Riociguat for the treatment of pulmonary arterial hypertension

Autor: Ghofrani, Ha, Galiè, N, Grimminger, F, Grünig, E, Humbert, M, Jing, Zc, Keogh, Am, Langleben, D, Kilama, Mo, Fritsch, A, Neuser, D, Rubin, Lj, 1 Study Group including Bortman G, Patent, Keogh, A, Kermeen, F, Feenstra, J, Williams, T, Reeves, G, Kilpatrick, D, Lang, I, Kahler, C, Mascherbauer Steringer, R, Vachiery, Jl, Delcroix, M, Meyer, G, Arakaki, J, Santana, M, Waetge, D, Granton, J, Helmersen, D, He, J, Jing, Z, Zhou, D, Huang, Y, Wang, C, Jansa, P, Neilsen Kudsk JE, Hachulla, E, De Groote, P, Frachon, I, Bourdin, A, Pison, C, Bauer, F, Dromer, C, Marquette, Ch, Degano, B, Neurohr, C, Wilkens, H, Hoffken, G, Hoeper, M, Ghofrani, A, Wirtz, H, Rosenkranz, S, Ewert, R, Orfanos, S, Kramer, M, Ben Gal, T, Scelsi, L, Vizza, C, Harari, S, Confalonieri, M, Albera, Carlo, Fukumoto, Y, Sano, M, Hatano, M, Saji, T, Tanaka, S, Takeda, Y, Takehara, K, Matsubara, H, Kihara, Y, Shiohira, Y, Kawai, H, Homma, S, Satoh, T, Tokunaga, T, Ishizaki, T, Diaz, C, Zamudio, T, De Los Rios, M, Estupian, S, Cacho, Jr, Gamba, M, Beckert, L, Torbicki, A, Castro, G, Reis, A, Agapito, A, Martins, S, Kim, H, Lee, S, Chang, H, Song, Y, Chazova, I, Moiseeva, O, Lim, S, Yip, J, Barbera, J, Roman, A, Palma Jdel, C, Reitan, O, Soderberg, S, Jansson, K, Speich, R, Hsu, Hh, Lin, Hy, Cheng, Cc, Phrommintikul, A, Jaimchariyatam, N, Sayin, T, Kultursay, H, Ongen, G, Pepke Zaba, J, Coghlan, G, Peacock, A, Gibbs, J, Wagoner, L, Badesch, D, Frost, A, Hill, N, Allen, R, Waxman, A, Sood, N, Torres, F, Minai, O, Shapiro, S, Klinger, J, Engel, P, Garcia, H, Schuller, D, Poch, D, Rosenzweig, E, Mcconnell, J, Rischard, F, Olschewski, H, Haverkamp, W, Lehmacher, W, Hoischen, S, Collamati, S, Dehay, J, Hallmann, M, Menezes, F.

Riociguat, a soluble guanylate cyclase stimulator, has been shown in a phase 2 trial to be beneficial in the treatment of pulmonary arterial hypertension. METHODS: In this phase 3, double-blind study, we randomly assigned 443 patients with symptomati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a8fd42189d6ac9c1d50e70aff46618
http://hdl.handle.net/2318/152936