Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Massimiliano Porrini"'
Autor:
Massimiliano Porrini, Frédéric Rosu, Clémence Rabin, Leonardo Darré, Hansel Gómez, Modesto Orozco, Valérie Gabelica
Publikováno v:
ACS Central Science, Vol 3, Iss 5, Pp 454-461 (2017)
Externí odkaz:
https://doaj.org/article/1f5081ccaa534edf8c9c6a9e4c3bc5fc
Publikováno v:
Journal of The American Society for Mass Spectrometry
Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2020, 31 (10), pp.2035-2043. ⟨10.1021/jasms.0c00060⟩
Journal of The American Society for Mass Spectrometry, 2020, 31 (10), pp.2035-2043. ⟨10.1021/jasms.0c00060⟩
Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2020, 31 (10), pp.2035-2043. ⟨10.1021/jasms.0c00060⟩
Journal of The American Society for Mass Spectrometry, 2020, 31 (10), pp.2035-2043. ⟨10.1021/jasms.0c00060⟩
When electrosprayed from typical native MS solution conditions, RNA hairpins and kissing complexes acquire charge states at which they get significantly more compact in the gas phase than their initial structure in solution. Here, we also show the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a91258d933466f4c6079add5e27ed6f
https://hal.archives-ouvertes.fr/hal-03321844
https://hal.archives-ouvertes.fr/hal-03321844
Publikováno v:
Faraday Discussions
Faraday Discussions, Royal Society of Chemistry, 2018, Advances in ion spectroscopy-from astrophysics to biology, 217, pp.361-382. ⟨10.1039/C8FD00207J⟩
Faraday Discussions, 2018, Advances in ion spectroscopy-from astrophysics to biology, 217, pp.361-382. ⟨10.1039/C8FD00207J⟩
Faraday Discussions, Royal Society of Chemistry, 2018, Advances in ion spectroscopy-from astrophysics to biology, 217, pp.361-382. ⟨10.1039/C8FD00207J⟩
Faraday Discussions, 2018, Advances in ion spectroscopy-from astrophysics to biology, 217, pp.361-382. ⟨10.1039/C8FD00207J⟩
International audience; In solution, UV-vis spectroscopy is often used to investigate structural changes in biomolecules (i.e., nucleic acids), owing to changes in the environment of their chromophores (i.e., the nucleobases). Here we address whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75999a80259ad96a1a7f26e947df867b
https://doi.org/10.26434/chemrxiv.7384868.v1
https://doi.org/10.26434/chemrxiv.7384868.v1
Autor:
Robert C. Tyler, Massimiliano Porrini, Cait E. MacPhee, Perdita E. Barran, Brian F. Volkman, Sophie R. Harvey
Publikováno v:
Harvey, S R, Porrini, M, Tyler, R C, MacPhee, C E, Volkman, B F & Barran, P E 2015, ' Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein ', Physical Chemistry Chemical Physics, vol. 17, no. 16, pp. 10538-10550 . https://doi.org/10.1039/c4cp05136j
Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent. This multi-technique approach has particular applicability for conformationally dynamic systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577b749ad6cfeb36b93592f2ee536472
https://doi.org/10.1039/c4cp05136j
https://doi.org/10.1039/c4cp05136j
Autor:
Massimiliano Porrini, Eric Dausse, Jean-Jacques Toulmé, Clémence Rabin, Josephine Abi-Ghanem, Valérie Gabelica
Publikováno v:
ChemPhysChem
ChemPhysChem, 2017, 18 (19), pp.2782-2790. ⟨10.1002/cphc.201700337⟩
ChemPhysChem, Wiley-VCH Verlag, 2017, 18 (19), pp.2782-2790. ⟨10.1002/cphc.201700337⟩
ChemPhysChem, 2017, 18 (19), pp.2782-2790. ⟨10.1002/cphc.201700337⟩
ChemPhysChem, Wiley-VCH Verlag, 2017, 18 (19), pp.2782-2790. ⟨10.1002/cphc.201700337⟩
International audience; In the RNA realm, non‐Watson Crick base pairs are abundant and affect either the RNA 3D structure and/or its function. Here we investigated the formation of RNA kissing complexes where the loop‐loop interaction is modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935a5322c63c413020c83ed7123c04b8
