Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mason L. Yeh"'
Kalirin-7 (Kal7) is a Rac1/RhoG GEF and multidomain scaffold localized to the postsynaptic density which plays an important role in synaptic plasticity. Behavioral and physiological phenotypes observed in the Kal7 knockout mouse are quite specific: g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2323cd224795f74be597b04e6bbb160c
https://doi.org/10.21203/rs.3.rs-41613/v2
https://doi.org/10.21203/rs.3.rs-41613/v2
Autor:
Andrew F Ducruet, Brad E Zacharia, Sergey A Sosunov, Paul R Gigante, Mason L Yeh, Justin W Gorski, Marc L Otten, Richard Y Hwang, Peter A DeRosa, Zachary L Hickman, Paulina Sergot, E Sander Connolly
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38664 (2012)
The restoration of blood-flow following cerebral ischemia incites a series of deleterious cascades that exacerbate neuronal injury. Pharmacologic inhibition of the C3a-receptor ameliorates cerebral injury by attenuating post-ischemic inflammation. Re
Externí odkaz:
https://doaj.org/article/86b13f22d9e74f47a810f87d721e7612
Autor:
Mason L, Yeh, Eric S, Levine
Publikováno v:
OBM neurobiology
Autism spectrum disorders (ASDs) are diagnosed on the basis of three behavioral features, namely, (1) deficits in social communication, (2) absence or delay in language and (3) stereotypy. The consensus regarding the neurological pathogenesis of ASDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2112ea2882e85b2f6064ef2d836069a2
https://pubmed.ncbi.nlm.nih.gov/30854511
https://pubmed.ncbi.nlm.nih.gov/30854511
Brain-derived neurotrophic factor (BDNF), traditionally known for promoting neuronal growth and development, is also a modulator of synaptic transmission. In addition to the well-characterized effects at excitatory synapses, BDNF has been shown to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd65df644cb3c23ac99debaf8fea55b
https://europepmc.org/articles/PMC6470051/
https://europepmc.org/articles/PMC6470051/
Publikováno v:
The Journal of Neuroscience. 32:7701-7710
Neurotrophins have been implicated in regulating neuronal differentiation, promoting neuronal survival, and modulating synaptic efficacy and plasticity. The prevailing view is that, depending on the target and mode of action, most neurotrophins can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9460792e72a1dfa6d89bc16dc3c8b18f
https://doi.org/10.1523/jneurosci.0028-12.2012
https://doi.org/10.1523/jneurosci.0028-12.2012
Autor:
Andrew F. Ducruet, Justin W. Gorski, Gregory H. Cohen, E. Sander Connolly, Peter A. DeRosa, Brad E. Zacharia, Paul R. Gigante, Sergey A. Sosunov, Mason L. Yeh
Publikováno v:
Translational Stroke Research. 2:588-599
The complement cascade is a critical mediator of the inflammatory response following cerebral ischemia. Recent work has demonstrated that genetic-deficiency of Mannose-binding lectin(MBL) ameliorates reperfusion injury and improves outcome in the acu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ceee787be44ff06d8a8d41c41ce9da
https://doi.org/10.1007/s12975-011-0104-2
https://doi.org/10.1007/s12975-011-0104-2
Autor:
E. Sander Connolly, Andrew F. Ducruet, Zachary L. Hickman, Mason L. Yeh, Brad E. Zacharia, Bartosz T. Grobelny, Sergey A. Sosunov
Publikováno v:
Experimental Neurology. 219:398-403
Intracerebral hemorrhage (ICH) is the second most common and deadliest form of stroke. Currently, no pharmacologic treatment strategies exist for this devastating disease. Following the initial mechanical injury suffered at hemorrhage onset, secondar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ae13da9374b3ee36caa42d60a4db10
https://doi.org/10.1016/j.expneurol.2009.07.018
https://doi.org/10.1016/j.expneurol.2009.07.018
Autor:
Mason L. Yeh, Brad E. Zacharia, Bartosz T. Grobelny, E. Sander Connolly, Zachary L. Hickman, Andrew F. Ducruet
Publikováno v:
Expert Opinion on Pharmacotherapy. 10:1895-1906
Ischemic stroke remains one of the leading causes of death and disability in the developed world. Despite many promising preclinical results, the only pharmacologic treatments proven effective in improving clinical outcome following ischemic stroke u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a124e0fda0704e2918e2d1e541211e1c
https://doi.org/10.1517/14656560903055095
https://doi.org/10.1517/14656560903055095
Publikováno v:
Cardiovascular Research
Aims The mesenchymal cushions lining the early embryonic heart undergo complex remodelling to form the membranous ventricular septum as well as the atrioventricular and semilunar valves in later life. Disruption of this process underlies the most com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3e32d2e236df0d70c2cfdd34c24f9ff
https://pubmed.ncbi.nlm.nih.gov/25691540
https://pubmed.ncbi.nlm.nih.gov/25691540
Autor:
Mason L. Yeh, Eric S. Levine
Publikováno v:
OBM Neurobiology. :1-1
Autism spectrum disorders (ASDs) are diagnosed on the basis of three behavioral features, namely, (1) deficits in social communication, (2) absence or delay in language and (3) stereotypy. The consensus regarding the neurological pathogenesis of ASDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f6c5a1cc6dc7bee4ac77122c4361ca5
https://doi.org/10.21926/obm.neurobiol.1702005
https://doi.org/10.21926/obm.neurobiol.1702005