Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mason A. Chilmonczyk"'
Autor:
Annie C. Bowles-Welch, Mason A. Chilmonczyk, Austin L. Culberson, Delta Ghoshal, Peter A. Kottke, Andrei G. Fedorov
Publikováno v:
Lab Chip
Real-time, advanced diagnostics of the biochemical state within cells remains a significant challenge for research and development, production, and application of cell-based therapies. The fundamental biochemical processes and mechanisms of action of
Autor:
Hazel Y. Stevens, Peter A. Kottke, Robert E. Guldberg, Mason A. Chilmonczyk, Andrei G. Fedorov
Publikováno v:
Biotechnology and Bioengineering. 116:121-131
Large-scale manufacturing of therapeutic cells requires bioreactor technologies with online feedback control enabled by monitoring of secreted biomolecular critical quality attributes (CQAs). Electrospray ionization mass spectrometry (ESI-MS) is a hi
Autor:
Annie C. Bowles, Austin L. Culberson, Edwin M. Horwitz, Andrei G. Fedorov, Mason A. Chilmonczyk
Publikováno v:
Cytotherapy. 23:S172
Publikováno v:
Cytotherapy. 22:S14-S15
Background & Aim Within any cell culture, especially on the larger scale of commercial bioreactors, there is considerable heterogeneity that directly impacts the final cell product. This variation results in part from the local shear forces experienc
Autor:
Gilad Doron, Peter A. Kottke, Austin L. Culberson, Edwin M. Horwitz, Andrei G. Fedorov, Kelly Leguineche, Robert E. Guldberg, Mason A. Chilmonczyk
Publikováno v:
Biotechnol J
Nascent advanced therapies, including regenerative medicine and cell and gene therapies, rely on the production of cells in bioreactors that are highly heterogeneous in both space and time. Unfortunately, advanced therapies have failed to reach a wid