https://doi.org/10.1002/cphc.201700337
https://doi.org/10.1002/cphc.201700337
Autor:
Perdita E. Barran, Rebecca J. Burnley, Luiz Pedro S. de Carvalho, Richard J. K. Taylor, João Pedro Pisco, Massimiliano Porrini, Victoria Ordsmith, Rachel A. Garlish, Thomas A. Jowitt, Kamila J. Pacholarz, Gerald Larrouy-Maumus
Publikováno v:
Pacholarz, K J, Burnley, R J, Jowitt, T A, Ordsmith, V, Pisco, J P, Porrini, M, Larrouy-Maumus, G, Garlish, R A, Taylor, R J, de Carvalho, L P S & Barran, P E 2017, ' Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase ', Structure (London, England : 1993), vol. 25, no. 5, pp. 730-738 . https://doi.org/10.1016/j.str.2017.03.005
Structure(London, England:1993)
738.e4
Structure(London, England:1993)
738.e4
Summary MtATP-phosphoribosyltransferase (MtATP-PRT) is an enzyme catalyzing the first step of the biosynthesis of L-histidine in Mycobacterium tuberculosis, and proposed to be regulated via an allosteric mechanism. Native mass spectrometry (MS) revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6a0ccf0d281dbef7023541d901ef70
https://www.research.manchester.ac.uk/portal/en/publications/hybrid-mass-spectrometry-approaches-to-determine-how-lhistidine-feedback-regulates-the-enzyzme-mtatpphosphoribosyltransferase(c91580c8-e753-4acf-ae73-f64ac8047573).html
https://www.research.manchester.ac.uk/portal/en/publications/hybrid-mass-spectrometry-approaches-to-determine-how-lhistidine-feedback-regulates-the-enzyzme-mtatpphosphoribosyltransferase(c91580c8-e753-4acf-ae73-f64ac8047573).html
Autor:
Alistair James Henry, Kamila J. Pacholarz, Massimiliano Porrini, Perdita E. Barran, Rebecca J. Burnley, Richard J. K. Taylor, Rachel A. Garlish
Publikováno v:
Angewandte Chemie. 126:7899-7903
Collision cross-sections (CCS) of immunoglobulins G1 and G4 have been determined using linear drift-tube ion-mobility mass spectrometry. Intact antibodies and Fc-hinge fragments present with a larger range of CCS than proteins of comparable size. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d24eb12fec58682008def0c12ae000
https://doi.org/10.1002/ange.201402863
https://doi.org/10.1002/ange.201402863
Publikováno v:
International Journal of Mass Spectrometry. :8-18
Three ‘model’ proteins of varying molecular mass: lysozyme, cytochrome C, and BPTI are incubated with sodium iodide and following nano-spray ionisation, their gas-phase conformations are determined using drift tube ion mobility mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6983d13cd49b4604e81b4712cd3fdfc
https://doi.org/10.1016/j.ijms.2013.02.005
https://doi.org/10.1016/j.ijms.2013.02.005
Publikováno v:
The Journal of Physical Chemistry Letters. 4:1233-1238
Amyloid fibrils are self-assembled aggregates of polypeptides that are implicated in the development of several human diseases. A peptide derived from amino acids 105-115 of the human plasma protein transthyretin forms homogeneous and well-defined fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b706842e30097798830020a09e1aa049
https://doi.org/10.1021/jz400372u
https://doi.org/10.1021/jz400372u
Autor:
Michael Morris, Penka V. Nikolova, Massimiliano Porrini, Ewa Jurneczko, Faye L. Cruickshank, Perdita E. Barran, David Clarke, Iain D. G. Campuzano
Publikováno v:
Angewandte Chemie International Edition. 52:4370-4374
The tumor suppressor p53 is the most mutated protein in human cancers. It is implicated in lung (70%), colon (60%), and stomach (45%) cancers, respectively. The latest release (R16) of the International Agency for Research on Cancer (IARC) TP53 mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d6a76715f901d47ea753dc372dcd62
https://doi.org/10.1002/anie.201210015
https://doi.org/10.1002/anie.201210015