Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mason Pairish"'
Autor:
Simon, Planken, Douglas C, Behenna, Sajiv K, Nair, Theodore O, Johnson, Asako, Nagata, Chau, Almaden, Simon, Bailey, T Eric, Ballard, Louise, Bernier, Hengmiao, Cheng, Sujin, Cho-Schultz, Deepak, Dalvie, Judith G, Deal, Dac M, Dinh, Martin P, Edwards, Rose Ann, Ferre, Ketan S, Gajiwala, Michelle, Hemkens, Robert S, Kania, John C, Kath, Jean, Matthews, Brion W, Murray, Sherry, Niessen, Suvi T M, Orr, Mason, Pairish, Neal W, Sach, Hong, Shen, Manli, Shi, James, Solowiej, Khanh, Tran, Elaine, Tseng, Paolo, Vicini, Yuli, Wang, Scott L, Weinrich, Ru, Zhou, Michael, Zientek, Longqing, Liu, Yiqin, Luo, Shuibo, Xin, Chengyi, Zhang, Jennifer, Lafontaine
Publikováno v:
Journal of medicinal chemistry. 60(7)
Mutant epidermal growth factor receptor (EGFR) is a major driver of non-small-cell lung cancer (NSCLC). Marketed first generation inhibitors, such as erlotinib, effect a transient beneficial response in EGFR mutant NSCLC patients before resistance me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::424669cfffca599d5b525ea1e0d9fe2e
https://pubmed.ncbi.nlm.nih.gov/28287730
https://pubmed.ncbi.nlm.nih.gov/28287730
Autor:
Hengmiao, Cheng, Sajiv K, Nair, Brion W, Murray, Chau, Almaden, Simon, Bailey, Sangita, Baxi, Doug, Behenna, Sujin, Cho-Schultz, Deepak, Dalvie, Dac M, Dinh, Martin P, Edwards, Jun Li, Feng, Rose Ann, Ferre, Ketan S, Gajiwala, Michelle D, Hemkens, Amy, Jackson-Fisher, Mehran, Jalaie, Ted O, Johnson, Robert S, Kania, Susan, Kephart, Jennifer, Lafontaine, Beth, Lunney, Kevin K-C, Liu, Zhengyu, Liu, Jean, Matthews, Asako, Nagata, Sherry, Niessen, Martha A, Ornelas, Suvi T M, Orr, Mason, Pairish, Simon, Planken, Shijian, Ren, Daniel, Richter, Kevin, Ryan, Neal, Sach, Hong, Shen, Tod, Smeal, Jim, Solowiej, Scott, Sutton, Khanh, Tran, Elaine, Tseng, William, Vernier, Marlena, Walls, Shuiwang, Wang, Scott L, Weinrich, Shuibo, Xin, Haiwei, Xu, Min-Jean, Yin, Michael, Zientek, Ru, Zhou, John C, Kath
Publikováno v:
Journal of medicinal chemistry. 59(5)
First generation EGFR TKIs (gefitinib, erlotinib) provide significant clinical benefit for NSCLC cancer patients with oncogenic EGFR mutations. Ultimately, these patients' disease progresses, often driven by a second-site mutation in the EGFR kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f69cf3e766e492ce164cc24ad82b59de
https://pubmed.ncbi.nlm.nih.gov/26756222
https://pubmed.ncbi.nlm.nih.gov/26756222
Publikováno v:
Journal of the American Chemical Society. 119:5413-5424
This paper reports the development of β-strand mimic B, which duplicates the hydrogen-bonding functionality of one edge of a tetrapeptide β-strand. When attached to a tripeptide by a suitable linking group, β-strand mimic B forms a hydrogen-bonded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f53d9efe10dcd81b10be3b6057f8fda6
https://doi.org/10.1021/ja963843s
https://doi.org/10.1021/ja963843s
Publikováno v:
Chem. Soc. Rev.. 25:401-415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f444a397d861e8ca1707f3d67b7c5b21
https://doi.org/10.1039/cs9962500401
https://doi.org/10.1039/cs9962500401
Autor:
J Jean, Cui, Michele, McTigue, Mitchell, Nambu, Michelle, Tran-Dubé, Mason, Pairish, Hong, Shen, Lei, Jia, Hengmiao, Cheng, Jacqui, Hoffman, Phuong, Le, Mehran, Jalaie, Gilles H, Goetz, Kevin, Ryan, Neil, Grodsky, Ya-li, Deng, Max, Parker, Sergei, Timofeevski, Brion W, Murray, Shinji, Yamazaki, Shirley, Aguirre, Qiuhua, Li, Helen, Zou, James, Christensen
Publikováno v:
Journal of medicinal chemistry. 55(18)
The c-MET receptor tyrosine kinase is an attractive oncology target because of its critical role in human oncogenesis and tumor progression. An oxindole hydrazide hit 6 was identified during a c-MET HTS campaign and subsequently demonstrated to have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a1f02d1e9303662594ecd33cf2f2b98
https://pubmed.ncbi.nlm.nih.gov/22924734
https://pubmed.ncbi.nlm.nih.gov/22924734
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09383e48aec642b429337b41fc2ca4ab
https://doi.org/10.1002/chin.199725297
https://doi.org/10.1002/chin.199725297
Autor:
I. Q. Lee, James S. Nowick, J. W. Ziller, A.J Shaka, Gilbert H. Mackin, Mason Pairish, Eric M. Smith
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6cfb4a7b6c82f980588da0c6f90038
https://doi.org/10.1002/chin.199748329
https://doi.org/10.1002/chin.199748329
Autor:
James S. Nowick, In Quen Lee, Gilbert Mackin, Mason Pairish, A. J. Shaka, Eric M. Smith, Joseph W. Ziller
Publikováno v:
Molecular Design and Bioorganic Catalysis ISBN: 9789401072526
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df4485d32407eb4186625b1df52b817
https://doi.org/10.1007/978-94-009-1679-1_7
https://doi.org/10.1007/978-94-009-1679-1_7
Autor:
J. Jean Cui, Michele McTigue, Mitchell Nambu, Michelle Tran-Dubé, Mason Pairish, Hong Shen, Lei Jia, Hengmiao Cheng, Jacqui Hoffman, Phuong Le, Mehran Jalaie, Gilles H. Goetz, Marcel Koenig, Tomas Vojkovsky, Fang-Jie Zhang, Steven Do, Iriny Botrous, Kevin Ryan, Neil Grodsky, Ya-li Deng, Max Parker, Sergei Timofeevski, Brion W. Murray, Shinji Yamazaki, Shirley Aguirre, Qiuhua Li, Helen Zou, James Christensen
Publikováno v:
Journal of Medicinal Chemistry. 55:10314-10314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f78e6f3462c4016a526dbb0d1acacb23
https://doi.org/10.1021/jm3014647
https://doi.org/10.1021/jm3014647
Autor:
Angelica Linton, Ping Kang, Martha Ornelas, Susan Kephart, Qiyue Hu, Mason Pairish, Ying Jiang, Chuangxing Guo
Publikováno v:
Journal of Medicinal Chemistry; Nov2011, Vol. 54 Issue 21, p7705-7712, 8p