Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Mascia Amici"'
1
Akademický článek
Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD
Autor: Thomas M. Sanderson, Liam T. Ralph, Mascia Amici, Ai Na Ng, Bong-Kiun Kaang, Min Zhuo, Sang Jeong Kim, John Georgiou, Graham L. Collingridge
Publikováno v: Frontiers in Synaptic Neuroscience, Vol 14 (2022)
In area CA1 of the hippocampus, long-term depression (LTD) can be induced by activating group I metabotropic glutamate receptors (mGluRs), with the selective agonist DHPG. There is evidence that mGluR-LTD can be expressed by either a decrease in the
Externí odkaz: https://doaj.org/article/eacebaceb61d422c8659256a3053ba26
Zobrazit plný text záznamu
2
Akademický článek
The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression
Autor: Thomas M. Sanderson, Clarrisa A. Bradley, John Georgiou, Yun Hwa Hong, Ai Na Ng, Yeseul Lee, Hee-Dae Kim, Doyeon Kim, Mascia Amici, Gi Hoon Son, Min Zhuo, Kyungjin Kim, Bong-Kiun Kaang, Sang Jeong Kim, Graham L. Collingridge
Publikováno v: Cell Reports, Vol 25, Iss 13, Pp 3631-3646.e3 (2018)
Summary: A major mechanism contributing to synaptic plasticity involves alterations in the number of AMPA receptors (AMPARs) expressed at synapses. Hippocampal CA1 synapses, where this process has been most extensively studied, are highly heterogeneo
Externí odkaz: https://doaj.org/article/d290921b5af4434592a52c654baf45fc
Zobrazit plný text záznamu
3
GSK‐3β regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIα
Autor: Robert J P Pope, Clarrisa A. Bradley, Mascia Amici, Adam R. Cole, Graham L. Collingridge, Yeseul Lee
Publikováno v: The European Journal of Neuroscience
Deregulation of GSK‐3β is strongly implicated in a variety of serious brain conditions, such as Alzheimer disease, bipolar disorder and schizophrenia. To understand how GSK‐3β becomes dysregulated in these conditions, it is important to underst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4ba862252ebcaba3b3dcbaccf582ea
https://doi.org/10.1111/ejn.14841
Zobrazit plný text záznamu
4
PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies
Autor: Ahmed H. Al-Amri, Paul Armstrong, Mascia Amici, Clemence Ligneul, James Rouse, Mohammed E. El-Asrag, Andreea Pantiru, Valerie E. Vancollie, Hannah W.Y. Ng, Jennifer A. Ogbeta, Kirstie Goodchild, Jacob Ellegood, Christopher J. Lelliott, Jonathan G.L. Mullins, Amanda Bretman, Ruslan Al-Ali, Christian Beetz, Lihadh Al-Gazali, Aisha Al Shamsi, Jason P. Lerch, Jack R. Mellor, Abeer Al Sayegh, Manir Ali, Chris F. Inglehearn, Steven J. Clapcote
Publikováno v: Al-Amri, A H, Armstrong, P, Amici, M, Ligneul, C, Mellor, J R & Clapcote, S J 2022, ' PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice and Fruit Flies ', Biological Psychiatry, vol. 92, no. 4, pp. 323-334 . https://doi.org/10.1016/j.biopsych.2021.12.017
BackgroundThe discovery of coding variants in genes that confer risk of intellectual disability (ID) is an important step toward understanding the pathophysiology of this common developmental disability.MethodsHomozygosity mapping, whole-exome sequen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c438ba4555785a1f1213cff239036c
https://cronfa.swan.ac.uk/Record/cronfa59175/Download/59175__23886__9c4736e50fd24c30adbf62bd8435ff6d.pdf
Zobrazit plný text záznamu
6
GSK-3β regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIα
Autor: Mascia Amici, Graham L. Collingridge, Robert J P Pope, Yeseul Lee
Understanding the normal functions of GSK-3β in the central nervous system is of major interest because deregulation of this kinase is strongly implicated in a variety of serious brain conditions, such as Alzheimer disease, bipolar disorder and schi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440e017b222ec171833db4443cef1d95
