Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Massimiliano, Baldassarre"'
Autor:
Virtu Solano-Collado, Rosa Angela Colamarino, David A. Calderwood, Massimiliano Baldassarre, Stefania Spanò
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Salmonella Typhi is a human-restricted bacterial pathogen that causes typhoid fever, a life-threatening systemic infection. A fundamental aspect of S. Typhi pathogenesis is its ability to survive in human macrophages but not in macrophages from other
Externí odkaz:
https://doaj.org/article/72a538667f73415bb587daec80cd7ab1
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever, a disease that kills an estimated 200,000 people annually. Previously, we discovered an antimicrobial pathway dependent on Rab32 and BLOC-3 (BRAM) that is critical
Externí odkaz:
https://doaj.org/article/807d15ce803940f7bb7bbd65eb396299
Autor:
Rosa Angela Colamarino, Hongjiao Yu, Massimiliano Baldassarre, Natalia Cattelan, Stefania Spanò, Kornelia Przybyszewska
The Rab32 antimicrobial pathway has been shown to restrict Salmonella Typhi, in mouse macrophages. The broad-host pathogen Salmonella Typhimurium however has evolved a strategy to evade the Rab32 antimicrobial pathway, via its effector protein GtgE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa3f76a36366ecce5cf08e9d7e35877
https://doi.org/10.1101/2020.11.05.369652
https://doi.org/10.1101/2020.11.05.369652
Autor:
Matteo Zanda, Sergio Dall'Angelo, Albert D. Windhorst, Beatrice Longo, Chiara Zanato, Massimiliano Baldassarre, Monica Piras, Danielle J. Vugts
Publikováno v:
Longo, B, Zanato, C, Piras, M, Dall'angelo, S, Windhorst, A D, Vugts, D J, Baldassarre, M & Zanda, M 2020, ' Design, Synthesis, Conjugation, and Reactivity of Novel trans,trans-1,5-Cyclooctadiene-Derived Bioorthogonal Linkers ', Bioconjugate chemistry, vol. 31, no. 9, pp. 2201-2210 . https://doi.org/10.1021/acs.bioconjchem.0c00375
Bioconjugate chemistry, 31(9), 2201-2210. American Chemical Society
Bioconjugate chemistry 31 (2020): 2201–2210. doi:10.1021/acs.bioconjchem.0c00375
info:cnr-pdr/source/autori:Longo B.; Zanato C.; Piras M.; Dall'angelo S.; Windhorst A.D.; Vugts D.J.; Baldassarre M.; Zanda M./titolo:Design, Synthesis, Conjugation, and Reactivity of Novel trans,trans-1,5-Cyclooctadiene-Derived Bioorthogonal Linkers/doi:10.1021%2Facs.bioconjchem.0c00375/rivista:Bioconjugate chemistry/anno:2020/pagina_da:2201/pagina_a:2210/intervallo_pagine:2201–2210/volume:31
Bioconjugate chemistry, 31(9), 2201-2210. American Chemical Society
Bioconjugate chemistry 31 (2020): 2201–2210. doi:10.1021/acs.bioconjchem.0c00375
info:cnr-pdr/source/autori:Longo B.; Zanato C.; Piras M.; Dall'angelo S.; Windhorst A.D.; Vugts D.J.; Baldassarre M.; Zanda M./titolo:Design, Synthesis, Conjugation, and Reactivity of Novel trans,trans-1,5-Cyclooctadiene-Derived Bioorthogonal Linkers/doi:10.1021%2Facs.bioconjchem.0c00375/rivista:Bioconjugate chemistry/anno:2020/pagina_da:2201/pagina_a:2210/intervallo_pagine:2201–2210/volume:31
The tetrazine/trans-cyclooctene (TCO) inverse electron-demand Diels-Alder (IEDDA) reaction is the fastest bioorthogonal "click"ligation process reported to date. In this context, TCO reagents have found widespread applications; however, their availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cea688dac66b42e463022725af2adfb
https://research.vumc.nl/en/publications/5b333705-638d-4eb3-abf3-de1adab5b3a6
https://research.vumc.nl/en/publications/5b333705-638d-4eb3-abf3-de1adab5b3a6
Autor:
Beatrice, Longo, Chiara, Zanato, Monica, Piras, Sergio, Dall'Angelo, Albert D, Windhorst, Danielle J, Vugts, Massimiliano, Baldassarre, Matteo, Zanda
Publikováno v:
Bioconjugate chemistry. 31(9)
The tetrazine/
Publikováno v:
Access Microbiology. 2
Salmonella enterica serovar Typhi (S. Typhi) is a human adapted pathogen and the causative agent of typhoid fever, a life-threatening infection that kills hundred of thousand people every year, being particularly devastating in developing countries.
Autor:
Massimiliano Baldassarre, Ziba Razinia, Clara F Burande, Isabelle Lamsoul, Pierre G Lutz, David A Calderwood
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7830 (2009)
Mammalian filamins (FLNs) are a family of three large actin-binding proteins. FLNa, the founding member of the family, was implicated in migration by cell biological analyses and the identification of FLNA mutations in the neuronal migration disorder
Externí odkaz:
https://doaj.org/article/9450d93359cc4463a14180b8d4b563be
Autor:
Matteo Zanda, Massimiliano Baldassarre, Monica Piras, Manuele Musolino, Sergio Dall'Angelo, Ian N. Fleming, Alessandra Graziadio, Simona Frau
Publikováno v:
Bioconjugate chemistry (Online) 27 (2016): 1332–1340. doi:10.1021/acs.bioconjchem.6b00136
info:cnr-pdr/source/autori:Graziadio A.; Zanda M.; Frau S.; Fleming I.N.; Musolino M.; Dallangelo S.; Baldassarre M.; Piras M./titolo:NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting/doi:10.1021%2Facs.bioconjchem.6b00136/rivista:Bioconjugate chemistry (Online)/anno:2016/pagina_da:1332/pagina_a:1340/intervallo_pagine:1332–1340/volume:27
info:cnr-pdr/source/autori:Graziadio A.; Zanda M.; Frau S.; Fleming I.N.; Musolino M.; Dallangelo S.; Baldassarre M.; Piras M./titolo:NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting/doi:10.1021%2Facs.bioconjchem.6b00136/rivista:Bioconjugate chemistry (Online)/anno:2016/pagina_da:1332/pagina_a:1340/intervallo_pagine:1332–1340/volume:27
Cyclic CNGRC (cCNGRC) peptides are very important targeting ligands for Aminopeptidase N (APN or CD13), which is overexpressed on the surface of many cancer cells. In this work we have (1) developed an efficient solid-phase synthesis and (2) tested o
Autor:
Fang Chen, Xiarong Shi, Leena Kuruvilla, Stephen Viviano, Jamie Bates, Benjamin E. Turk, Massimiliano Baldassarre, David G. Breckenridge, Peng Yue, David Sperandio, Martinez Ruben, Joseph Schlessinger, Valia T. Mihaylova, David A. Calderwood
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Significance Inhibitors of bromodomain and extraterminal domain family proteins (BETi) have generated considerable excitement and are in clinical trials for treatment of several cancers. Cancers treated with targeted therapies eventually become resis