Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

Autor: Cruickshank, Sheena, Mosconi, I., Geuking, M. B., Zaiss, M. M., Massacand, J. C., Aschwanden, C., Kwong Chung, C. K C, Mccoy, K. D., Harris, N. L.

Publikováno v: Mucosal immunology
Cruickshank, S, Mosconi, I, Geuking, M B, Zaiss, M M, Massacand, J C, Aschwanden, C, Kwong Chung, C K C, Mccoy, K D & Harris, N L 2013, ' Intestinal bacteria induce TSLP to promote mutualistic T-cell responses ', Mucosal Immunology, vol. 6, no. 6, pp. 1157-1167 . https://doi.org/10.1038/mi.2013.12
Mucosal Immunology

Thymic stromal lymphopoietin (TSLP) is constitutively expressed in the intestine and is known to regulate inflammation in models of colitis. We show that steady state TSLP expression requires intestinal bacteria and has an important role in limiting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5933830b67a0f9f51d2e2d02b3240131

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

Autor: Massacand, J. C., Stettler, R. C., Meier, R., Humphreys, N. E., Grencis, R. K., Marsland, B. J., Harris, N. L.

Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine, mainly expressed by epithelial cells, and key to the development of allergic responses. The well-documented involvement of TSLP in allergy has led to the conviction that TSLP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______185::78df8f46a43317c9c32adbc02591fc38
https://infoscience.epfl.ch/record/143029

Intestinal Bacteria Condition Dendritic Cells to Promote IgA Production

Autor: Patrick Kaiser, Aubry Tardivel, Nicola L. Harris, Bettina Ernst, Pascal Schneider, Joanna Massacand, Kurt Bürki

Publikováno v: PLoS ONE, 3 (7)
PLoS ONE, Vol 3, Iss 7, p e2588 (2008)
PLoS ONE, vol. 3, no. 7, pp. e2588
PLoS ONE

Immunoglobulin (Ig) A represents the predominant antibody isotype produced at the intestinal mucosa, where it plays an important role in limiting the penetration of commensal intestinal bacteria and opportunistic pathogens. We show in mice that Peyer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e9fb58cfa03282c8b9e4677c2c44b9
https://hdl.handle.net/20.500.11850/69123