Actin cytoskeleton organization in response to integrin-mediated adhesion

Autor: Laura Dolce, Guido Tarone, Cristina Olivo, Paola Defilippi, Lorenzo Silengo, Mascia Venturino

Publikováno v: Microscopy Research and Technique. 47:67-78

Cell matrix adhesion regulates actin cytoskeleton organization through distinct steps, from formation of filopodia and lamellipodia in the early phases of cell adhesion to organization of focal adhesions and stress fibers in fully adherent cells. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87de8b877575fb001a7d228406b30af
https://doi.org/10.1002/(sici)1097-0029(19991001)47:1<67::aid-jemt7>3.0.co

Integrin-Mediated Signal Transduction in Human Endothelial Cells: Analysis of Tyrosine Phosphorylation Events

Autor: Mascia Venturino, Lorenzo Silengo, Chiarella Bozzo, Giovanna Romano, Guido Tarone, Paola Defilippi, Gisella Volpe

Publikováno v: Cell Adhesion and Communication. 2:75-86

Adhesion of human umbilical endothelial cells to fibronectin resulted in increased tyrosine phosphorylation of a group of proteins with molecular mass ranging from 100 to 130 kDa and of a 70 kDa protein. This pattern of tyrosine phosphorylation was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39e345f90c8486640508d503e34a038
https://doi.org/10.3109/15419069409014203

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

Autor: Erik Schaefer, Mascia Venturino, Monica Smeriglio, Carlo Tacchetti, Paolo Gaggini, Laura Beguinot, Elena Bergatto, Laura Moro, Elisabetta Boeri Erba, Guido Tarone, Laura Dolce, Emilia Turco, Lorenzo Silengo, Sara Cabodi, Saverio Francesco Retta, Jasminka Godovac-Zimmermann, Amedeo Conti, Paola Defilippi, Maria Gabriella Giuffrida

Publikováno v: 277 (2002): 9405–9414.
info:cnr-pdr/source/autori:Moro L., Dolce L., Cabodi S., Bergatto E., Boeri Erba E., Smeriglio M., Turco E., Retta S.F., Giuffrida M.G., Venturino M., Godovac-Zimmermann J., Conti A., Schaefer E., Beguinot L., Tacchetti C., Gaggini P., Silengo L., Tarone G., Defilippi P./titolo:Integrin-induced Epidermal Growth Factor (EGF) Receptor Activation Requires c-Src and p130Cas and Leads to Phosphorilation of Specific EGF Receptor Tyrosines/doi:/rivista:/anno:2002/pagina_da:9405/pagina_a:9414/intervallo_pagine:9405–9414/volume:277

Integrin-mediated cell adhesion cooperates with growth factor receptors in the control of cell proliferation, cell survival, and cell migration. One mechanism to explain these synergistic effects is the ability of integrins to induce phosphorylation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99936701d26f9586cb744d2d081e195f
https://pubmed.ncbi.nlm.nih.gov/11756413

p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors

Autor: Saverio Francesco Retta, Guido Tarone, Cristina Olivo, Mascia Venturino, Paola Defilippi, Lorenzo Silengo, Maria Palmieri

Publikováno v: Experimental cell research. 221(1)

p125FAK is a major tyrosine kinase phosphorylated in response to integrin-dependent adhesion. In this study we use vanadate and phenylarsine oxide (PAO), known inhibitors of phosphotyrosine phosphatases (PTPases), as a tool to artificially modulate p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3181c0ed66dd9467c09eaf27984833
https://pubmed.ncbi.nlm.nih.gov/7589239