Výsledky vyhledávání

Distinct Attenuation Phenotypes Caused by Mutations in the Translational Starting Window of Theiler’s Murine Encephalomyelitis Virus

Autor: Nadine Jarousse, Vadim I. Agol, Ekaterina G. Viktorova, Elena V. Khitrina, Michel Brahic, Evgeny V. Pilipenko, Maslova Sv

Publikováno v: Journal of Virology. 73:3190-3196

Upon initiation of translation of picornavirus RNA, the ribosome is believed to bind the internal ribosome entry site of the template and then to form a productive complex with a downstream RNA segment, the starting window. The presence or absence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb64b8f5502d9c1eec69e6d1a22350ba
https://doi.org/10.1128/jvi.73.4.3190-3196.1999

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Geographical genotypes (geotypes) of poliovirus case isolates from the former Soviet Union: relatedness to other known poliovirus genotypes

Autor: T N Kutateladze, Lipskaya GYu, E A Chervonskaya, G I Belova, Mark A. Pallansch, Olen M. Kew, Vadim I. Agol, Mick N. Mulders, Maslova Sv, S.G. Drozdov

Publikováno v: Journal of General Virology. 76:1687-1699

A 150 nucleotide long region corresponding to adjoining segments of the genes encoding polypeptides VP1 and 2A of 84 poliovirus strains recently isolated from patients with paralytic poliomyelitis over the territory of the former Soviet Union (FSU) w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babbb5ff7abb33b33ea438b8fa9a71a7
https://doi.org/10.1099/0022-1317-76-7-1687

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Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA

Autor: Anatoly P. Gmyl, Evgeny V. Pilipenko, Alexander N. Sinyakov, Maslova Sv, Yuri V. Svitkin, Vadim I. Agol

Publikováno v: Cell. 68:119-131

Initiation of translation on picornavirus RNAs is accomplished through internal binding of ribosomes to a complex cis-acting element. Here we show that efficient function of this element involves two appropriately spaced smaller elements: UUUCC and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf1482e81004181d631da7523b0e2db
https://doi.org/10.1016/0092-8674(92)90211-t

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Coupled mutations in the 5'-untranslated region of the Sabin poliovirus strains during in vivo passages: structural and functional implications

Autor: G. Y. Lipskaya, Olen M. Kew, Evgeny V. Pilipenko, Vadim I. Agol, Baldev K. Nottay, Yuri V. Svitkin, Arkady R. Muzychenko, Maslova Sv

Publikováno v: Virus Research. 21:111-122

All entero- and rhinovirus RNAs sequenced thus far possess A and U residues at positions corresponding to nucleotides 480 and 525, respectively, of poliovirus type 1. These two nucleotides have been proposed previously to form a base pair. The single

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfe4183c788028e9838aa859a00abdc
https://doi.org/10.1016/0168-1702(91)90002-d

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Nonreplicative RNA Recombination in Poliovirus

Autor: Alexander B. Chetverin, Maslova Sv, Anatoly P. Gmyl, Elena V. Khitrina, Vadim I. Agol, Evgeny V. Belousov

Current models of recombination between viral RNAs are based on replicative template-switch mechanisms. The existence of nonreplicative RNA recombination in poliovirus is demonstrated in the present study by the rescue of viable viruses after cotrans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdd911f98f0c5fb2b85a1089ae34c76
https://europepmc.org/articles/PMC112927/

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Cis-element, oriR, involved in the initiation of (-)strand poliovirus RNA: a quasi-globular multi-domain RNA structure maintained by tertiary ('kissing') interactions

Autor: H J Slot, Maslova Sv, Vadim I. Agol, K V Poperechny, Evgeny V. Pilipenko, Willem J. G. Melchers

Publikováno v: EMBO Journal, 15, pp. 5428-5436
EMBO Journal, 15, 5428-5436
EMBO Journal, 15, 19, pp. 5428-5436
ResearcherID

The key steps in the replication of the poliovirus genome, initiation of (-) and (+) strands, require two different cis-acting elements, oriR and oriL, respectively. It has been proposed that the spatial organization of these elements is maintained b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9668b0512886dd4511605854b2e8fae1
https://hdl.handle.net/2066/187925

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Attenuation of Theiler's murine encephalomyelitis virus by modifications of the oligopyrimidine/AUG tandem, a host-dependent translational cis element

Autor: Evgeny V. Pilipenko, Maslova Sv, Vadim I. Agol, Elena V. Khitrina, Anatoly P. Gmyl

A set of Theiler's murine encephalomyelitis virus mutants with engineered alterations in the conserved oligopyrimidine/AUG tandem (E. V. Pilipenko, A. P. Gmyl, S. V. Maslova, G. A. Belov, A. N. Sinyakov, M. Huang, T. D. K. Brown, and V. I. Agol, J. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f078ff49fb3157db03d450cfbb603d1b
https://europepmc.org/articles/PMC188653/

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Functional and genetic plasticities of the poliovirus genome: quasi-infectious RNAs modified in the 5'-untranslated region yield a variety of pseudorevertants

Autor: Evgeny V. Pilipenko, Anatoly P. Gmyl, Maslova Sv, George A. Belov, Vadim I. Agol

Publikováno v: Journal of virology. 67(10)

Poliovirus RNA species with nucleotides 564 to 571 deleted or with a secondary structure domain (positions 564 to 629) replaced by a shorter irregular oligonucleotide have been engineered previously; these RNAs have been considered quasi-infectious (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d021d78c77d08b6e1d67876b934b9c0
https://pubmed.ncbi.nlm.nih.gov/8396686

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Towards identification of cis-acting elements involved in the replication of enterovirus and rhinovirus RNAs: a proposal for the existence of tRNA-like terminal structures

Autor: Alexander N. Sinyakov, Vadim I. Agol, Maslova Sv, Evgeny V. Pilipenko

On the basis of a comparative analysis of published sequences, models for the secondary structure of the 3'-terminal [poly(A)-preceding] untranslated region of the entero- and rhinovirus RNAs were worked out. The models for all these viruses share a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bfab664fb616fae8d01a7cb5b2b13b8
https://europepmc.org/articles/PMC312265/

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Frequent isolation of intertypic poliovirus recombinants with serotype 2 specificity from vaccine-associated polio cases

Autor: R.P. Bercoff, G. Y. Lipskaya, Maslova Sv, S.G. Drozdov, Vadim I. Agol, A.R. Muzychenko, Michele Equestre, O.K. Kutitova

Publikováno v: Journal of medical virology. 35(4)

Five representatives from a collection of 21 Sabin type 2-like poliovirus strains isolated from paralytic poliomyelitis cases in two regions of the USSR have been subjected t o limited nucleotide sequencing. All proved to be intertypic recombinants h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557816de6849ef64e2606417ee9f803f
https://pubmed.ncbi.nlm.nih.gov/1666406

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