Altered top-down and bottom-up processing of fear conditioning in panic disorder with agoraphobia

Autor: Lueken, U., Straube, B., Reinhardt, I., Maslowski, N. I., Wittchen, H.-U., Ströhle, A., Wittmann, A., Pfleiderer, B., Konrad, C., Ewert, A., Uhlmann, C., Arolt, V., Jansen, A., Kircher, T.

Background: Although several neurophysiological models have been proposed for panic disorder with agoraphobia (PD/AG), there is limited evidence from functional magnetic resonance imaging (fMRI) studies on key neural networks in PD/AG. Fear condition

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Altered top-down and bottom-up processing of fear conditioning in panic disorder with agoraphobia.

Autor: Lueken U; Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Germany., Straube B; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Germany., Reinhardt I; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Germany., Maslowski NI; Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Germany., Wittchen HU; Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Germany., Ströhle A; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Germany., Wittmann A; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Germany., Pfleiderer B; Department of Clinical Radiology, University of Münster, Germany., Konrad C; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Germany., Ewert A; Department of Clinical Radiology, University of Münster, Germany., Uhlmann C; Department of Psychiatry and Psychotherapy, University of Münster, Germany., Arolt V; Department of Psychiatry and Psychotherapy, University of Münster, Germany., Jansen A; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Germany., Kircher T; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Germany.

Publikováno v: Psychological medicine [Psychol Med] 2014 Jan; Vol. 44 (2), pp. 381-94. Date of Electronic Publication: 2013 Apr 23.