Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Masha Karelina"'
Publikováno v:
eLife, Vol 12 (2023)
Computational prediction of protein structure has been pursued intensely for decades, motivated largely by the goal of using structural models for drug discovery. Recently developed machine-learning methods such as AlphaFold 2 (AF2) have dramatically
Externí odkaz:
https://doaj.org/article/3c71f06bb57d4b6fa70600af45b04bfe
Autor:
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R. Palicharla, Samuel P. Berry, Philipp Tschaikner, Dominik Regele, Douglas F. Covey, Eduard Stefan, Debora S. Marks, Jeremy Reiter, Ron O. Dror, Alex S. Evers, Saikat Mukhopadhyay, Aashish Manglik
Publikováno v:
bioRxiv
The orphan G protein-coupled receptor (GPCR) GPR161 is enriched in primary cilia, where it plays a central role in suppressing Hedgehog signaling1. GPR161 mutations lead to developmental defects and cancers2,3,4. The fundamental basis of how GPR161 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0415060b436de23dff5acd054f84dd90
https://europepmc.org/articles/PMC10245861/
https://europepmc.org/articles/PMC10245861/
