Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Massimiliano Granaiola"'
Autor:
Aldo Andreani, Massimiliano Granaiola, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi, Giorgio Lenaz, Romana Fato, Christian Bergamini
Publikováno v:
ARKIVOC, Vol 2004, Iss 5, Pp 76-84 (2004)
Externí odkaz:
https://doaj.org/article/3f3c50b4cf2b4babaafb579c67cfda99
Autor:
Aldo Andreani, Massimiliano Granaiola, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi, Gianluca Giorgi, Laura Salvini
Publikováno v:
ARKIVOC, Vol 2002, Iss 11, Pp 32-38 (2002)
Externí odkaz:
https://doaj.org/article/3e0fbd4ec4f84750bf25626c0961c6e8
Autor:
Aldo Andreani, Alessandra Locatelli, Lucilla Varoli, Massimiliano Granaiola, Alberto Leoni, Robert H. Shoemaker, Sudhir Kondapaka, Mirella Rambaldi, Jeffrey S. Smith, Rita Morigi, Dominic A. Scudiero, Deborah A. Lannigan
Publikováno v:
European Journal of Medicinal Chemistry. 46:4311-4323
The activity of a series of imidazo[2,1-b]thiazole guanylhydrazones as inhibitors of p90 ribosomal S6 kinase 2 (RSK2) is described. It was found that a small subset of compounds show both potent inhibition of RSK2 kinase activity and tumor cell growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4c540e95b2c57e655799afa85868cb
https://doi.org/10.1016/j.ejmech.2011.07.001
https://doi.org/10.1016/j.ejmech.2011.07.001
Autor:
Cecilia Prata, Alessandra Locatelli, Alberto Leoni, Cristiana Caliceti, Francesco Vieceli Dalla Sega, Silvia Burnelli, Aldo Andreani, Robert H. Shoemaker, Massimiliano Granaiola, Laura Landi, Rita Morigi, Lucilla Varoli, Mirella Rambaldi
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:3004-3011
This paper reports the synthesis of new derivatives (formed by two indole systems separated by a central moiety) analogous of potent antitumor agents previously described. The activity of the bis-indoles bearing a pyridine core confirms the good resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b20902fb6b4b2b2bac10144da28161
https://doi.org/10.1016/j.bmc.2010.03.063
https://doi.org/10.1016/j.bmc.2010.03.063
Autor:
Massimiliano Granaiola, Emanuela Greco, Aldo Andreani, Silvia Burnelli, Alberto Leoni, Rinaldo Cervellati, Mirella Rambaldi, Alessandra Locatelli, Mauro Andrea Cremonini, Lucilla Varoli, Rita Morigi, Giuseppe Placucci
Publikováno v:
European Journal of Medicinal Chemistry. 45:1374-1378
The reaction between isatin and 2,5-dimethoxyaniline is described. The main product was identified as 3,3-bis(4-amino-2,5-dimethoxyphenyl)-1,3-dihydroindol-2-one. The antioxidant activity of the compounds isolated was evaluated with two methods. Thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9deb13ba8f616bfdae015400d19340
https://doi.org/10.1016/j.ejmech.2009.12.035
https://doi.org/10.1016/j.ejmech.2009.12.035
Autor:
Massimiliano Granaiola, Andrea Bedini, Lucilla Varoli, Alberto Leoni, Alessandra Locatelli, Aldo Andreani, Mirella Rambaldi, Rita Morigi, Silvia Burnelli, Santi Mario Spampinato, Nicola Fazio
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2972-2976
A series of hydrochloride derivatives 2a – 9a and quaternary ammonium derivatives 3b – 9b of diphenidol have been synthesized and characterized in receptor binding and cellular functional assays versus human muscarinic M 1 –M 5 receptors expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b680d763bf1eb2d8802b57377f82bc
https://doi.org/10.1016/j.bmcl.2008.03.061
https://doi.org/10.1016/j.bmcl.2008.03.061
Autor:
Aldo Andreani, Massimiliano Granaiola, Silvia Burnelli, Rita Morigi, Alessandra Locatelli, Massimo Guardigli, Aldo Roda, Alberto Leoni, Mirella Rambaldi, M. Rizzoli, Lucilla Varoli
Publikováno v:
European Journal of Medicinal Chemistry. 43:657-661
The synthesis of a new series of imidazo[2,1-b]thiazole derivatives is described. They were tested as potential acetylcholinesterase and butyrylcholinesterase inhibitors by means of a chemiluminescent microassay. Although most of the new compounds di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ef0c75fbb6878843a3935b6f83810c
https://doi.org/10.1016/j.ejmech.2007.04.018
https://doi.org/10.1016/j.ejmech.2007.04.018
Autor:
Rita Morigi, Aldo Andreani, Massimiliano Granaiola, Christian Bergamini, Mirella Rambaldi, Romana Fato, Alberto Leoni, Giorgio Lenaz, Maurizio Recanatini, Alessandra Locatelli
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:5525-5532
In this work we describe the synthesis of a series of imidazo[2,1- b ]thiazoles and 2,3-dihydroimidazo[2,1- b ]thiazoles connected by means of a methylene bridge to CoQ 0 . These compounds were tested as specific inhibitors of the NADH:ubiquinone red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d00250cd4343357f155ebefce06882
https://doi.org/10.1016/j.bmc.2004.08.012
https://doi.org/10.1016/j.bmc.2004.08.012
Autor:
Massimiliano Granaiola, Giovanna Farruggia, Alessandra Locatelli, Lanfranco Masotti, Alberto Leoni, Rita Morigi, Aldo Andreani, Vida Garaliene, Mirella Rambaldi
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:1121-1128
The synthesis and antitumor activity of a new series of E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones is described. Several compounds were active on the primary test (three human cell lines) and entered the second level (60 human cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853063e122ec3e37b1f3bc100b3b5e2e
https://doi.org/10.1016/j.bmc.2003.11.031
https://doi.org/10.1016/j.bmc.2003.11.031
Autor:
Massimiliano Granaiola, Romana Fato, Alberto Leoni, Rita Morigi, Christian Bergamini, Aldo Andreani, Alessandra Locatelli, Giorgio Lenaz, Mirella Rambaldi
Publikováno v:
ARKIVOC, Vol 2004, Iss 5, Pp 76-84 (2004)
Scopus-Elsevier
Scopus-Elsevier
In this work we describe the synthesis and the biological activity of 2-[(E)-3-(6chloroimidazo[2,1-b]thiazol-5-yl)prop-2-enyl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone i.e. an imidazothiazole derivative connected to the benzoquinone ring of Q0. This c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5215e0c216fa13850e62576dbf0e9218
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0005.508
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0005.508