Model-Informed Approach to Recommend Burosumab Dosing Regimens for Pediatric and Adult Patients With the Ultrarare Disease Tumor-Induced Osteomalacia.

Autor: Hruska MW; Kyowa Kirin Inc., Princeton, New Jersey, USA., Sid-Otmane L; Certara Drug Development Solutions, Princeton, New Jersey, USA., Gosselin NH; Certara Drug Development Solutions, Princeton, New Jersey, USA., Quattrocchi E; Kyowa Kirin Pharmaceutical Development Ltd, Marlow, UK., Lee SK; Morphic Therapeutic, Waltham, Massachusetts, USA., Mascelli MA; Chinook Therapeutics Inc, Seattle, Washington, USA., Mehta K; Kyowa Kirin Inc., Princeton, New Jersey, USA., Jan de Beur SM; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA., Marsteller D; Kyowa Kirin Inc., Princeton, New Jersey, USA.

Publikováno v: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Dec; Vol. 116 (6), pp. 1606-1614. Date of Electronic Publication: 2024 Oct 24.

Bronchial mucosal Interferon-α/β and pattern recognition receptor expression in experimental rhinovirus-induced asthma exacerbations

Autor: Zhu, J, Message, SD, Mallia, P, Kebadze, T, Contoli, M, Ward, CK, Barnathan, ES, Mascelli, MA, Kon, OM, Papi, A, Stanciu, LA, Edwards, MR, Jeffery, PK, Johnston, SL

Publikováno v: 125.e4

BACKGROUND: The innate immune system senses viral infection via pattern recognition receptors (PRRs) leading to type I interferon (IFN) production: their roles in rhinovirus (RV)-induced asthma exacerbations in vivo are uncertain. OBJECTIVES: To comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::535bfb70256c4c4dc2f2c3e34bfb58c0
http://hdl.handle.net/10044/1/58898

Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma

Autor: Zhu, J, Message, Sd, Qiu, Y, Mallia, P, Kebadze, T, Contoli, Marco, Ward, Ck, Barnathan, Es, Mascelli, Ma, Kon, Om, Papi, Alberto, Stanciu, La, Jeffery, Pk, Johnston, Sl

Publikováno v: CHEST Journal

Background The nature of bronchial mucosal inflammation and its physiologic and clinical significance in rhinovirus-induced asthma exacerbations is unclear. We investigated bronchial mucosal inflammatory response and its association with physiologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7bf6aa2446d03013b695b44cad3b2893

Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations.

Autor: Zhu J; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Message SD; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom., Mallia P; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom., Kebadze T; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Contoli M; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom; Research Centre on Asthma and COPD, University of Ferrara, Ferrara, Italy., Ward CK; Centocor, Malvern, Pa., Barnathan ES; Centocor, Malvern, Pa., Mascelli MA; Centocor, Malvern, Pa., Kon OM; Imperial College Healthcare NHS Trust, London, United Kingdom., Papi A; Research Centre on Asthma and COPD, University of Ferrara, Ferrara, Italy., Stanciu LA; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Edwards MR; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Jeffery PK; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Johnston SL; Airway Disease Infection, National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom. Electronic address: s.johnston@imperial.ac.uk.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2019 Jan; Vol. 143 (1), pp. 114-125.e4. Date of Electronic Publication: 2018 Apr 24.

Nasal nitric oxide: longitudinal reproducibility and the effects of a nasal allergen challenge in patients with allergic rhinitis

Autor: Boot, JD, de Kam, ML, Mascelli, MA, Miller, B, Gerth van Wijk, Roy, Groot, H, Cohen, AF, Diamant, Z

Publikováno v: Allergy, 62(4), 378-384. Wiley-Blackwell Publishing Ltd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::01fb04d2094dfafdfc1ce540f116998a
https://pure.eur.nl/en/publications/59056476-edb0-40bf-a05b-4c2b3e1d3211