Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Masoumeh Sikaroodi"'
Autor:
Claire E. Blanchard, Alison T. Gomeiz, Kyle Avery, Emna El Gazzah, Abduljalil M. Alsubaie, Masoumeh Sikaroodi, Ylenia Chiari, Chelsea Ward, Jonathan Sanchez, Virginia Espina, Emanuel Petricoin, Elisa Baldelli, Mariaelena Pierobon
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Tumor heterogeneity is a main contributor of resistance to anti-cancer targeted agents though it has proven difficult to study. Unfortunately, model systems to functionally characterize and mechanistically study dynamic responses
Externí odkaz:
https://doaj.org/article/c5d264218ccf46bbb36670695390a8aa
Autor:
Jasmohan S Bajaj, Jacqueline G O’Leary, Sofia S Jakab, Andrew Fagan, Masoumeh Sikaroodi, Patrick M Gillevet
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Patients with cirrhosis who have cognitive complaints are presumed to have hepatic encephalopathy (HE), which leads to unwarranted medications while ignoring the underlying disease process causing these complaints. Since neuropsychological testing, t
Externí odkaz:
https://doaj.org/article/dca95f0c579c4958ad69d0158390a12a
Autor:
Thananya Jinato, Masoumeh Sikaroodi, Andrew Fagan, Richard K Sterling, Hannah Lee, Puneet Puri, Brian C Davis, Michael Fuchs, Edith Gavis, Patrick M Gillevet, Jasmohan S Bajaj
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTCognitive dysfunction due to minimal hepatic encephalopathy (MHE) adversely impacts patients with cirrhosis and more precise therapies are needed. Gut-brain axis changes are therapeutic targets, but prior studies have largely focused on bacte
Externí odkaz:
https://doaj.org/article/12e2bb4cf2af4065a1c7352a1baa11ed
Autor:
Jennifer T. Wolstenholme, Justin M. Saunders, Maren Smith, Jason D. Kang, Phillip B. Hylemon, Javier González-Maeso, Andrew Fagan, Derrick Zhao, Masoumeh Sikaroodi, Jeremy Herzog, Amirhossein Shamsaddini, Marcela Peña-Rodríguez, Lianyong Su, Yun-Ling Tai, Jing Zheng, Po-Cheng Cheng, R. Balfour Sartor, Patrick M. Gillevet, Huiping Zhou, Jasmohan S. Bajaj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Gut microbiota composition is altered in patients with alcohol use disorder, and fecal microbiota transplant reduced alcohol craving in patients with alcohol use disorder and liver cirrhosis in a phase 1 clinical trial. Here the authors used stool sa
Externí odkaz:
https://doaj.org/article/71cd530afe02445e92a5c780310d4264
Autor:
Sonya G. Zawada, Michael E. von Fricken, Thomas A. Weppelmann, Masoumeh Sikaroodi, Patrick M. Gillevet
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Outer surface protein C (OspC) is a commonly used marker in population studies of Borreliella to differentiate types and establish evolution over time. Investigating the ospC genetic types of Borreliella burgdorferi across multiple organ tissues of w
Externí odkaz:
https://doaj.org/article/a841dcefe1b441208adc95a67f518c77
Autor:
Jasmohan S. Bajaj, Amirhossein Shamsaddini, Andrew Fagan, Richard K. Sterling, Edith Gavis, Alexander Khoruts, Michael Fuchs, Hannah Lee, Masoumeh Sikaroodi, Patrick M. Gillevet
Publikováno v:
Hepatology Communications, Vol 5, Iss 2, Pp 258-271 (2021)
Antibiotic resistance leads to poor outcomes in cirrhosis. Fecal microbiota transplant (FMT) is associated with reduction in antibiotic resistance gene (ARG) burden in patients without cirrhosis; however, the impact in cirrhosis is unclear. We aimed
Externí odkaz:
https://doaj.org/article/dc398ecf9c9847169a2a41fe9ca127f4
Autor:
Yuan Zhang, Jason D. Kang, Derrick Zhao, Siddartha S. Ghosh, Yanyan Wang, Yunling Tai, Javier Gonzalez-Maeso, Masoumeh Sikaroodi, Patrick M. Gillevet, H. Robert Lippman, Phillip B. Hylemon, Huiping Zhou, Jasmohan S. Bajaj
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundCirrhosis and hepatic encephalopathy (HE) are linked with an altered gut-liver-brain axis, however, the relative contribution of hepatic vagal innervation is unclear. We aimed to determine the impact of hepatic vagotomy on the gut microbiom
Externí odkaz:
https://doaj.org/article/88a0eab8c12b4e55977c23ab76ba90da
Autor:
Jasmohan S Bajaj, Amirhossein Shamsaddini, Andrew Fagan, Sara McGeorge, Edith Gavis, Masoumeh Sikaroodi, Lisa A. Brenner, James B Wade, Patrick M Gillevet
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Most cirrhosis etiologies, such as alcohol, hepatitis C, and obesity, involve behavior that require the loss of inhibitory control. Once cirrhosis develops, patients can also develop cognitive impairment due to minimal hepatic encephalopathy (MHE). B
Externí odkaz:
https://doaj.org/article/2c69a7f4ab89445bac97fd9168744dd2
Autor:
Jasmohan S Bajaj, Amirhossein Shamsaddini, Chathur Acharya, Andrew Fagan, Masoumeh Sikaroodi, Edith Gavis, Sara McGeorge, Alexander Khoruts, Michael Fuchs, Richard K Sterling, Hannah Lee, Patrick M Gillevet
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Background & Aims Altered gut microbiota is associated with poor outcomes in cirrhosis, including infections and hepatic encephalopathy (HE). However, the role of bacterial virulence factors (VFs) is unclear. Aim: Define association of VFs with cirrh
Externí odkaz:
https://doaj.org/article/ff88e34907614f2796426c1ee8a5b73b
Optimization of tissue sampling for Borrelia burgdorferi in white-footed mice (Peromyscus leucopus).
Autor:
Sonya G Zawada, Michael E von Fricken, Thomas A Weppelmann, Masoumeh Sikaroodi, Patrick M Gillevet
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226798 (2020)
Peromyscus leucopus (the white-footed mouse) is a known reservoir of the Lyme disease spirochete Borrelia burgdorferi. Sampling of white-footed mice allows for year-round B. burgdorferi surveillance as well as opportunities to establish the diversity
Externí odkaz:
https://doaj.org/article/2fe0f4d0f304468fa618fc6b5277110d