Výsledky vyhledávání - "Masoud Abdous"

Efficacy assessment of a triple anthrax chimeric antigen as a vaccine candidate in guinea pigs: challenge test with Bacillus anthracis 17 JB strain spores

Autor: Sadegh Hasannia, Seyed-Shahryar Arab, Masoud Abdous, Ali Hatef Salmanian

Publikováno v: Immunopharmacology and Immunotoxicology. 43:495-502

Context Bacillus anthracis secretes a tripartite toxin comprising protective antigen (PA), edema factor (EF), and lethal factor (LF). The human anthrax vaccine is mainly composed of the anthrax protective antigen (PA). Considerable efforts are being

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a2983babd8d12a29be925c0e3c61917
https://doi.org/10.1080/08923973.2021.1945087

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Efficacy assessment of a triple anthrax chimeric antigen as a vaccine candidate in guinea pigs: challenge test with

Autor: Masoud, Abdous, Sadegh, Hasannia, Ali Hatef, Salmanian, Seyed-Shahryar, Arab

Publikováno v: Immunopharmacology and immunotoxicology. 43(4)

In this study, a triple chimeric antigen referred to as ELP (gene accession no: MT590758) comprising highly immunogenic domains of PA, LF, and EF was designed, constructed, and assessed for the immunization capacity against anthrax in a guinea pig mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::abd03c6827ad7842f82ea380131a364e
https://pubmed.ncbi.nlm.nih.gov/34259590

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A new triple chimeric protein as a high immunogenic antigen against anthrax toxins: theoretical and experimental analyses

Autor: Abbas Shali, Ghorban Ali Alizadeh, Seyed Shahryar Arab, Sadegh Hasannia, Abolfazl Khafri, Ammar Mohseni, Masoud Abdous, Afshin Hajizadeh, Ali Hatef Salmanian

Publikováno v: Immunopharmacology and Immunotoxicology. 41:25-31

Background: Anthrax is a zoonotic disease caused by Bacillus anthracis and it can be deadly in 6 days. Considerable efforts have been conducted toward developing more effective veterinary and human...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66e64cf9e2d011becf4d9a40bf7ad26
https://doi.org/10.1080/08923973.2018.1510419

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Generation and screening of efficient neutralizing single domain antibodies (VHHs) against the critical functional domain of anthrax protective antigen (PA)

Autor: Abbas Shali, Fatemeh Gashtasbi, Sadegh Hasannia, Shirin Jalili, S. Shirin Shahangian, Masoud Abdous

Publikováno v: International Journal of Biological Macromolecules. 114:1267-1278

Since anthrax is an acute infectious disease, detection and neutralization of the toxins of pathogenic Bacillus anthracis are of great importance. The critical role of protective antigen (PA) component of tripartite anthrax toxin in toxin entry into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99412007e4e889f9dd143d2a10ab6b38
https://doi.org/10.1016/j.ijbiomac.2018.03.034

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