Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mason Trappio"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Methylene blue (MB) is a century-old medicine, a laboratory dye, and recently shown as a premier antioxidant that combats ROS-induced cellular aging in human skins. Given MB’s molecular structure and light absorption properties, we hypothe
Externí odkaz:
https://doaj.org/article/1413f1dd95c34da8bac22324d41508fd
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167454 (2016)
Compelling evidence suggests that defective DNA damage response (DDR) plays a key role in the premature aging phenotypes in Hutchinson-Gilford progeria syndrome (HGPS). Studies document widespread alterations in histone modifications in HGPS cells, e
Externí odkaz:
https://doaj.org/article/a4d7618d4f9a48abaf797ea2c2404417
Autor:
Xiaojing Mao, John P. Fisher, Bhushan Mahadik, Luke W. Koblan, David R. Liu, Kan Cao, Yantenew G. Gete, Mason Trappio
Publikováno v:
Aging Cell
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder with features of accelerated aging. The majority of HGPS cases are caused by a de novo point mutation in the LMNA gene (c.1824C>T; p.G608G) resulting in progerin, a toxic lamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6387edb7cbc2ae2c6718041d219ae67d
https://doi.org/10.1111/acel.13388
https://doi.org/10.1111/acel.13388
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Methylene blue (MB) is a century-old medicine, a laboratory dye, and recently shown as a premier antioxidant that combats ROS-induced cellular aging in human skins. Given MB’s molecular structure and light absorption properties, we hypothesize that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f569af42d3ec579397f3e97ae5baaa
https://doi.org/10.1038/s41598-021-89970-2
https://doi.org/10.1038/s41598-021-89970-2
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167454 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167454 (2016)
Compelling evidence suggests that defective DNA damage response (DDR) plays a key role in the premature aging phenotypes in Hutchinson-Gilford progeria syndrome (HGPS). Studies document widespread alterations in histone modifications in HGPS cells, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6779eeab13e083eb863fa46872c06e08
http://europepmc.org/articles/PMC5131972
http://europepmc.org/articles/PMC5131972