Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Masoomeh Eskandari"'
Autor:
Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohammad Hasan Jamei, Alireza Poustforoosh, Somayeh Nazari, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triaz
Externí odkaz:
https://doaj.org/article/b3857a4241ff4145bf0fa7257831487f
Autor:
Motahareh Mortazavi, Masoomeh Eskandari, Fatemeh Moosavi, Tahereh Damghani, Mehdi Khoshneviszadeh, Somayeh Pirhadi, Luciano Saso, Najmeh Edraki, Omidreza Firuzi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Oncogenic activation of receptor tyrosine kinases (RTKs) such as MET is associated with cancer initiation and progression. We designed and synthesized a new series of quinazoline derivatives bearing 1,2,3-triazole moiety as targeted anticanc
Externí odkaz:
https://doaj.org/article/c1443f8e9a85470f9474abe6d0ecf7b6
Autor:
Motahareh, Mortazavi, Elaheh, Raufi, Tahereh, Damghani, Mehdi, Khoshneviszadeh, Najmeh, Edraki, Masoomeh, Eskandari, Elisa, Giovannetti, Godefridus J, Peters, Somayeh, Pirhadi, Omidreza, Firuzi
Publikováno v:
European Journal of Pharmacology, 938:175395. Elsevier
Mortazavi, M, Raufi, E, Damghani, T, Khoshneviszadeh, M, Edraki, N, Eskandari, M, Giovannetti, E, Peters, G J, Pirhadi, S & Firuzi, O 2023, ' Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library ', European Journal of Pharmacology, vol. 938, 175395 . https://doi.org/10.1016/j.ejphar.2022.175395
Mortazavi, M, Raufi, E, Damghani, T, Khoshneviszadeh, M, Edraki, N, Eskandari, M, Giovannetti, E, Peters, G J, Pirhadi, S & Firuzi, O 2023, ' Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library ', European Journal of Pharmacology, vol. 938, 175395 . https://doi.org/10.1016/j.ejphar.2022.175395
c-Met receptor tyrosine kinase has recently emerged as an important target with therapeutic implications in pancreatic cancer. In this study, we carried out a docking virtual screening on an in-house library of 441 synthesized compounds and selected
Autor:
Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohamad Hassan Jamei, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triazole moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011f17a1e29ce7078f6026ad978b7188
https://doi.org/10.21203/rs.3.rs-1837075/v1
https://doi.org/10.21203/rs.3.rs-1837075/v1
Publikováno v:
Medical Research Archives. 5
A series of new 4-anilinoquinazoline derivatives (IV-XVI) were synthesized in convenient pathway with desirable yields. 4-Aminoquinazoline derivatives corresponding Erlotinib are more active compounds for inhibition of the epidermal growth factor rec