Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Massimilliano Pagani"'
Autor:
Nicola Gagliani, Mauro Bombaci, Pl Meroni, JP van Hamburg, Paola Larghi, Sergio Abrignani, Roberto Caporali, B. Karnani, Massimilliano Pagani, Chiara Cordiglieri, Maria Gerosa, Lorenza Maria Argolini, Roberta Gualtierotti, Sander W. Tas, Fabio Grassi, Federica Facciotti, A.E. Penatti, Richard A. Flavell, Stefano Gatti, Jens Geginat, Chiara Vasco, Yasushi Kobayashi, Lorenzo Pignataro, Roberto Bosotti, Elsa Rottoli, Sara Torretta
Publikováno v:
Annals of the Rheumatic Diseases. 79:337-337
Background:IL-10 plays a key role in systemic lupus erythematosus (SLE) pathogenesis, promoting B-cell response. IL10 is mainly secreted by regulatory T-cells, but follicular helper T-cells (TFH), also produce it. We previously identified a subset of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776cafb032ccc674543477b7d18ed7a4
https://doi.org/10.1136/annrheumdis-2020-eular.1532
https://doi.org/10.1136/annrheumdis-2020-eular.1532
Autor:
Jens Geginat, Bodo Steckel, Moira Paroni, Stefano Maglie, Monica Moro, Massimilliano Pagani, Mariacristina Crosti, Sergio Abrignani, Ilko Kastirr
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(8)
IL-17 production defines Th17 cells, which orchestrate immune responses and autoimmune diseases. Human Th17 cells can be efficiently generated with appropriate cytokines from precommitted precursors, but the requirements of uncommitted T cells are st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d961d025742cdb3380fc15a0fd6616ee
https://pubmed.ncbi.nlm.nih.gov/26378072
https://pubmed.ncbi.nlm.nih.gov/26378072
Autor:
Bodo Steckel, Svenja Steinfelder, Stefano Maglie, Elisa Sugliano, Monica Moro, Flavio Caprioli, Fiorenzo Botti, Massimilliano Pagani, K Stölzel, Sergio Abrignani, Jens Geginat, Ilko Kastirr, Maria Cristina Crosti, Moira Paroni, Chiara Romagnani, Giulia Nizzoli, Johanna Sophie Alfen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(7)
IL-21 promotes Th17 differentiation, and Th17 cells that upregulate T-bet, IFN-γ, and GM-CSF drive experimental autoimmune diseases in mice. Anti–IL-21 treatment of autoimmune patients is therefore a therapeutic option, but the role of IL-21 in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68a22d9853d776842c5e9d077fffa61
https://pubmed.ncbi.nlm.nih.gov/25172491
https://pubmed.ncbi.nlm.nih.gov/25172491