Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Mashooq A. Bhat"'
Autor:
Salma Mortada, Khalid Karrouchi, El Hadki Hamza, Afaf Oulmidi, Mashooq Ahamd Bhat, Hassane Mamad, Youssra Aalilou, Smaail Radi, M’hammed Ansar, Azlarab Masrar, My El Abbes Faouzi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In this study, a two pyrazole derivatives; 2-(5-methyl-1H-pyrazole-3-carbonyl)-N-phenylhydrazine-1-carboxamide (Pyz-1) and 4-amino-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol (Pyz-2) were synthesized and characterized by 13C-NMR,
Externí odkaz:
https://doaj.org/article/00cd9bdcca8d434782a5e28f08fad6c8
Autor:
Rubina Munir, Sumera Zaib, Muhammad Zia-ur-Rehman, Hira Javed, Ayesha Roohi, Muhammad Zaheer, Nabiha Fatima, Mashooq Ahmad Bhat, Imtiaz Khan
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
An important component of the pathogenicity of potentially pathogenic bacteria in humans is the urease enzyme. In order to avoid the detrimental impact of ureolytic bacterial infections, the inhibition of urease enzyme appears to be an appealing appr
Externí odkaz:
https://doaj.org/article/db37dfce75d24441902d82a9fa052f26
Autor:
Atteeque Ahmed, Sumera Zaib, Mashooq Ahmad Bhat, Aamer Saeed, Muhammad Zain Altaf, Fatima Tuz Zahra, Ghulam Shabir, Nehal Rana, Imtiaz Khan
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Diabetes mellitus is a multi-systematic chronic metabolic disorder and life-threatening disease resulting from impaired glucose homeostasis. The inhibition of glucosidase, particularly α-glucosidase, could serve as an effective methodology in treati
Externí odkaz:
https://doaj.org/article/c4a345a2e0ff4a9584b05894d828647d
Autor:
Wafaa A. Ewes, Samar S. Tawfik, Aya M. Almatary, Mashooq Ahmad Bhat, Hamed W. El-Shafey, Ahmed A. B. Mohamed, Abdullah Haikal, Mohammed A. El-Magd, Abdullah A. Elgazar, Marwa Balaha, Abdelrahman Hamdi
Publikováno v:
Molecules, Vol 29, Iss 13, p 3186 (2024)
Cancer remains a leading cause of death worldwide, often resulting from uncontrolled growth in various organs. Protein kinase inhibitors represent an important class of targeted cancer therapies. Recently, the kinases BRAF and VEGFR-2 have shown syne
Externí odkaz:
https://doaj.org/article/a4915b3b03014f48954ca3fc6a3d2663
Autor:
Md. Ahad Ali, Humaira Sheikh, Muhammad Yaseen, Md Omar Faruqe, Ihsan Ullah, Neeraj Kumar, Mashooq Ahmad Bhat, Md. Nurul Haque Mollah
Publikováno v:
Molecules, Vol 29, Iss 11, p 2524 (2024)
The outbreak of SARS-CoV-2, also known as the COVID-19 pandemic, is still a critical risk factor for both human life and the global economy. Although, several promising therapies have been introduced in the literature to inhibit SARS-CoV-2, most of t
Externí odkaz:
https://doaj.org/article/1d2879a844f8436faad779fc8090d22b
Autor:
Shimaa A. Abass, Abdullah A. Elgazar, Sanad S. El-kholy, Amal I. El-Refaiy, Reem A. Nawaya, Mashooq Ahmad Bhat, Foad A. Farrag, Abdelrahman Hamdi, Marwa Balaha, Mohammed A. El-Magd
Publikováno v:
Molecules, Vol 29, Iss 9, p 1927 (2024)
Cisplatin is a potent compound in anti-tumor chemotherapy; however, its clinical utility is hampered by dose-limiting nephrotoxicity. This study investigated whether papaverine could mitigate cisplatin-induced kidney damage while preserving its chemo
Externí odkaz:
https://doaj.org/article/dddc57ba5c164803a93112d6914a2584
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 532 (2024)
The tyrosinase enzyme has a vital role in the browning of vegetables and fruits and the biosynthesis of melanin. In this work, we synthesized a diverse library of coumarin–triazole hybrids, and these compounds were characterized by using suitable a
Externí odkaz:
https://doaj.org/article/fdeb521126be454997393e3c79ffa088
Autor:
Abdelrahman Hamdi, Muhammad Yaseen, Wafaa A. Ewes, Mashooq Ahmad Bhat, Noha I. Ziedan, Hamed W. El-Shafey, Ahmed A. B. Mohamed, Mohamed R. Elnagar, Abdullah Haikal, Dina I. A. Othman, Abdullah A. Elgazar, Ahmed H. A. Abusabaa, Kamal S. Abdelrahman, Osama M. Soltan, Mostafa M. Elbadawi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
This research study describes the development of new small molecules based on 2,4-thiazolidinedione (2,4-TZD) and their aldose reductase (AR) inhibitory activities. The synthesis of 17 new derivatives of 2,4-TZDs hybrids was feasible by incorporating
Externí odkaz:
https://doaj.org/article/9193df9945e94f69a17e78e485f83157
Autor:
Sundas Tariq, Fazal Rahim, Hayat Ullah, Maliha Sarfraz, Rafaqat Hussain, Shoaib Khan, Misbah Ullah Khan, Wajid Rehman, Amjad Hussain, Mashooq Ahmad Bhat, Muhammad Kamran Farooqi, Syed Adnan Ali Shah, Naveed Iqbal
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 410 (2024)
Benzimidazole-based pyrrole/piperidine analogs (1–26) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (
Externí odkaz:
https://doaj.org/article/9b3eb65368d14b0aafb27989d703e974
Autor:
Md. Kaderi Kibria, Md. Ahad Ali, Muhammad Yaseen, Imran Ahmad Khan, Mashooq Ahmad Bhat, Md. Ariful Islam, Rashidul Alam Mahumud, Md. Nurul Haque Mollah
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 432 (2024)
SARS-CoV-2 infections, commonly referred to as COVID-19, remain a critical risk to both human life and global economies. Particularly, COVID-19 patients with weak immunity may suffer from different complications due to the bacterial co-infections/sup
Externí odkaz:
https://doaj.org/article/9e700dea4527450d8d895e09ba07734d