Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mason X. Zhang"'
Publikováno v:
Infection and Immunity. 78:1250-1259
The complement system is important for host resistance to hematogenously disseminated candidiasis. However, modulation of complement activation by cell wall components ofCandida albicanshas not been characterized. Although intact yeast display mannan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7f8e31459b100eecdd51af8b424a1b
https://doi.org/10.1128/iai.00744-09
https://doi.org/10.1128/iai.00744-09
Publikováno v:
Molecular Immunology. 46:473-480
The complement system has an important role in host resistance to systemic candidiasis but regulation of complement activation by Candida albicans remains poorly defined. Previous studies have identified a requirement for naturally occurring antimann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05567a33dbfc16174d20d6621267758d
https://doi.org/10.1016/j.molimm.2008.10.008
https://doi.org/10.1016/j.molimm.2008.10.008
Autor:
Thomas R. Kozel, Mason X. Zhang, Gayle M. Boxx, Carol Ann Itatani, Kerry Robison, Casey T. Nishiya
Publikováno v:
Infection and immunity. 84(2)
Candida albicans is a yeast-like pathogen and can cause life-threatening systemic candidiasis. Its cell surface is enriched with mannan that is resistant to complement activation. Previously, we developed the recombinant human IgG1 antimannan antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d2b3f0d22685b3d52d5b5794da353f
https://pubmed.ncbi.nlm.nih.gov/26573736
https://pubmed.ncbi.nlm.nih.gov/26573736
Autor:
Ashraf S. Ibrahim, Donald C. Sheppard, Alan J. Waring, William Welch, Mason X. Zhang, Michael R. Yeaman, Quynh T. Phan, Scott G. Filler, Yue Fu, John E. Edwards
Publikováno v:
Journal of Biological Chemistry. 279:30480-30489
The human fungal pathogen Candida albicans colonizes and invades a wide range of host tissues. Adherence to host constituents plays an important role in this process. Two members of the C. albicans Als protein family (Als1p and Als5p) have been found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c7a412d1b08c3c141895c55abb83f5
https://doi.org/10.1074/jbc.m401929200
https://doi.org/10.1074/jbc.m401929200
Publikováno v:
Infection and Immunity. 69:7559-7564
Our previous studies showed thatBlastomyces dermatitidisyeast activates the human complement system, leading to deposition of opsonic complement fragments onto the yeast surface. This report examines the influence of altered surface expression of glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf5b7d599176b8618caebcf90338b86
https://doi.org/10.1128/iai.69.12.7559-7564.2001
https://doi.org/10.1128/iai.69.12.7559-7564.2001
Autor:
Gary Peltz, Hong-Hsing Liu, David L. Dill, Scott G. Filler, Mason X. Zhang, Yajing Hu, Norma V. Solis, Gayle M. Boxx, Aimee K. Zaas, Ming Zheng, Quynh T. Phan
Publikováno v:
Infection and immunity. 79(11)
Candida albicans is a fungal pathogen that causes severe disseminated infections that can be lethal in immunocompromised patients. Genetic factors are known to alter the initial susceptibility to and severity of C. albicans infection. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010d13cd07175bbb65ec2698caeff009
https://pubmed.ncbi.nlm.nih.gov/21875959
https://pubmed.ncbi.nlm.nih.gov/21875959
Publikováno v:
Infection and Immunity. 66:6027-6029
Polyclonal antimannan immunoglobulin G (IgG) activates the classical complement pathway and accelerates initiation of the alternative pathway by Canidida albicans . This dual role was assessed for two antimannan IgM monoclonal antibodies (MAbs). MAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e6178efd7689170031e2dc68f7cf8f
https://doi.org/10.1128/iai.66.12.6027-6029.1998
https://doi.org/10.1128/iai.66.12.6027-6029.1998
Autor:
M. Charlotte Bohlman, Paul W. H. I. Parren, Thomas R. Kozel, Carol Ann Itatani, Mason X. Zhang, Stephen St. Jeor, Dennis R. Burton
Mannan is a major cell wall component found in Candida species. Natural antimannan antibody is present in sera from most normal adults, but its role in host resistance to hematogenously disseminated candidiasis is unknown. The purpose of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c41e488dd9f13e8ac2a4a46c1bc2fc
https://europepmc.org/articles/PMC1346657/
https://europepmc.org/articles/PMC1346657/
Autor:
Yongmoon Han, Thomas R. Kozel, Randall S. MacGill, Mason X. Zhang, Jim E. Cutler, Michael C. Carroll
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(3)
The incidence of life-threatening, hematogenously disseminated candidiasis, which is predominantly caused by Candida albicans, parallels the use of modern medical procedures that adversely affect the immune system. Limited antifungal drug choices and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d258e7cf2f07f2ba6780ab37273d08a
https://pubmed.ncbi.nlm.nih.gov/11466376
https://pubmed.ncbi.nlm.nih.gov/11466376
Autor:
Mason X. Zhang, Thomas R. Kozel
Publikováno v:
Infection and immunity. 66(10)
Candida albicans activates the classical and alternative complement pathways, leading to deposition of opsonic complement fragments on the cell surface. Our previous studies found that antimannan immunoglobulin G (IgG) in normal human serum (NHS) all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3ddc36406e0dee7af2bf84ffea694a
https://pubmed.ncbi.nlm.nih.gov/9746588
https://pubmed.ncbi.nlm.nih.gov/9746588