https://doi.org/10.1101/841676
Zobrazit plný text záznamu
7
The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression
Autor: Yun Hwa Hong, Gi Hoon Son, Clarrisa A. Bradley, Mascia Amici, John Georgiou, Doyeon Kim, Min Zhuo, Hee Dae Kim, Graham L. Collingridge, Thomas M. Sanderson, Bong-Kiun Kaang, Sang Jeong Kim, Kyungjin Kim, Ai Na Ng, Yeseul Lee
Publikováno v: Sanderson, T M, Bradley, C A, Georgiou, J, Hong, Y H, Ng, A N, Lee, Y, Kim, H-D, Kim, D, Amici, M, Son, G H, Zhuo, M, Kim, K, Kaang, B-K, Kim, S J & Collingridge, G L 2018, ' The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression ', Cell Reports, vol. 25, no. 13, pp. 3631-3646.e3 . https://doi.org/10.1016/j.celrep.2018.12.010
Cell Reports
Cell Reports, Vol 25, Iss 13, Pp 3631-3646.e3 (2018)
Summary A major mechanism contributing to synaptic plasticity involves alterations in the number of AMPA receptors (AMPARs) expressed at synapses. Hippocampal CA1 synapses, where this process has been most extensively studied, are highly heterogeneou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d7231d2c4ee98f0abce7f42b541ff4
https://research-information.bris.ac.uk/en/publications/11f67362-7802-4e6e-866c-ba2e5a735bc7
Zobrazit plný text záznamu
8
NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity
Autor: Jonathan G. Hanley, Dipen Rajgor, Thomas M. Sanderson, Graham L. Collingridge, Mascia Amici
Publikováno v: Rajgor, D, Sanderson, T, Amici, M, Collingridge, G L & Hanley, J 2018, ' NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity ', EMBO Journal, vol. 37, no. 11, e97943 . https://doi.org/10.15252/embj.201797943
The EMBO Journal
MicroRNAs (miRNAs) repress translation of target mRNAs by associating with Argonaute (Ago) proteins to form the RNA‐induced silencing complex (RISC), underpinning a powerful mechanism for fine‐tuning protein expression. Specific miRNAs are requir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a936e7d889ff1c28e384f949fac541c
https://research-information.bris.ac.uk/ws/files/156205604/embj.201797943.full.pdf
Zobrazit plný text záznamu
9
Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus
Autor: Thomas M. Sanderson, Bong-Kiun Kaang, Pojeong Park, Zuner A. Bortolotto, Min Zhuo, Mascia Amici, Sun-Lim Choi, Graham L. Collingridge
Publikováno v: Park, P, Sanderson, T, Amici, M, Choi, S-L, Bortolotto, Z, Zhuo, M, Kaang, BK & Collingridge, G 2016, ' Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus ', Journal of Neuroscience, vol. 36, no. 2, pp. 622-631 . https://doi.org/10.1523/JNEUROSCI.3625-15.2016
Two forms of NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) at hippocampal CA1 synapses can be distinguished based on their sensitivity to inhibitors of protein kinase A (PKA). The PKA-dependent form requires multiple episodes of high-f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc45673bfd9a628e1e39f03f4522f9d
https://research-information.bris.ac.uk/en/publications/1872446c-82f4-4817-9c3b-781e6edd7eb0
Zobrazit plný text záznamu
10
Differences in kainate receptor involvement in hippocampal mossy fibre long-term potentiation depending on slice orientation
Autor: Sheila L. Dargan, John L. Sherwood, Zuner A. Bortolotto, David E. Jane, David Lodge, Graham L. Collingridge, Georgia R. Culley, Mascia Amici, Stephen M. Fitzjohn
Publikováno v: Neurochemistry International. 61:482-489
Long-term potentiation (LTP) is a well-established experimental model used to investigate the synaptic basis of learning and memory. LTP at mossy fibre - CA3 synapses in the hippocampus is unusual because it is normally N-methyl-d-aspartate (NMDA) re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4603f6c0a346ebea396272e2a8238e1
https://doi.org/10.1016/j.neuint.2012.04.021
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje