Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Masi Koskinen"'
Autor:
Markku S. Kulomaa, Sampo Kukkurainen, Tiina A. Riihimäki, Nitin Agrawal, Masi Koskinen, Mark S. Johnson, Antti Tullila, Niklas Kähkönen, Tomi T. Airenne, Tarja K. Nevanen, Soili I. Lehtonen, Vesa P. Hytönen
Publikováno v:
Lehtonen, S I, Tullila, A, Agrawal, N, Kukkurainen, S, Kähkönen, N, Koskinen, M, Nevanen, T K, Johnson, M S, Airenne, T T, Kulomaa, M S, Riihimäki, T A & Hytönen, V P 2016, ' Artificial avidin-based receptors for a panel of small molecules ', ACS Chemical Biology, vol. 11, no. 1, pp. 211-221 . https://doi.org/10.1021/acschembio.5b00906
Proteins with high specificity, affinity, and stability are needed for biomolecular recognition in a plethora of applications. Antibodies are powerful affinity tools, but they may also suffer from limitations such as low stability and high production
Autor:
Juha A. E. Määttä, Vesa P. Hytönen, Niklas Kähkönen, Markku S. Kulomaa, Soili I. Lehtonen, Hermann J. Gruber, Teemu O. Ihalainen, Masi Koskinen, Chloe Thomson, Sampo Kukkurainen, Dominik Zauner, Barbara Taskinen
Publikováno v:
Bioconjugate chemistry. 25(12)
Switchavidin is a chicken avidin mutant displaying reversible binding to biotin, an improved binding affinity toward conjugated biotin, and low nonspecific binding due to reduced surface charge. These properties make switchavidin an optimal tool in b