Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Massimiliano Sarra"'
Publikováno v:
Global & Regional Health Technology Assessment, Vol 10, Iss 1 (2023)
The attention paid by regulatory authorities to patient-reported outcomes (PROs) and their related measures (PROMs) has progressively increased to allow for a more complete description of the patient’s health status. This work aimed at investigatin
Externí odkaz:
https://doaj.org/article/10c2d882eb7040c39bd228e59c95ce66
Autor:
Maria Laura Cupi, Massimiliano Sarra, Daniela De Nitto, Eleonora Franzè, Irene Marafini, Ivan Monteleone, Giovanna Del Vecchio Blanco, Omero Alessandro Paoluzi, Davide Di Fusco, Paolo Gentileschi, Angela Ortenzi, Alfredo Colantoni, Francesco Pallone, Giovanni Monteleone
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100980 (2014)
Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage. The factors/mechanisms that sustain and amplify the on
Externí odkaz:
https://doaj.org/article/bc08c54794c340ec9e8d13e3b2012fd6
Autor:
Eleonora Franzè, Roberta Caruso, Carmine Stolfi, Massimiliano Sarra, Maria Laura Cupi, Flavio Caprioli, Ivan Monteleone, Francesca Zorzi, Daniela De Nitto, Alfredo Colantoni, Livia Biancone, Francesco Pallone, Giovanni Monteleone
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69839 (2013)
Monocytes/macrophages displaying different markers of activation/differentiation infiltrate the inflamed gut of patients with inflammatory bowel diseases (IBD), but the role that each monocyte/macrophage subpopulation plays in the pathogenesis of IBD
Externí odkaz:
https://doaj.org/article/6ff59adf9e5b4c9b97f4937ca295baab
Autor:
Francesca Zorzi, Ivan Monteleone, Massimiliano Sarra, Emma Calabrese, Irene Marafini, Micaela Cretella, Silvia Sedda, Livia Biancone, Francesco Pallone, Giovanni Monteleone
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54562 (2013)
OBJECTIVE: Crohn's Disease (CD)-associated inflammation is supposed to be driven by T helper (Th)1/Th17 cell-derived cytokines, even though there is evidence that the mucosal profile of cytokine may vary with the evolution of the disease. We aimed at
Externí odkaz:
https://doaj.org/article/dc5cd45688b84d809df105b16123d396
Autor:
Massimo C. Fantini, Giovanni Monteleone, Francesco Pallone, Thomas T. Macdonald, Markus F. Neurath, Christoph Becker, Daniele Fina, Massimiliano Sarra, Carmine Stolfi, Maximilian J. Waldner, Angelamaria Rizzo
PDF file - 630K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e4924d9c4ea511f7d0a23c68d4ef20
https://doi.org/10.1158/0008-5472.22390118.v1
https://doi.org/10.1158/0008-5472.22390118.v1
Autor:
Massimo C. Fantini, Giovanni Monteleone, Francesco Pallone, Thomas T. Macdonald, Markus F. Neurath, Christoph Becker, Daniele Fina, Massimiliano Sarra, Carmine Stolfi, Maximilian J. Waldner, Angelamaria Rizzo
Patients with inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer due to chronic inflammation. In IBD, chronic inflammation relies upon a TGFβ signaling blockade, but its precise mechanistic relationship to coliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14378551da164e85c9467a0697aea269
https://doi.org/10.1158/0008-5472.c.6502838.v1
https://doi.org/10.1158/0008-5472.c.6502838.v1
Autor:
Arianna Mastrofrancesco, Giovanni Monteleone, Nicaela Aspite, Philippe Chavatte, Pierre Desreumaux, Mauro Picardo, Giorgia Cardinali, Massimiliano Sarra, Daniela Kovacs, Emanuela Camera, Emanuela Bastonini
Publikováno v:
Journal of Investigative Dermatology. 134(4):1001-1011
Peroxisome proliferator-activated receptor γ (PPARγ) antagonizes inflammatory signals by interfering with NF-κB nuclear translocation. Consistently, PPARγ agonists have been proposed in various inflammatory skin disorders, but their wide use has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508424de506ab97baab913ed718effe9
Autor:
Maria Laura Cupi, Alessandra Gambacurta, Flavio Caprioli, Thomas T. MacDonald, Giovanni Monteleone, Roberta Bernardini, Angelamaria Rizzo, Francesco Pallone, Maurizio Mattei, Eleonora Franzè, Marco Maggioni, Marco Ranalli, G. Ronchetti, Ivan Monteleone, Alfredo Colantoni, Massimiliano Sarra
Publikováno v:
Hepatology. 58:1436-1450
Fulminant hepatitis (FH) is a disease characterized by massive destruction of hepatocytes with severe impairment of liver function. The pathogenesis of FH is not fully understood, but hyperactivity of T cells and macrophages with excessive production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fecf1c2de52b2743d8ff800b958f4f7
https://doi.org/10.1002/hep.26446
https://doi.org/10.1002/hep.26446
Publikováno v:
BioFactors. 39:368-373
Interleukin-21 (IL-21), a cytokine produced by various subsets of activated CD4+ T cells, regulates multiple innate and adaptive immune responses. Indeed, IL-21 controls the proliferation and function of CD4+ and CD8+ T lymphocytes, drives the differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::383d4c19fac1a5efaa720f5a70149b43
https://doi.org/10.1002/biof.1105
https://doi.org/10.1002/biof.1105
Publikováno v:
Current Molecular Medicine. 12:592-597
T helper (Th)17 cells and other interleukin (IL)-17-producing cells are supposed to play critical roles in several human immune-mediated diseases, including Crohn's disease (CD) and ulcerative colitis (UC), the main forms of inflammatory bowel diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5106b78d54d7d1d148e083532061a5
https://doi.org/10.2174/156652412800620066
https://doi.org/10.2174/156652412800620066