo
Externí odkaz:
https://doaj.org/article/df2fae496bcf4f019cadd2a168b5de9a
Autor:
Marc Ringelhan, Svenja Schuehle, Maarten van de Klundert, Elena Kotsiliti, Marie-Laure Plissonnier, Suzanne Faure-Dupuy, Tobias Riedl, Sebastian Lange, Karin Wisskirchen, Frank Thiele, Cho-Chin Cheng, Detian Yuan, Valentina Leone, Ronny Schmidt, Juliana Hünergard, Fabian Geisler, Kristian Unger, Hana Algül, Roland M. Schmid, Roland Rad, Heiner Wedemeyer, Massimo Levrero, Ulrike Protzer, Mathias Heikenwalder
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101128- (2024)
Background & Aims: Although most hepatocellular carcinoma (HCC) cases are driven by hepatitis and cirrhosis, a subset of patients with chronic hepatitis B develop HCC in the absence of advanced liver disease, indicating the oncogenic potential of hep
Externí odkaz:
https://doaj.org/article/ffc2a796c409435a93822963b60ef4ed
Autor:
Claudio Pulito, Federica Mori, Andrea Sacconi, Frauke Goeman, Maria Ferraiuolo, Patrizia Pasanisi, Carlo Campagnoli, Franco Berrino, Maurizio Fanciulli, Rebecca J. Ford, Massimo Levrero, Natalia Pediconi, Ludovica Ciuffreda, Michele Milella, Gregory R. Steinberg, Mario Cioce, Paola Muti, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/501e7d37afcc4aa583a480148d920162
Autor:
Armando Andres Roca Suarez, Marie-Laure Plissonnier, Maud Michelet, Anaëlle Dubois, Sarah Heintz, Maria Saez-Palma, Marion Delphin, Isabelle Bordes, Jennifer Molle, Audrey Diederichs, Mélanie Rodà, Emmanuel Combe, Léa Mougené, Guillaume Giraud, Xavier Grand, Michel Rivoire, Massimo Levrero, Barbara Testoni, Fabien Zoulim
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103359- (2024)
Summary: The liver microenvironment contains a wide variety of monocyte and macrophage populations. Here, we present a protocol for the specific isolation of liver-resident macrophages, known as Kupffer cells (KCs), from human liver resections. We de
Externí odkaz:
https://doaj.org/article/252542b9b4134b41be7a86861021ea81
Autor:
Zhili Li, Claude Caron de Fromentel, Woojun Kim, Wen-Hung Wang, Jiazeng Sun, Bingyu Yan, Sagar Utturkar, Nadia Atallah Lanman, Bennett D. Elzey, Yoon Yeo, Hao Zhang, Majid Kazemian, Massimo Levrero, Ourania Andrisani
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Reduced expression of the RNA helicase DDX5 associated with increased hepatocellular carcinoma (HCC) tumor grade and poor patient survival following treatment with sorafenib. While immunotherapy is the first-line treatment for HCC, sorafenib
Externí odkaz:
https://doaj.org/article/3768119de0414d8a98fbd38fbf6f6e99
Autor:
Mario Cioce, Maria Rita Fumagalli, Sara Donzelli, Frauke Goeman, Valeria Canu, Daniela Rutigliano, Giulia Orlandi, Andrea Sacconi, Claudio Pulito, Alina Catalina Palcau, Maurizio Fanciulli, Aldo Morrone, Maria Grazia Diodoro, Marco Caricato, Anna Crescenzi, Martina Verri, Vito Michele Fazio, Stefano Zapperi, Massimo Levrero, Sabrina Strano, Gian Luca Grazi, Caterina La Porta, Giovanni Blandino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Approximately 20–50% of patients presenting with localized colorectal cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is a major prognostic determinant. Here, we have interrogated a het
Externí odkaz:
https://doaj.org/article/a12078091db24f6e823473565b12efbf
Autor:
Barbara Testoni, Armando Andres Roca Suarez, Arianna Battisti, Marie-Laure Plissonnier, Marintha Heil, Thierry Fontanges, François Villeret, Yasmina Chouik, Massimo Levrero, Upkar Gill, Patrick Kennedy, Fabien Zoulim
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100841- (2023)
Background & Aims: Finite duration of treatment associated with HBsAg loss is the current goal for improved therapeutic approaches against chronic HBV infection, as it indicates elimination or durable inactivation of intrahepatic covalently closed ci
Externí odkaz:
https://doaj.org/article/0821224364c24111a53006fcc65a7417
Autor:
Yasmina Chouik, Fanny Lebossé, Marie-Laure Plissonnier, Jean-Christophe Lega, Pierre Pradat, Teresa Antonini, Miroslava Subic, Kerstin Hartig-Lavie, Domitille Erard, François Villeret, Céline Guichon, Audrey Payancé, Sylvie Radenne, Pierre-Emmanuel Rautou, Fabien Zoulim, Massimo Levrero
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107427- (2023)
Summary: Bacterial infections are the most frequent precipitating event in patients with acute decompensation of cirrhosis (AD) and are associated with high mortality. Early diagnosis is challenging due to cirrhosis-related systemic inflammation. Her
Externí odkaz:
https://doaj.org/article/681a2a68d7d84002818a7c1dd208e296
Autor:
François Villeret, Fanny Lebossé, Sylvie Radenne, Didier Samuel, Bruno Roche, Jean-Yves Mabrut, Vincent Leroy, Georges-Philippe Pageaux, Rodolphe Anty, Sylvie Thevenon, Sinafa Si Ahmed, Aaron Hamilton, Marintha Heil, Caroline Scholtès, Massimo Levrero, Barbara Testoni, Fabien Zoulim, Françoise Berby, Isabelle Bordes, Daniel Cherqui, Tarek Debs, Christian Ducerf, Jean-Charles Duclos-Valle, Marie-Noëlle Hilleret, Antonio Iannelli, Kayvan Mohkam, Francis Navarro
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100728- (2023)
Background & Aims: Prophylaxis with nucleos(t)ide analogues (NUCs) and hepatitis B immunoglobulin (HBIG) has decreased the rate of HBV recurrence after orthotopic liver transplantation (OLT), but the duration of this prophylaxis remains debated. Our
Externí odkaz:
https://doaj.org/article/d2cdbc7e25c84444b623acb9ace8575b
Autor:
Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 523-542 (2021)
Persistent mortality rates of medulloblastoma (MB) and severe side effects of the current therapies require the definition of the molecular mechanisms that contribute to tumor progression. Using cultured MB cancer stem cells and xenograft tumors gene
Externí odkaz:
https://doaj.org/article/3ec33b21a6324dbd9f6e0a27e592e22c