Role of Hfe and hepcidin in the homeostasis of body iron levels

Autor: Mascarenhas, Monica Sousa Dias

Recent studies have suggested that hepatic iron stores and the response to anaemia and inflammation are dependent on the mouse strains used and their Hfe status. Hepcidin and iron transporters such as DMT1 and Iregl are regulator molecules important

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497921

Early warnings and repayment plans: novel trial management methods for monitoring and managing data return rates in a multi-centre phase III randomised controlled trial with paper Case Report Forms

Autor: Cragg, William J., Cafferty, Fay, Diaz-Montana, Carlos, James, Elizabeth C., Joffe, Johnathan, Mascarenhas, Monica, Yorke-Edwards, Victoria

Publikováno v: Trials, Vol 20, Iss 1, Pp 1-11 (2019)
Trials

Background Monitoring and managing data returns in multi-centre randomised controlled trials is an important aspect of trial management. Maintaining consistently high data return rates has various benefits for trials, including enhancing oversight, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a2af78d5f3060f0ec787b589c731b9
http://link.springer.com/article/10.1186/s13063-019-3343-2

18. The Needs of Low-Literate Migrants When Learning the English Language

Autor: Mascarenhas, Monica

Monica Mascarenhas considers language-teaching provision for migrants to Britain, its instrumentality, its universality and its oblivion to their backgrounds, concerns, losses, and aspirations. A former language lecturer, she collected the life stori

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=openedition_::f2489e1bca36bace75aa2bb0f0429e9a
http://books.openedition.org/obp/14117

Methods for delivering the UK's multi-centre prison-based naloxone-on-release pilot randomised trial (N-ALIVE):Europe's largest prison-based randomised controlled trial

Autor: Meade, Angela Mary, Bird, Sheila Macdonald, Strang, John, Pepple, Tracey, Nichols, Laura Lea, Mascarenhas, Monica, Choo, Louise, Parmar, Mahesh Kumar Bhikhubhai

Publikováno v: Meade, A M, Bird, S M, Strang, J, Pepple, T, Nichols, L L, Mascarenhas, M, Choo, L & Parmar, M K B 2017, ' Methods for delivering the UK's multi-centre prison-based naloxone-on-release pilot randomised trial (N-ALIVE) : Europe's largest prison-based randomised controlled trial ', Drug and Alcohol Review . https://doi.org/10.1111/dar.12592

INTRODUCTION AND AIMS: Naloxone is an opioid antagonist used for emergency resuscitation following opioid overdose. Prisoners with a history of heroin use by injection have a high risk of drug-related death in the first weeks after prison-release. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a8be1a7aa84f23beec11b56163c2c5a
https://kclpure.kcl.ac.uk/portal/en/publications/methods-for-delivering-the-uks-multicentre-prisonbased-naloxoneonrelease-pilot-randomised-trial-nalive(e1691218-ac2d-4dd7-9bb5-d12457bb3e1a).html

Liver Hepcidin mRNA Is down Regulated at High Liver Iron Burdens and up Regulated in HCV Infection in Thalassaemia

Autor: Mascarenhas Monica, Srai S. Kaila, Shah T. Farrukh, Porter B. John, Rafique Roozina

Publikováno v: Blood. 106:3592-3592

Rationale. Hepcidin is an important negative regulator of iron absorption from the gut and iron release from macrophages. Synthesis is increased by inflammation and decreased in iron deficiency. Iron overload conditions might be predicted to up-regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9909da9a3eb771d704f9d338de35962
https://doi.org/10.1182/blood.v106.11.3592.3592