Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Massimo, Gennarelli"'
Autor:
Rosana Carvalho Silva, Paolo Martini, Christa Hohoff, Stefania Mattevi, Marco Bortolomasi, Maria Abate, Valentina Menesello, Massimo Gennarelli, Bernhard T. Baune, Alessandra Minelli
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Electroconvulsive therapy (ECT) benefits patients with treatment-resistant depression (TRD), but the underlying biological processes are unclear. We conducted an epigenome-wide association study in 32 TRD patients undergoing ECT t
Externí odkaz:
https://doaj.org/article/031dcce795c94b22a5850eeb4717c714
Autor:
Catia Scassellati, Nadia Cattane, Francesco Benedetti, Tiziana Borsello, Giuseppe Cicala, Massimo Gennarelli, Patrizia Genini, Alessandro Gialluisi, Arianna Giani, Licia Iacoviello, Alessandra Minelli, Edoardo Spina, Benedetta Vai, Erika Vitali, Annamaria Cattaneo
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100886- (2024)
About one third of patients suffering from Major Depressive Disorder (MDD) do not respond to any antidepressant medications and 75% experience relapses and general health deterioration. Importantly, inflammation can contribute to such negative outcom
Externí odkaz:
https://doaj.org/article/e5fab3571a3742abacd8434797d0381e
Autor:
Rosana Carvalho Silva, Paolo Martini, Christa Hohoff, Stefania Mattevi, Marco Bortolomasi, Valentina Menesello, Massimo Gennarelli, Bernhard T. Baune, Alessandra Minelli
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
ABSTRACTBackground: Stressful events increase the risk for treatment-resistant depression (TRD), and trauma-focused psychotherapy can be useful for TRD patients exposed to early life stress (ELS). Epigenetic processes are known to be related to depre
Externí odkaz:
https://doaj.org/article/552a2263556f4a87bd22689f1b7668fc
Autor:
Antonella Ravaggi, Cosetta Bergamaschi, Chiara Galbiati, Laura Zanotti, Aline S. C. Fabricio, Massimo Gion, Elia Cappelletto, Antonette E. Leon, Massimo Gennarelli, Cesare Romagnolo, Giuseppe Ciravolo, Stefano Calza, Eliana Bignotti, Franco Odicino
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2393 (2024)
Background/Objectives: Endometriosis (END) is a painful gynecological condition. Clinical examination, imaging, and laparoscopy can provide a definitive diagnosis of END. Nonetheless, non-invasive biomarkers could help enhance and streamline the diag
Externí odkaz:
https://doaj.org/article/c2da91a5ee11407d86d4f9fede438901
Autor:
Alice Filippini, Elena Cannone, Valentina Mazziotti, Giulia Carini, Veronica Mutti, Cosetta Ravelli, Massimo Gennarelli, Marco Schiavone, Isabella Russo
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 870 (2024)
Leucine-rich repeat kinase-2 (LRRK2), a gene mutated in familial and sporadic Parkinson’s disease (PD), controls multiple cellular processes important for GLIA physiology. Interestingly, emerging studies report that LRRK2 is highly expressed in oli
Externí odkaz:
https://doaj.org/article/dcb905c6d9454efab22485361994a358
Autor:
Bernhard T. Baune, Alessandra Minelli, Bernardo Carpiniello, Martina Contu, Jorge Domínguez Barragán, Chus Donlo, Ewa Ferensztajn-Rochowiak, Rosa Glaser, Britta Kelch, Paulina Kobelska, Grzegorz Kolasa, Dobrochna Kopeć, María Martínez de Lagrán Cabredo, Paolo Martini, Miguel-Angel Mayer, Valentina Menesello, Pasquale Paribello, Júlia Perera Bel, Giulia Perusi, Federica Pinna, Marco Pinna, Claudia Pisanu, Cesar Sierra, Inga Stonner, Viktor T. H. Wahner, Laura Xicota, Johannes C. S. Zang, Massimo Gennarelli, Mirko Manchia, Alessio Squassina, Marie-Claude Potier, Filip Rybakowski, Ferran Sanz, Mara Dierssen
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact. Pharmacotherapy represents the most common option among the first-line treatment choice; however, only about one third of patients res
Externí odkaz:
https://doaj.org/article/ebddcf97a00d4ab893aa34bffa18bb67
Autor:
Stefano Barlati, Alessandra Minelli, Gabriele Nibbio, Lorenzo Bertoni, Nicola Necchini, Stefano Paolini, Alessia Muscarella, Ughetta Bosco Ubertino, Irene Calzavara-Pinton, Antonio Vita, Massimo Gennarelli
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Pharmacological therapy represents one of the essential approaches to treatment of Major Depressive Disorder (MDD). However, currently available antidepressant medications show high rates of first-level treatment non-response, and several attempts ar
Externí odkaz:
https://doaj.org/article/f876b5a699ab43289b4e76896c08d1ef
Autor:
Paolo Enrico, Giuseppe Delvecchio, Nunzio Turtulici, Rosario Aronica, Alessandro Pigoni, Letizia Squarcina, Filippo M. Villa, Cinzia Perlini, Maria G. Rossetti, Marcella Bellani, Antonio Lasalvia, Chiara Bonetto, Paolo Scocco, Armando D'Agostino, Stefano Torresani, Massimiliano Imbesi, Francesca Bellini, Angelo Veronese, Luisella Bocchio-Chiavetto, Massimo Gennarelli, Matteo Balestrieri, Gualtiero I. Colombo, Annamaria Finardi, Mirella Ruggeri, Roberto Furlan, Paolo Brambilla
Publikováno v:
Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100540- (2023)
Nowadays, the lack of quantitative criteria to resolve the diagnostic heterogeneity of psychotic onsets limits the development of safer and more effective treatments. Therefore, the hypothesis to integrate multimodal data to uncover biological subtyp
Externí odkaz:
https://doaj.org/article/32ac23fa57f6486fb7a32cd2fd387422
Autor:
Alessandra Minelli, Stefano Barlati, Erika Vitali, Stefano Bignotti, Vincenzo Dattilo, Giovanni Battista Tura, Elisabetta Maffioletti, Edoardo Giacopuzzi, Vincenza Santoro, Giulia Perusi, Chiara Cobelli, Chiara Magri, Silvia Bonizzato, Luisella Bocchio-Chiavetto, Edoardo Spina, Antonio Vita, Massimo Gennarelli
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Major depressive disorder (MDD) is a common, chronic, debilitating mood disorder that causes serious functional impairment and significantly decreased quality of life. Pharmacotherapy represents the first-line treatment option; ho
Externí odkaz:
https://doaj.org/article/6ad0c3e7914740e486e0b6fa4b29ab0b
Autor:
Veronica Mutti, Giulia Carini, Alice Filippini, Stefania Castrezzati, Lorena Giugno, Massimo Gennarelli, Isabella Russo
Publikováno v:
Cells, Vol 12, Iss 13, p 1799 (2023)
Chronic neuroinflammation plays a crucial role in the progression of several neurodegenerative diseases (NDDs), including Parkinson’s disease (PD) and Alzheimer’s disease (AD). Intriguingly, in the last decade, leucine-rich repeat kinase-2 (LRRK2
Externí odkaz:
https://doaj.org/article/3caa717b46d143a89af8f4c294402812