Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Massimilliano Mazzone"'
Autor:
Tyler Morrison, Ananda Mirchandani, Emily Watts, Patricia Coelho, Simone Arienti, Joseph Willison, Ailiang Zhang, Manuel Sanchez-Garcia, Pranvera Sadiku, Rebecca Dickinson, Fiona Murphy, Wesley Vermaelen, Amy Lewis, Massimilliano Mazzone, Peter Carmeliet, Christopher Pugh, Patrick Maxwell, Moira Whyte, David Dockrell, Bart Ghesquiere, Sarah Walmsley
Publikováno v:
Wellcome Open Research, Vol 8 (2024)
Background Neutrophils are essential in the early innate immune response to pathogens. Harnessing their antimicrobial powers, without driving excessive and damaging inflammatory responses, represents an attractive therapeutic possibility. The neutrop
Externí odkaz:
https://doaj.org/article/7f20aed589c94a37af77c1597c9f58e5
Autor:
Cormac T. Taylor, Bart Ghesquière, Massimilliano Mazzone, Helen M. Marriott, Veronica Moral, Patrick H. Maxwell, Eilise M. Ryan, Peter Carmeliet, Fiona Murphy, Joseph A Willson, David H. Dockrell, Amy Lewis, Rebecca S. Dickinson, Sarah R. Walmsley, Emily R. Watts, Martin Schneider, A. A. Roger Thompson, Pranvera Sadiku, Christopher W. Pugh, Ananda S. Mirchandani, Christopher J. Schofield, Peter J. Ratcliffe, Edwin R. Chilvers, Alison Harris, Moira K. B. Whyte, David Sammut
Publikováno v:
Sadiku, P, Willson, J A, Dickinson, R, Murphy, F, Harris, A, Lewis, A, Sammut, D, Mirchandani, A S, Ryan, E, Watts, E R, Thompson, A A R, Marriott, H M, Dockrell, D H, Taylor, C T, Schneider, M, Maxwell, P H, Chilvers, E R, Mazzone, M, Moral, V, Pugh, C W, Ratcliffe, P J, Schofield, C J, Ghesquiere, B, Carmeliet, P, Whyte, M K B & Walmsley, S R 2017, ' Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses ', Journal of Clinical Investigation, vol. 127, no. 9, pp. 3407-3420 . https://doi.org/10.1172/JCI90848
The Journal of Clinical Investigation
The Journal of Clinical Investigation
Fully activated innate immune cells are required for effective responses to infection, but their prompt deactivation and removal are essential for limiting tissue damage. Here, we have identified a critical role for the prolyl hydroxylase enzyme Phd2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba6dd30a163120cecfccb56afb32bb9
https://lirias.kuleuven.be/handle/123456789/668098
https://lirias.kuleuven.be/handle/123456789/668098
Autor:
MK Whyte, V Finisguerra, Allan Lawrie, Massimilliano Mazzone, Randall S. Johnson, Julie A. Preston, Adriana Tavares, Aar Thompson, Simon J. Foster, Andrew S. Cowburn, Amy Lewis, Joseph A Willson, Richard R. Meehan, Lynne Williams, David H. Dockrell, Edwin R. Chilvers, Sarah R. Walmsley, Stuart J. Forbes, Abdul G. Hameed, Fiona Murphy, John P. Thomson, Helen M. Marriott, Roland H Stimson, Rebecca S. Dickinson
Publikováno v:
Thorax. 71:A61.2-A62
Introduction Systemic hypoxaemia and recurrent bacterial infections frequently co-exist in patients with acute and chronic lung disease and correlate with poor clinical outcomes. Inappropriate neutrophilic inflammation is regularly seen in these circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e49ac1f90dfb0809bd855883519262f
https://doi.org/10.1136/thoraxjnl-2016-209333.110
https://doi.org/10.1136/thoraxjnl-2016-209333.110